근로자 건강증진전략을 위한 행동변화에 대한 요구도 평가

이강숙,임현우,구정완,홍현숙,이정민,이원철,박정일,맹광호,M, O'Donnel 大韓産業醫學會 1999 대한직업환경의학회지 Vol.11 No.4

Objectives : In order to evaluate the stage of behavior change for health promotion strategy in workplace Methods : Questionnaire survey was carried out for 309 workers who employed in H Electronics company in Kyong-in area from September to October 1998. Results : According to need assessment of four step such as precontemplation stage, contemplation stage, action stage, maintenance stage which were to change of behavior for health promotion, the percent for quitting smoking were observed 48.8%, 43.1%, 8.1%, 0%, and for the restriction of drinking were 29.8%, 10.6%, 9.3%, 5.3%; for fitness 11.1%, 31.0%, 37.3%, 20.6% in male 26.6%, 27.8%, 26.6%, 19.0% in female, for regular diet 26.1%, 19.8%, 38.7%, 15.3% in male, 27.8%, 22.2%, 40.0%, 10.0% in female and for stress management 5.8%, 10.6%, 8.7%, 75.0% in male, 13.6%, 22.7%, 19.7%, 44.0% in female. In heavy smoker(p=0.017) and heavy drinker,(p=0.021) the percent of precontemplation stage was significantly higher than in lower drinker and light smoker. Conclusions : This study suggested that company support for health promotion in workplace was and workers of high risk group for smoking and drinking were in precontemplation stage. So before conducting the health promotion program, health risk appraisal and need assessment for stage of behavior change should be taken for the efficient health promotion strategy.

모 컴퓨터 회사 근로자 건강증진 사업 전개를 위한 수요조사

임현우,안병용,최환석,박정일,김경수,이강숙,김정아,구정완 가톨릭대학산업의학쎈타 산업의학연구소 1997 韓國의 産業醫學 Vol.36 No.4

Before conducting the health promotion program, we surveyed the health risk appraisal(HRA) of 210 workers (186 men and 24 women) in a computer company, for the need assessment, selection of target population, priority setting, and as a standard for comparision after performing the program. The smokers were 115(88.6%), and drinkers (over 1 bottle of Soju per week) were 91(44.8%) in men. Entire women and 148(78.0%) men never or irregularly exercise. Type A personality were 73(39.2%) in men, 8(33.3%) in women, and 26(14.0%) of men and 6(25.0%) of women were high stress risk group. 53(25.2%) of men and 2(8.3%) of women were obese (BMI ≥25kg/m²), and workers who consumed exess of total calory compared with recommendation were 142(76.3%) in men and 18(75%) of women. By the health risk appraisal, it was suggested that smoking cessation program, drinking counselling, exercise prescription, stress management, and weight control program should be conducted effectively for the high risk group.

보건관리 대행사업장 근로자에서 건강증진에 대한 5년 사이의 지식, 태도 및 실천의 변화

임현우,김정아,안병용,박정일,구정완,이강숙 大韓産業醫學會 1998 대한직업환경의학회지 Vol.10 No.2

Before and after conducting the health promotion program by group occupational health service during 5 years, we surveyed knowledge, attitude and practice about general health (30 items) and occupational health(30 items) among 25 small and medium scale industry workers(before: 355 workers, after: 279 workers) for evaluation of effectiveness. The scores of knowledge for smoking, drinking, cholesterol, mental stress, management of hypertension, and risks in younger or women workers were significantly increased after conducting group occupational health service. The scores of attitude for controlling of fatty food consumption and cleaning workplace and bathing for health and that of practice for taking the periodic health examination and checking blood pressure were significantly increased but most of items in attitude and practice didn't be changed after services. According to sex, the scores of men were significantly increased in knowledge of general health, but there were not significant differences in age, job status and work duration group. In conclusion, through the group occupational health service during 5 years, only the scores of knowledge in general health were increased. It suggested that the effective program which can change workers' attitude and practice for health promotion, should be developed and conducted in small and medium scale industry workers.

