A Study on Small Business Development and Support Policies

Yun,Jeong-keun,Jeong,Eun-hye 한국유통과학회 2011 한국유통과학회 학술대회 논문집 Vol.2011 No.-

The number of small businesses being founded in the nation is constantly increasing and various kinds of aggressive efforts are being made to have competitiveness. As such, political support by the government with regards to small businesses that has productivity and competitiveness needs to increase. Foundation of small businesses is being promoted by the Government to boost the economy, and interest in foundation of the business is high amongst not only college students but even general workers. Thus, the purpose of this study is to examine problems regarding foundation of small businesses and to give new businesses competitive edge by presenting political answers to these problems. After analysing status and current issues of foundation of small business, the paper suggested positive policy alternatives. Existing studies on small businesses were focused on promotion of small and medium distributors, and studies on policy alternatives aimed directly at promoting the businesses are insufficient. Further studies are needed to examine political alternatives from point of view of roles and support of non-profit organizations that the Government is responsible for support of small business.

전문비서직에 대한 이대 비서학과 학부학생들의 의식구

구효선,김경화,윤혜정,이지연,정은희,강은정,김윤희,신해정 이화여자대학교 법정대학 비서학과 1997 비서학연구 Vol.- No.17

치매환자 조호자를 위한 교육지지프로그램의 효과성에 관한 비교연구

송 흡(Heup Song),강재명(Jae Myeong Kang),김병규(Steven B. Kim),조성진(Seong Jin Cho),윤선경(Seon kyung Yun),윤혜진(Hye jin Yoon),연병길(Byeong Kil Yeon) 대한노인정신의학회 2017 노인정신의학 Vol.21 No.1

Objective:We studied the effect of Hyu-Sig-Gong-Gan and Hye-Ah-Rim on several evaluations and compared the two programs. We then investigated factors associated with the difference between pre- and post-ratings. Methods:Thirty-six patients were randomized to Hyu-Sig-Gong-Gan (n=23) or Hye-Ah-Rim (n=13). We tested for the effect of each program on several evaluations and compared the two programs through Zarit Burden Interview (ZBI), Center for Epidemiologic Studies-Depression Scale, Dementia Attitude Scale (DAS)-intelligence, DAS-comfort and DAS-total. We then investigated whether the difference between pre- and post-rating depends on other factors. Results:We observed significant positive effect of Hyu-Sig-Gong-Gan on DAS-comfort (t=1.843, p=0.039) and significant positive effect of Hye-Ah-Rim on ZBI (t=-2.327, p=0.019), DAS-comfort (t=2.241, p=0.022), and EuroQol-5 Dimensions-Visual Analogue Scale (t=2.537, p=0.013). For comparing the two programs, we found a lack of evidence for the difference in any of the five commonly observed evaluations. In the secondary analysis, we observed a strong trend that the two programs were particularly effective for caregivers with negative pre-ratings. Conclusion:The two programs showed positive effects on the various evaluations, but some evaluations could not reach statistical significance. The programs appear to be particularly helpful for those who are in need before the program participation.

수박 덩굴마름병 저항성 판별을 위한 SNP 표지인자 탐색

이혜은,홍종필,서혜영,허윤찬,안율균,김진희,김도선 忠北大學校 農業科學硏究所 2015 農業科學硏究 Vol.31 No.2

:Watermelon (Citrullus lanatus) is an important vegetable crop in the world and contains various health promoting compounds including many antioxidants such as lycopene and beta-carotene. Genetic diversity of cultivated watermelon is very narrow, which is one of major factors limiting the improvement of watermelon breeding program. Gummy stem blight (Didymella bryoniae (Auersw.)) is one of the most destructive diseases and causes crown blight, defoliation and fruit rot, resulting in severe production loss in watermelon. Single nucleotide polymorphisms (SNPs), important molecular markers for genetic studies are frequent sequence variation in the plant genome. This study was performed to develop SNP markers related to gummy stem blight resistance from three watermelon lines, one susceptible and two resistant to gummy stem blight. Of them, 22 SNP primers which were sequence information on SNPs derived from comparing a resistant and susceptible line was used for high resolution melt analysis. A total of 14 candidate SNP primers were detected melt temperature difference. These SNP primers can be useful for developing disease resistance-related markers and, therefore, beneficial to watermelon breeding program.

