목재가 선적된 선창에서 발생한 산소결핍에 의한 질식사

김동훈,김기권,장태정,김정란,이구,김수근,임현술 大韓法醫學會 2001 대한법의학회지 Vol.25 No.1

Oxygen deficiency has been frequent in a clouted space. Wood consumes oxygen and discharges carbon dioxide Instead of photosynthesis in closed space without light, so do some microorganisms on the surface. We experienced a case that a healthy Insect-proofer fell down and died of asphyxia on stair-board at 7 m below the hatch of the cargo-hold shipping wood Analysis of gases in cargo-hold revealed O2; 12.3%, CO; 105 ppm, CH4; 2.7%, and H2S; 1.9% at 1 m below the hatch, and then O2; 6.1%, CO; 220 ppm, CH4; 2.9%, and H2S, 2.3 ppm at 2.5 m below the hatch. Autopsy findings were unremarkable. We justiced the cause of death asphyxia due to oxygen deficiency. As seen in this case, the serious oxygen deficiency was accounted for oxygen consumption by wood and microorganisms.

여성노인의 저항운동 시 세트구성 방법의 차이가 Myokine에 미치는 영향

김명수 ( Kim¸ Myung-soo ),이승환 ( Lee¸ Sung-hwan ),민병남 ( Min¸ Byung-nam ),김재훈 ( Kim¸ Jae-hoon1 ),방현석 ( Bang¸ Hyun-seok ),김성희 ( Kim¸ Sung-hee ) 한국융합과학회(구 한국시큐리티융합경영학회) 2020 한국융합과학회지 Vol.9 No.4

연구목적: 본 연구는 여성노인을 대상으로 저항운동 시 사용되는 set구성 방법에 중 ascending set, descending set, drop set를 각각 적용시켜 Myokine의 변화를 알아보고자 하였다. 연구방법: 연구대상은 노인복지시설을 이용하고 있는 만 65-72세 사이의 여성노인 32명을 대상으로 ascending set, 8명, descending set 8명, drop set 8명, control group 8명으로 구분하였다. 자료처리는 반복측정에 의한 이원변량분석(two-way ANOVA with repeated measure)을 사용하였으며, 유의도는 .05로 하였다. 결론: 운동프로그램은 12주간 주 3회 실시하였으며, 신체구성과 IL-15, BDNF, VEGF, Irisin의 변화를 관찰하였다. 연구결과 신체구성의 체중, 체지방률, 제지방량 모두 유의한 차이가 없었다. IL-15와 BDNF는 운동 전·후의 비교결과 Descending set와 Drop set에서 운동 후 유의하게 증가하였고, 집단 간의 차이에서 Descending set와 Drop set 집단이 대조집단에 비하여 높게 나타났다. VEGF는 운동 전·후의 비교결과 Descending set와 Drop set 집단이 유의하게 증가하였으며, 집단 간의 차이에서 Descending set와 Drop set가 Ascending set와 control group 보다 높게 나타났다. Irisin은 집단 간 차이는 없었지만 Ascending, Descending, Drop set집단에서 운동 전에 비하여 운동 후 유의한 차이로 증가하였다.. Purpose: The purpose of this study is to identify the change of Myokine by applying ascending set, descending set, and drop set which are set composition used during elderly women’s resistance training. Method: 32 participants aged 65 to 72 who were users of welfare facilities for the aged were divided into 4 groups. They were ascending set group of 8, descending set group of 8, drop set group of 8, and control group of 8. The training program was conducted 3 times a week for 12 weeks and the change of body composition, IL-15(interleukin-15), BDNF(brain derived neurotrophic factor), VEGF(Vascular endothelial growth factor) and Irisin was observed. Two-way ANOVA with repeated measure was used for data processing. Result: The result of this study is as follows. Weight, %fat, and LBM(lean body mass) without fat showed no significant change. IL-15 and BDNF increased significantly after training in Descending set group(p<.05; p<.01)and Drop set group(p<.01; p<.05). VEGF significantly increased in descending set group(p<.01) and drop set group(p<.05). Among groups, VEGF was higher in descending set and drop set groups than ascending set and control groups. Irisin showed no difference between groups, but it showed significant increase after training in ascending(p<.05), descending(p<.05), and drop set groups(p<.05).