The Transport Phenomena of a Series of Amides through the Copolymer Hydrogel Membranes

Koo, Hyeon-Sook,Jhon, Mu-Shik Korean Chemical Society 1980 Bulletin of the Korean Chemical Society Vol.1 No.4

Hydrogel membranes were prepared by copolymerizing 2-hydroxyethyl methacrylate (HEMA) and N-vinyl-2-pyrrolidone (VP) in the presence of the solvent and the crosslinker tetraethyleneglycol dimethacrylate (TEGDMA). By changing the monomer composition and the crosslinker content, different membranes were synthesized. Using these membranes, relative permeabilities and distribution coefficients for amides including urea were measured. The water contents in membrane were also measured. On the basis of solute-membrane matrix interaction, the results were interpreted.

Helical Periodicity of (dT)nㆍ(dA)nㆍ(dT)n Triple-Stranded DNA

Koo,Hyeon-Sook,Kim,Kihyun The Korea Science and Technology Center 1997 BMB Reports Vol.30 No.6

The helical periodicity of the triple-stranded (dT)n·(dA)n·(dT)n sequence was determined by measuring gel-mobilities of bent DNA fragments containing the sequence. In the bent DNA fragments, a GA22G·CT22C sequence was located between two bent DNA loci composed of six An·Tn repeats, and the DNA length between the bent DNA loci was varied by 1 base pair over a full helical turn. The gel mobility of each bent DNA fragment reflected the overall extent of DNA bending and varied with the DNA length between the two bent loci. Mobilities of the bent DNA fragments in 5% polyacrylamide gel were measured after preincubating the DNA fragments both in the presence and absence of CT22C oligonucleotide. By comparing the bent DNA fragments containing an intermolecular triplex structure with those of a genuine duplex structure in the gel mobilities, the helical periodicity of the Tn·An·Tn triplex DNA was determined to be 11.5 (±0.3) bp/turn.

DNA supercoiling by DNA helix - tracking proteins

Hyeon Sook Koo 생화학분자생물학회 1991 생화학분자생물학회 춘계학술발표논문집 Vol.- No.-

Dna2 Requirement for Normal Reproduction of Caenorhabditis elegans Is Temperature-dependent

Hyeon-Sook Koo,Kyoung-Hwa Lee,Myon Hee Lee,이태훈,Ji Won Han,Yong Jin Park,Joohong Ahnn,서연수 한국분자세포생물학회 2003 Molecules and cells Vol.15 No.1

Developmental Regulation of Caenorhabditis elegans DNA Topoisomerase I Expression

Koo, Hyeon-Sook,Jang, Yeon Joo,Park, HyungKi,Lee, JunHo The Korea Science and Technology Center 1998 BMB Reports Vol.31 No.3

The developmental regulation of Caenorhabditis elegans DNA topoisomerase I expression was examined using synchronized Caenorhabditis elegans cultures. Variations of te relative mRNA and protein levels of the enzyme during their development were measured by Northern and Western analyses, respectively. The mRNA level was the highest at the embryonic stage, decreasing rapidly to the one tenth level at the L1 state, and then increasing by a few fold at the L4 and young adult stages. The protein level was the highest at the L1 stage, with gradual decreasing at the following stages until it showed a slight increase at the young adult stage. Based on our results of the expressional regulation, the possible roles of DNA topoisomerase I in the development of C. elegans are discussed.

Deficiency of Bloom's Syndrome Protein Causes Hypersensitivity of C. elegans to Ionizing Radiation but Not to UV Radiation, and Induces p53-dependent Physiological Apoptosis

Hyeon-Sook Koo,Yun Mi Kim,Insil Yang,Jiyeung Lee 한국분자세포생물학회 2005 Molecules and cells Vol.20 No.2

Caenorhabditis elegans him-6 mutants, which show a high incidence of males and partial embryonic lethality, are defective in the orthologue of human Bloom’s syndrome protein (BLM). When strain him-6(e1104) containing a missense him-6 mutation was irradiated with γ-rays during germ cell development or embryogenesis, embryonic lethality was higher than in the wild type, suggesting a critical function of the wild type gene in mitotic and pachytene stage germ cells as well as in early embryos. Even in the absence of γ- irradiation, apoptosis was elevated in the germ cells of the him-6 strain and this increase was dependent on a functional p53 homologue (CEP-1), suggesting that spontaneous DNA damage accumulates due to him-6 deficiency. However, induction of germline apoptosis by ionizing radiation was not significantly affected by the deficiency, indicating that HIM-6 has no role in the induction of apoptosis by exogenous DNA damage. We conclude that the C. elegans BLM orthologue is involved in DNA repair in promeiotic cells undergoing homologous recombination, as well as in actively dividing germline and somatic cells.