6-(3,4-디클로로페닐)아미노-7-클로로-5,8-퀴놀린디온의 항진균작용 및 안전성 평가

윤여표,김동현,이병무,허문영,정해문,강혜영,최정아,김도희,유충규 성균관대학교 약학연구소 1998 成均藥硏論文集 Vol.10 No.1

6-(3.4-Dichlorophenyl)amino-7-chloro-5.8-quinolinedione (RCK50) was tested for antifungal activities in mice systemically infected with Candida albicans. The therapeutic potential of RCK50 was also assessed in comparison with ketoconazole. RCK50 had ED_50 0.22±0.01 ㎎/㎏. Ketoconazole as a positive control had ED_50 6.00±1.70 ㎎/㎏. Intraperitoneally administered RCK50 at the ED_50 for 7 days and 14 days reduced Candida albicans colony count in the kidneys and liver. And administered RCK50 at the ED_50 for 14 days improved survival rates. The genotoxicities of RCK50 had been evaluated. RCK50 was negative in Ames test with Salmonella typhimurium and chromosomal aberration test in CHL cells. RCK50 did not show any clastogenic effect in mouse peripheral blood and was negative in mouse micronucleus assay. These results indicate that RCK50 has no genotoxic potential under these experimental conditions. Acute oral toxicity studies of RCK50 were carried out in ICR mice of both sexes. RCK50 did not show acute oral toxicities and LD_50 values were over 2.850 ㎎/㎏ in ICR mice.

의료시장개방에 따른 병원마케팅 전략에 관한 연구

문혜옥,최윤홍 호남대학교 대학원 2010 호남대학교 대학원 논문집 Vol.7 No.-

As is investigated above, hospitals in Korea have entered into an extreme struggle for survival. Since the circumstances surrounding hospitals in this endless competition age are progressing at a fast pace, they are doing their best in order to survive but they can not be sure of a promising future unless they do not bring about changes in management and great innovations. In addition, they are faced with a market opening in medical care. In order that they may be able to efficiently meet these changes, it is imperative that they should be armed with patient-oriented marketing and that they should come up with a strategy that would enable them to carry out a managerial rationalization and innovative changes. Namely, in order to meet patients' needs, they need to have a patient-oriented and community-oriented management instead of a hospital-oriented management, making great efforts to offer better services. Conclusively speaking, the degree of patient satisfaction with hospital services will play a pivotal role in determining hospital profitability. If a hospital offers satisfaction to clients, it will continue to have clients and secure a good reputation, thereby further bringing in more satisfaction, more patients and more profits. But if patients are satisfied, the number of patients will decrease resulting in less profits. So, it is very important hospitals conduct a survey to find out why patients are not satisfied and to accommodate any complaints into their managerial decisions. Based on these factors, hospitals should develop their own core capabilities that others can not emulate easily so that they may be competitive in the medical market. Additionally, there are hosts of data that show that hospitals satisfying both patient satisfaction and clinical results succeed in their management. This study aims to show that hospitals need to have hospital-marketing strategies that offer differentiated services in their attempt to provide patient-oriented integrative services along with managerial changes in the information age. First, in terms of service strategies they should offer specialized medical care and recruit top-class medical professionals, be equipped with ultra-modern medical equipment and facilities, increase the professionalism and kindness of medical personnel, and build up mutual trust between medical personnel and patients. Second, in terms of price strategies medical fees, medical cost reduction, credit card use, fee payment requirements, etc. do not play an important role as a universal medical insurance system is in place. Third, in terms of distribution channel strategies it would expedite patient approach and communication if hospitals do their business in a fast and convenient manner when they provide patients with swift and exact test results. Fourth, in terms of promotion strategies hospitals need to activate promotion and put into place a medical information system. As investigated above, applying marketing strategies to hospital management would be of great help in solving difficult issues facing hospitals now. As far as hospital services are concerned in the efforts to efficiently run hospitals, hospitals are urged to consider the following improvement ideas: expansion of service areas for local residents, simplification of patient registration for medical care, shortening the waiting time, better explanation on the part of medical personnel, improving hospital cleanliness and atmosphere, running wards without visitors from patient families, meal system which patients can choose, medication delivery system, differentiated comprehensive health checkup services, etc. Hospitals in Korea are being run not by expert mangers but by doctors who are well-educated in their management, so they need to learn professional management skills in order that they may run their hospitals in a rational and organized manner. In order to achieve hospitals' goals and objectives in a successful manner, the whole hospital organization should make every effort. Now, marketing for hospital should not approached in a near-sighted manner. They had better recruit marketing specialists for active marketing activities. In addition, the swift development and application of new services are required for providing medical services in an efficient manner. These marketing activities are playing an important role in the survival of hospitals.