捻轉法이 竝行된 鍼刺戟 및 電鍼刺戟이 鎭痛效果에 미치는 影響

Park, Dong-Seok,Kim, Ji-Hoon,Min, Byung-Il,Oh, Soo-Myung 경희대학교 동서의학연구소 1999 INTERNATIONAL SYMPOSIUM ON EAST-WEST MEDICINE Vol.1999 No.1

Dong-Seok Park¹, Ji-Hoon Kim¹ and Byung-Il Min, Soo-Myung Oh,³¹Department of Acupuncture and Moxibustion, College of Medicine, ²Department of Physiology, College of Medicine, And ³East-West Medical Research Institute, Kyung Hee University,Seoul, Korea. Analgesic Effect of Manual Acupuncture and Electroacupuncture combined with Twirling Method. Proceeding of International Symposium on East-West Medicine Seoul. 187-200, 1999.-Twirling the needle (TN) is one of several needing methods frequently used for acupuncture in the oriental medicine. The present study was conducted to see if TN enhanced the antinociceptive effect produced by plain-or electroacupuncture in the rat tail flick test. Rats (Sprague-Dawley, 200-300g)lightly anesthetized with thiopental sodium(40mg/kg, i.p.) were used in the tail-flick test. The basal reaction time for tail-flick was 2 sec. For "plain" acupuncture(PA), a needle was inserted for 20 min into a Chock-samni (ST36) acupuncture point which (is located at the anterior tibial muscle and about 10mm below the knee joint). For electroacupuncture(EA), train-pulses(3 Hz,0.3-ms pulse width, 0.2-0.3mA) were applied to the inserted needle for the period of insertion. For combining TN with either PA or EA, TN was performed during the each acupuncture period. Two methods for TN were used; twirling 3 times for 1 second persisted for 1 min in every 5 mins(long-duration and long-interval;LDLI) and twirling 3 times for 1 second persisted for 10 sec in every 1 min(short-duration and short-interval;SDSI). PA and EA produced an increase in tail flick latency (TFL); peak increases were 21.3±5.1% and 42.1±17.3% of the pre-acupunture control, respectively, and occurred immediately after cessation of 20min-acupuncture. Performing TN combined with PA increased TFL more than PA itself by showing a greater peak increase in TFL when performed with a SDSI-TN than with a LDLI-TN(60.6±12.5% and 42.7±22.7% of the pre-acupuncture control, respectively). Performing TN combined with EA also increased TFL more than EA itself and a greater peak increase in TFL was observed with a SDSI-TN as compared to a LDLI-TN(77.5±13.8% and 67.3±14.0% of the pre-acupuncture control, respectively). These results indicate that TN enhances both PA-and EA-produced antinociception where an greater enhanced antinociception than a LDLI-TN. It is suggested that performing a SDSI-TN combined with EA seems to be one of the most effective ways to produce analgesia.

Apoptotic Effect of Co-treatment with Chios Gum Mastic and HS-1200 on G361 Human Melanoma Cell Line

Young-Joo Hur,Young-Ki Kim,Hyun-Ho Kwak,Gyoo-Cheon Kim,Seung-Eun Lee,In-Ryoung Kim,Chul-Hoon Kim1,Bong-Soo Park 대한해부학회 2009 Anatomy & Cell Biology Vol.42 No.2

