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Son, Hyunsoo,Kim, Yoori,Park, Sangmin,Binns, Michael,Kim, Jin-Kuk Elsevier 2018 ENERGY Vol.157 No.-
<P><B>Abstract</B></P> <P>MEG (Monoethylene glycol) is a hydrate inhibitor used for the recovery of subsea oil and gas. For practical and economic reasons, it is necessary to extract and re-use the MEG through a regeneration unit which removes hydrocarbons, water and salts. The economic performance of regeneration process depends on MEG losses and the amount of heat and power required for the separation. Since recovering as pure MEG as possible without disturbances induced by salts is important to maintain process sustainability, this study focuses on the modeling and simulation of salt and water removal steps, including the prediction of hydrate inhibitors required for subsea condition. Also, design methods presented in this study systematically provide identification of appropriate configurations and operating conditions, with which the economic performance concerning MEG loss and energy consumption can be systematically evaluated. Models are developed in process simulators and validated with industrial data. Hydrate inhibitor recovery of 99.42% from the reclamation unit considered in this study is comparable to typical recoveries reported in commercial processes in the range of 99.4%–99.5%. It is also found that energy used for the separation of MEG from water in re-concentration unit accounts for at least 60% of total energy consumption.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Systematic operational analysis of MEG process for ensuring offshore flow assurance. </LI> <LI> Integrated process modeling for the design of MEG reclamation and re-concentration. </LI> <LI> Multi-period design framework for enhancing operability of MEG process. </LI> </UL> </P>
Neonatal Respiratory Morbidity in Twins according to Birth Order and Mode of Delivery
( Hyunsoo Kim ),( Jiyeon Kim ),( Sun Young Ko ),( Son Moon Shin ),( Yeon Kyung Lee ) 대한주산의학회 2018 Perinatology Vol.29 No.4
Objective: To compare neonatal respiratory morbidity of twins according to birth order related to gestational age and mode of delivery. Methods: We performed the retrospective research of the medical records of 3,224 neonates (1,612 twin pairs) born in a single center from January 2011 to December 2015. Subjects were classified into four gestational age groups: very (<32 weeks), moderate (32-33 weeks), late (34-36 weeks) preterm, and term (≥37 weeks) groups. We investigated clinical characteristics and respiratory morbidity according to birth order related to gestational age group and mode of delivery. Results: We found increased risk of respiratory morbidity in second-born twin than first-born twin (P=0.039). Second-born twin was associated with increased risk of respiratory distress syndrome (RDS) in late preterm group (odds ratio [OR] 2.8, 95% confidence interval [CI] 1.30-5.95), and transient tachypnea of newborn in term group (OR 1.4, 95% CI 1.03-1.81). In vaginal delivery mode, there was no difference of respiratory morbidity between first and second-born twin in each group, but in cases of Cesarean delivery, second-born twin was related with a greater risk of RDS in late preterm group (OR 2.3, 95% CI 1.07-5.09). Birth order and Cesarean section independently increased the risk of RDS (adjusted OR [aOR] 1.69, 95% CI 1.12-2.54; aOR 2.14, 95% CI 1.25-3.66, respectively). Conclusion: Second-born twin and Cesarean delivery are associated with increased risk of RDS, especially in late preterm twins.
Jun Son Young,Kim Young Ah,Lee Suk-Jun,Jung Woon-Won,Kim Hyun-Sook,Kim Sung-Soo,Kim Hyunsoo,Yong Dongeun,Lee Kyungwon 대한진단검사의학회 2023 Annals of Laboratory Medicine Vol.43 No.2
Background: Development of an accessible method to routinely evaluate the clonality of strains is needed in microbiology laboratories. We compared the discriminatory power of the Fourier-transform infrared (FTIR) spectroscopy–based IR Biotyper (Bruker Daltonics GmbH, Bremen, Germany) to matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS), using whole-genome sequencing (WGS) as the reference method. Methods: Eighty-three extended-spectrum β-lactamase–producing Escherichia coli isolates were tested using WGS, MALDI-TOF MS, and IR Biotyper. Simpson’s diversity index (SDI), a statistical analysis for testing the homogeneity of a dendrogram, and the adjusted Rand index (aRI) were used to compare the discriminatory ability between typing tests. Results: The SDI (95% confidence interval) was 0.969 (0.952–0.985) for WGS, 0.865 (0.807–0.924) for MALDI-TOF MS, and 0.974 (0.965–0.983) for IR Biotyper. Compared with WGS, IR Biotyper showed compatible diversity, whereas MALDI-TOF MS did not. The concordance and aRI improved from 66.3% to 84.3% and from 0.173 to 0.538, respectively, for IR Biotyper versus MALDI-TOF MS with WGS as the reference method. IR Biotyper showed substantially improved performance in strain typing compared with MALDI-TOF MS. Conclusions: IR Biotyper is useful for diversity analysis with improved discriminatory power over MALDI-TOF MS in comparison with WGS as a reference method. IR Biotyper is an accessible method to evaluate the clonality of strains and could be applied in epidemiological analysis during an outbreak of a health care facility, as well as for research on the transmission of resistant bacteria in community settings.