일부 운수사업장 근로자의 건강진단 유소견자의 사후관리 실행과 관련요인

윤혜은,박종,이영선,강성득,김철호 조선대학교 2003 The Medical Journal of Chosun University Vol.28 No.1

Objective : The purpose of this study was to find the relationship between the follow-up management status for medical problem to be treated and various characteristics of some workers at transportation business. Methods : A questionnaire survey was made toward 183 workers with medical problem(C and D2) among 945 examine in 1997. Results: Sixty four point five percent of surveyee received the examination result report and 40.5% were explained about the result 80.3% of surveyee answered that they knew the result of health examination. Most workers felt the necessity of the health examination, but 54.1% were dissatisfied with present health examination system and 66.7% pointed it out as nominal The rate of follow-up management for the medical problem was 62.8% By the multiple logistic regression the follow-up management rate for those who knew the health examination result were 2.98 times higher than those who didn't know the result (OR=2.98, 95% CI 1.41~6.29) The rate for those who perceived the medical problem already were 2.64 times higher than those who perceived the problem for the first time (OR=2.64, 95% CI 1.13~6.15). The rate for those who had subjective symptoms were 2.83 times higher than those who didn't have subjective symptoms. Conclusion : sixty two point eight percent of workers with medical problem performed the follow-up management and perception of health examination result, perception of the problem in the past and experience of subjective symptoms were related with the follow-up management.

土壤中에 있는 phenol分解細菌의 分離·同定 및 phenol分解能에 關한 考察

尹惠禎,金惠泳 梨花女子大學校 韓國生活科學硏究院 1986 韓國生活科學硏究院 論叢 Vol.38 No.-

Phenol은 有毒性이고 分解되기 어려운 環境汚染物質이며 大部分 芳香族化合物의 中間代謝産物이다. 또한 各種 産業工程에서 高濃度로 排出되기 때문에 그 毒性으로 인해 處理時 問題를 일으키므로, phenol 廢水處理를 위하여, phenol을 sole carbon source로 利用하는 菌株를 土壤으로부터 分離하여, 그 形態學的·生化學的 特性에 의해 同定하였으며, 各 分離菌株의 溫度別 phenol分解能을 比較하여, 優秀菌株에 대하여 phenol濃度別 分解試驗을 實施하였고, 活性汚泥法으로 phenol廢水를 處理하여 다음과 같은 結果를 얻었다. 1. 18個 地域의 土壤試料中 4個 地域의 土壤으로부터 6株의 phenol分解細菌이 分離되었으며 모두 Pseudomonas屬이었다. 2. 初期 phenol濃度를 500mg/ℓ로 하여 溫度別 分解試驗을 한 結果, Strain Ⅰ,Ⅱ,Ⅲ는 30˚C에서 Strain Ⅳ, Ⅵ는 25˚C에서, Strain Ⅴ는 37˚C에서 各各 最高分解率을 나타내었다. 그 中 分解能이 가장 秀麗한 菌株는 Strain Ⅲ로, 20∼37˚C에서 높은 分解率을 나타내었으며, 특히 30˚C에서는 36時間後 99%가 分解되었다. 3. Strain Ⅲ에 의한 phenol濃度別 分解試驗結果, 10,50,100,200,500mg/ℓ의 境遇는 各各 3,6,12,24,36時間에 99%가 分解되었다. 1,000mg/ℓ以上에서는 顯著한 lag phase가 있었으나, 1,000mg/ℓ의 境遇 66時間後 99%가, 2,000mg/ℓ의 境遇 108時間後 98%가 分解되었다. 그러므로, Strain Ⅲ는 비록 分解에 長時間을 要하나 2,000mg/ℓ의phenol도 sole carbon source로 分解可能한 高活性菌株였다. 4. 順應活性汚泥를 利用하여, 100~800mg/ℓ의 phenol廢水를 處理한 結果, 滯留時間을 平均 28時間으로 하여 好條件에서 平均 99.9% 處理되었다. Bacteria that can degrade the toxic and persistent pollutant, phenol, were isolated from soil and identified. Their phenol-degradabilities at various temperatures were compared, superior strain was selected and its phenol-degrading activity was tested at various concentrations of phenol. Phenol-wastewater was treated with acclimated and activated sludge. The results are as follows: 1. Six phenol-degrading bacteria were isolated from four of eighteen soil samples and all of them were identified as genus Pseudomonas by morpho-logical and biochemical characteristics. 2. Optimum temperature of Strain Ⅰ, Strain Ⅱ, and Strain Ⅲ was 30˚C, Strain Ⅳ and Strain Ⅵ was 25˚C and Strain Ⅴ was 37˚C. Of them, Strain Ⅲ had superior degradability at wide temperature range, 20~37˚C, especially, at 30˚C, Strain Ⅲ could degrade 99% of initial phenol 500mg/ℓ after 36 hours. 3. From the test of phenol-degrading activity of Strain Ⅲ at various concentrations of phenol, Strain Ⅲ was highly active strain capable of degrading phenol 2,000mg/ℓ as a sole carbon source, although it took a long time to do. 4. Phenol removal rate in the acclimated and activated sludge reactor fed phenol at 100~800mg/ℓ and operated with retention time of 28 hours in the optimum conditions was 99.9%.