Chios gum mastic (CGM) is a resinous exudate obtained from the stem and the main leaves of Pistacia lenticulus tree native to Mediterranean areas. Recently it reported that CGM induce apoptosis in a few cancer cells in vitro. Bile acids and their synthetic derivatives induced apoptosis in various kinds of cancer cells and anticancer effects. It has been reported that the synthetic chenodeoxycholic acid (CDCA) derivatives showed apoptosis-inducing activity on various cancer cells in vitro. This study was undertaken to investigate the synergistic apoptotic effect of cotreatment with a natural product, CGM and a CDCA derivative, HS-1200 on G361 human melanoma cells. To investigate whether the co-treatment of CGM and HS-1200 compared with each single treatment efficiently reduced the viability of G361 cells, MTT assay was conducted. To investigate augmentation of apoptosis in G631 cells co-treated with CGM and HS-1200, DNA electrophoresis, Hoechst staining, proteasome activity assay, flow cytometry, Westen blot analyses, immunofluorescent staining and confocal microscopy were performed. In this study, G361 cells co-treated with CGM and HS-1200 showed several lines of apoptotic manifestation such as nuclear condensations, DNA fragmentation, the reduction of MMP and proteasome activity, the decrease of DNA content, the release of cytochrome c into cytosol, the translocation of AIF and DFF40 (CAD) onto nuclei, activation of caspase-9, caspase-3, PARP and DFF45 (ICAD), and up-regulation of Bax whereas each single treated G361 cells did not. Although the single treatment of 40 μg/mL CGM or 25 μM HS-1200 for 24 hrs did not induce apoptosis, the co-treatment of them induced prominently apoptosis. Therefore, combination therapy of CGM and HS-1200 could be considered, in the future, as an alternative therapeutic strategy for human melanoma.

TQM과 6시그마 경영에 관한 고찰 : 서비스산업을 중심으로 Primarily on service industry

김동훈,고수복,장영준 한국품질경영학회 2002 품질경영학회지 Vol.30 No.3

In order to carry out TQM and 6 Sigma management, it is the key elements to make clear a goal and a mission. Above all, we can succeed in achieving a dramatic change and a great outcome only when we make clear the method, incentives, organization and plans under the clear objective. In order to secure the competitiveness against the external challenge, it is essential to keep the several crucial factors such as CEO's will, the systematic process to measure and manage, monitoring to satisfy customer's needs and an aggressive development of TQM activity to encourage the endeavour of the relentless enhancement, and also a positive effort is to be made for evaluating all quality culture like training experts internally by an outstanding training program under CEO's firm leadership. This study is carried out to understand that which features and factors of success can exist in a company culture if a company accepts a theoretical basis and concept, the general of TQM and 6 Sigma which are one of a management strategy, and carries out TQM and 6 Sigma for achieving improvement of quality and customer's satisfaction.

신경망 예측 HMM을 이용한 음절인식

김수훈,김상범,김주성,허강인 東亞大學校 附設 情報通信硏究所 1996 情報通信硏究所論文誌 Vol.4 No.1

The exsiting CHMM is hard to express time-transient-variation. To solve such problem, we proposed a new method that is the hybrid network of the feed-forward networks and the HMM. The network is trained to predict the feature vector, varies in each time, is used instead of the mean vector in the HMM, Hence the dynamic feature of speech pattern is provided for the HMM. At the experiment, we compared the result of CHMM+MCEP, CHMM+MIX with NNPHMM. At the result, we got the recognition rates of 73.8% for NNPHMM.