홰 종류 및 높이 설정에 따른 육계 생산성, 행동특성, 계육품질에 미치는 영향
김현수(Hyunsoo Kim),김희진(Hee-Jin Kim),전진주(Jin-Joo Jeon),손지선(Jiseon Son),유아선(Are-Sun You),강보석(Bo-Seok Kang),홍의철(Eui-Chul Hong),강환구(Hwan-Ku Kang) 한국가금학회 2021 韓國家禽學會誌 Vol.48 No.4
본 연구는 홰 종류 및 높이 설정에 따른 육계의 생산성, 혈액조성, 행동특성 및 계육품질에 미치는 영향에 대하여 조사하였다. 육계(Ross 308) 초생추(48.23±0.264 g) 수컷 912수를 공시하여 재질에 따른 홰 종류 3종(나무, 철제 및 플라스틱)과 높이 2수준(10→30 cm 변동, 10 cm 고정)의 3 × 2 요인으로 35일간 시험을 수행하였다. 체중 및 사료 섭취량은 개시일과 종료일에 측정하였다. 육계의 홰 이용도, 깔짚 품질, 발바닥피부염은 1, 3, 5주령에 측정하였으며, 혈청 생화학 조성 및 계육품질은 35일령에 분석하였다. 체중, 사료요구율, AST를 제외한 혈청 생화학 성분은 처리구간 유의적인 차이를 보이지 않았으며, 5주령의 발바닥피부염 발생 정도는 플라스틱(1.65) 처리구가 나무(1.25)와 철제(1.30)에 보다 유의적으로 증가 하였다(P<0.05). 홰 이용성을 분석한 결과, 모든 주령에서 점등 및 소등구간에는 나무, 철재, 플라스틱 처리구 순으로 유의적으로 이용 횟수가 높았으며(P<0.05), 3주령과 5주령에는 홰의 높이 고정 처리구가 변동 처리구보다 이용 횟수가 높았다(P<0.05). 가슴육 품질 분석결과, pH, 육색, 보수력은 홰 종류 및 높이 간 유의적인 차이를 나타내지 않았으나, 전단력은 나무, 철재, 플라스틱 순으로 유의적으로 높은 값을 나타내었다(P<0.05). 따라서 높이 설정에서는 10 cm 고정 처리구가 높은 이용도로 나타내었으며, 홰 재질은 다른 재질에 비해 나무 재질의 이용도가 높았고 AST 및 발바닥 피부염을 개선시키는 것으로 사료된다. This study investigates the effect of perch type and height on the growth performance, footpad dermatitis (FPD), blood parameters, behavioral characteristics, and meat quality of broilers. A total of 912 one-day-old male Ross 308 broilers (48.23± 0.264 g) were subjected to a three x two factorial design of three types of perch (wood, steel, plastic) and two levels of perch height (10→30 cm change, 10 cm fixed) over a five-week experiment. Growth performance, perch availability, litter quality, FPD incidence, serum biochemical parameters, and meat quality of the broilers were evaluated. There were no significant differences in the body weight, feed conversion ratio, and biochemical parameters (except for aspartate aminotransferase), pH, color, and water holding capacity. The incidence of FPD was significantly higher in the plastic perch group than in the wood and steel perch groups (P<0.05) at five weeks of age. Perch use was high in the order of wood, steel, and plastic groups in the daytime and nighttime at one, three, and five weeks of age (P<0.05). Perch use was higher in the 10 cm fixed group than the 10→30 cm group (P<0.05). The shear force of the breast significantly increased in the order of wood, steel, and plastic groups (P<0.05). In conclusion, the group with a fixed perch height of 10 cm had high perch usage. Additionally, the use of wooden perches was higher than that of other materials, and it lowered the incidence of FPD in broilers.
Lee, Hyunsoo,Son, Narae,Jeong, Hu Young,Kim, Tae Gun,Bang, Gyeong Sook,Kim, Jong Yun,Shim, Gi Woong,Goddeti, Kalyan C.,Kim, Jong Hun,Kim, Namdong,Shin, Hyun-Joon,Kim, Wondong,Kim, Sehun,Choi, Sung-Yoo The Royal Society of Chemistry 2016 Nanoscale Vol.8 No.7
<P>We investigated the subdomain structures of single-layer graphene oxide (GO) by characterizing local friction and conductance using conductive atomic force microscopy. Friction and conductance mapping showed that a single-layer GO flake has subdomains several tens to a few hundreds of nanometers in lateral size. The GO subdomains exhibited low friction (high conductance) in the sp(2)-rich phase and high friction (low conductance) in the sp(3)-rich phase. Current-voltage spectroscopy revealed that the local current flow in single-layer GO depends on the quantity of hydroxyl and carboxyl groups, and epoxy bridges within the 2-dimensional carbon layer. The presence of subdomains with different sp(2)/sp(3) carbon ratios on a GO flake was also confirmed by chemical mapping using scanning transmission X-ray microscopy. These results suggest that spatial mapping of the friction and conductance can be used to rapidly identify the composition of heterogeneous single-layer GO at nanometer scale, which is essential for understanding charge transport in nanoelectronic devices.</P>