Aloe vera가 Alloxan 糖尿흰쥐의 血糖量 및 Insulin量에 미치는 영향에 관한 硏究

尹再順,金惠善 梨花女子大學校 韓國生活科學硏究院 1983 韓國生活科學硏究院 論叢 Vol.31 No.-

Aloe vera Linne가 組織再生作用과 細胞復活作用이 있으며 췌장 β-cell의 insulin分泌上皮細胞의 增植過程을 촉진한다는 報告가 있어 A. vera의 糖尿病에 對한 效果와 그 作用機轉을 규명하고 저 alloxan 糖尿흰쥐와 epinephrine에 의한 一時的 過血糖흰쥐에게 A. vera, chloropropamide 또 두 藥物을 倂用投與하여 血糖量과 glycogen量 및 血中 insulin量의 變化를 Somogyi-Nelson法과 Radioimmunoassay法으로 各各 測定하였다. A. vera는 alloxan糖尿흰쥐에 있어서 血糖量降下作用과 肝藏中 glycogen含量增加作用이 있었으며 epinephrine投與에 의한 一時的過血糖흰쥐에 對해서 A. vera前處置로 血糖量上昇作用이 抑制되었다. 또한 alloxan 糖尿흰쥐에 對해서 A. vera는 insulin分泌促進作用으로 血中 insulin量이 增加되었다. They reported that Aloe vera was effective in regeneration of wound tissues and cells, and that Aloe vera stimulated the proliferative process in regeneration of insular epithelium of the pancreas. This experiment was carried out to investigate the effect of Aole vera on Diabetes mellitus. Crud powder of Aloe vera and chloropropamide were given orally to alloxan diabetic rats either alone or in combination. Level of blood glucose and serum insulin in alloxan diabeic rats were measured by Somogyi-Nelson method and radioimmunoassay method respectively. We also investigated that effect of Aloe vera on blood glucose level in transient hyperglycemic rats by epinephrine. Thus, it is possible to conclude that Aloe vera had lowering effect on blood glucose level and increasing effect on glycogen content in alloxan diabetic rats, inhibiting effect on induction of transient hyperglycemia by epinephrine, and stimulaing effect on the recretion of insulin in alloxan diabetic rats.

체질량지수와 간기능 이상과의 관련성

윤혜은,류소연,강명근,박종,김기순 朝鮮大學校 附設 醫學硏究所 2005 The Medical Journal of Chosun University Vol.30 No.1

Objective: To investigate the relationship between body mass index (BMI) and liver function abnormalities in the general population in Korea. Methods: The study subjects were 5765 persons who were received questionnaire survey and health examination of national health and nutrition survey in 1998, 20-59 years in age and had no history of viral hepatitis. BMI was categorized by quartile and abnormal liver functions were defined aspartate aminotransferase (AST) >30 U/L or alanine aminotransferase (ALT) >35 U/L in serum level. In order to identify the association of BMI and abnormal liver function, chi-square test and multivariate logistic regression analysis were used. Results: The abnormality rates of AST were 35.0% in male and 13.4% in female. The abnormality rates of ALT were 35.8% in male and 11.1% in female. After controlling for the other covariates, the multivairate logistic regression analysis showed that BMI was the significant related factor of abnormal AST (male; odds ratio=1.25; 95% confidence interval=1.15-1.36, female; odds ratio=1.14; 95% confidence interval=1.02-1.26) and abnormal ALT (male; odds ratio=1.87; 95% confidence interval=1.71-2.04, female; odds ratio=1.56; 95% confidence interval=1.38-175). Conclusions: We identify that BMI was the significant risk factor of non-viral liver disease with abnormal liver functions. A large-scale investigation will be suggested in the future to demonstrate the causal-effect issue between abnormal liver function and obesity.