補中益氣湯 및 少陰人 補中益氣湯이 S-180에 對한 抗腫瘍效果와 Cyclophosphamide에 依한 副作用에 미치는 影響

金秀鎭,金聖勳,林樂哲 대한동의병리학회 1993 동의생리병리학회지 Vol.8 No.-

연구배경 : 암은 사망률 1위를 차지하고 있는 질환으로서, 치료는 수술요법, 방사선요법, 화학요법 및 면역요법 등을 주로 활용하고 있는데, 그 중에서도 활용도가 높은 항암제에 의한 화학요법은 암종에 대한 감수성 차이, 치료후의 부작용, 재발 및 합병증 등의 문제점으로 부작용을 감소시키면서 항암효과를 높이는 치료법이 요구되고 있다. 이에 암에 응용될 수 있는 한방제재를 개발하고 있는 암의 치료에 기여하고자 한다. 방법 : Sarcoma 180을 이식하여 생쥐의 생명연장율과 cytophosphamide를 다량 투여하여 부작용을 유발시킨 백서의 GOT, GPT활성도, BUN 및 creatinine 함량을 측정하였다. 결과 : 실험군에서 공히 생명연장 효과가 인정되었고, GOT, GPT활성도도 유의성이 인정되었다. 혈청중 BUN 및 creatinine 함량은 소음인보중익기탕군에서 유의성이 인정되었고, 보중익기탕군에서는 유의성은 없었으나 감소하는 경향이 있었다. 결론 : 보중익기탕 및 소음인보중익기탕은 정기를 보익하고 면역기능을 촉진시켜 암종을 억제하는 효과가 있어, 암의 한방치료 및 예방에 응용할 수 있을 것으로 사료된다. Experiment was done to study the effects of liquid extract of Bojungikgitang(BIT) & Soeuminbojungikgitang(SBT) on the antitumor activity against S-180 and the reduction of side effects induced by cyclophosphamide. The results were obtained as follows : 1. The survival rate against S180 was increased in both BIT-treated group and SBT-treated group. 2. GOT was significantly decreased in both BIT-treated group and SBT-treated group as compared with the control group. 3. GPT was significantly decreased in both BIT-treated group and SBT-treated group as compared with the control group. 4. The amount of serum BUN was significantly decreased only in SBT-treated group. 5. The amount of serum creatinine was significantly decreased only in SBT-treated group. From above results, it was thought that Bojungikgitang & Soeuminbojungikgitang had antitumor activity against s-180 and the reduction of side effects induced by cyclophosphamide.

甲殼類의 分類學

金熏洙 全北大學校 生物學硏究所 1981 生物學硏究年報 Vol.2 No.-

甲殼類(Crustacea)는 절지동물의 한 綱 또는 上綱인데, 이것은 무척추동물 중에서 가장 크고 또, 가장 다양한 무리들 중의 하나이다. 많은 종류의 새우류ㆍ게류가 경제적으로 중요하다는 것이 옛날부터 인식되어 왔고, 육수학자들은 작은 갑각류의 무리들이 호수나 계류의 생태계에 공헌하는 바가 크다는 것을 인색해 왔으며, 어업 생물학자들은 많은 종류의 부유성 갑각류가 어류의 먹이사슬에 중요한 구실을 한다는 것을 알게 되었다. 최근에는 저서생물 생물학자들과 생태학자들은 광범위한 저서성 갑각류가 군집 내부의 영양 단계와 에너지 순환에 절대 필요한 구실을 다하고 있다는 것을 발견해 왔다. 이렇게 갑각류는 매우 중요한 분류군이라고 할 수 있다.

Distraction divice를 이용한 수지연장술 치험례

김수신,주훈성,김우경,정전은 大韓成形外科學會 1991 Archives of Plastic Surgery Vol.18 No.2

The goal of reconstructive hand surgery is to maintain the normal mobile and sensory function of the hand while aesthetically be acceptable. In cases of congenital or post-traumatic shortening and loss of the digit, it is very important to achieve sufficient length of the digit with regard to functional and aesthetic aspect. The initial application of the distaction bone lengthening technique to the upper extremity reconstruction was performed by Matev(1967) for the correction of post-traumatic thumb deformities with first metacarpal lengthening. Matev and others have subsequently applied this method to congenital hand malformations and dislocations. The advantages of this method are; first, there is minimal bone resorption to the interpositional bone graft due to “bipolar nutrition”. second, normal sensibility is maintained. third, minimal sacrifice of other tissues as a donor. The authors used the Matev distraction divice to lengthen digits in 2 cases of post-traumatic shortening due to bone resorption and secondary scar contracture. By this method, we were able to maintain sufficient length of the digit so that the results were functionally and aesthetically accertable.

老齡化 人口現象과 老人福祉難 : 광주광역시 사례 조사 연구 Case Study of Kwangju City

김수인,최상훈 조선대학교 국토개발연구소 1996 국토개발연구 Vol.16 No.1

This study investigates the actual conditions of Kwangju city in the age of localization with the issues of the aged problem in facilities, population, management and social awareness of the aging society. It is started with the title of difficulty in old people's welfare with the subject of the change of population and the provision of facilities according to the increase of the aged population. Consequently, it finds eight rhenomena and problems.