중소규모 제조업체 근로자의 인구·사회학적 특성이 건강행동변화단계에 미치는 영향

구명회,임현우,박정일,이강숙,구정완 大韓産業醫學會 2002 대한직업환경의학회지 Vol.14 No.1

목 적 : 근로자 건강증진을 위한 사업장 건강증진 사업 프로그램 기획실에 건강 위험요인을 평가하고 근로자 특성에 4따른 행동변화단계를 조사하여 행동 변화단계에 따른 성공적인 근로자 건강증진전력을 위한 기초자료를 제공하고자 본 연구를 진행하였다. 방 법 : 경인지역이 중소 기업 제조업체 근로자 282명을 대상으로 설문조사를 수행하였으며, 일반적 특성에 대한 조사, 건강위험평가, 위험요인에 대한 행동변화단계를 조사하였다. 결 과 : 건강위험평가에서 흡연자는 남자 근로자에 서 65.7 %, 규칙적인 운동을 하지 않는 남자 근로자는 70.5 %, 여자 근로자는 86.1 %이었고 음주는 남자 근로자의 78.6 %, 여자 근로자인 50 %이었고 과음은 남자 근로자의 29.5 %, 여자 근로자의 11.1 %이었다. 건강한 생활습관으로의 행동변화단계로 계획전단계, 계획 단계, 실천단계, 유지단계 등 4개의 단계로 보면 근로자에서의 금연에 대하여 각각 40.5 %, 23.7 %, 12.1 % 및 23.7 %, 운동에 대하여는 18.4 %, 37.6 %, 17.7 % 및 26.3 %, 음주하였던 사람중 절주에 대하여는 20.9 %, 15.4 %, 10.0 % 및 53.7 %이었다. 흡연을 하는 보건관리자의 행동단계가 일반근로자 보다 유의하게 많았다. 운동에 대해서는 근로자중 50세 이상과 생산직 근로자에서 계획전단계가 다른 근로자보다 유의하게 많았다. 결 론 : 이상의 결과로 대부분의 근로자가 금연을 제외하고는 건강한 생활습관으로의 행동변화를 원하는 것을 알 수 있었으며 근로자의 특성에 따라 행동 변화단계가 다르므로 이를 고려한 다양한 건강증진 프로그램을 개발함으로써 참여율 및 성공율을 높일 수 있으리라 사료된다. Objectives : This research attempts to investigate the relationship between health risk factors and workers' behavioral changes based on individual worker's characteristics to allow the development of more effective health promotion programs in businesses places. Methods : A questionnaire survey was conducted with 282 workers employed in small to medium sized enterprises in the Kyong-in area of Korea. The questionnaire was composed of general characteristics, a health risk assessment and an evaluation of the stage of behavior change for health promotion strategy in the workplace. Results : The health risk assessment revealed that 65.7 % of male workers smoke, 70.5% of male workers do not exercise on a regular basis, 86.1 % of female workers do not exercise at all, and 78.6 % of male workers and 50 % of female workers drink alcohol. In addition, the survey identified that 29.5% of male workers are addicted to excessive drinking, as are 11.1% of female workers. Based on the four stages of behavioral changes that lead to health, the pre-contemplation stage, contemplation stage, action stage, and maintenance stage, 40.5 %, 23.7 %, 12.1 % and 23.7 % of workers are in these stages, respectively, with regards to quitting smoking. As for regular exercises, 18.4 %, 37.6 %, 17.7 %, and 26.3 % of workers belong to each stage, respectively. As for moderation in drinking, 20.9 %, 15.4 %, 10.0 %, and 53.7 % are in each stage, respectively. The rate of health managers in the active stage of quitting smoking is significantly higher than that of general workers. Among the workers who do not exercise on a regular basis, workers over 50 years-old and blue color workers are more common in the precontemplation stage than any other worker groups. Conclusions : The results of this study suggest that the stages of behavioral change vary with worker characteristics. An awareness of the effects of the high risk factors is essectial for promoting workers' attendance in health promotion programs.