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完全高密度化된 液相燒結試片의 液相吸入現象에 미치는 固相粒子크기의 영향
權五鍾,李周翰,姜大甲 慶北大學校 1984 論文集 Vol.38 No.-
The effect of Co grain size on the liquid absorption of completely densified Co-Cu compacts by liquid phase sintering is investigated. The compacts of which composition is 80 wt. % Co-20 wt. % Cu, were prepared by ordinary powder metallurgy techniques. To eliminate pores completely and to vary the average size of solid Co grains, the compacts were sintered at 1250℃ for from 1.5-up to 32 hours. A small pellet of 11 wt. % Co-89 wt. % Cu was put into a small hole drilled at the specimen surface. Then the assembly was annealed at the same temperature for from one up to 17 hours. The pellet melted immediately and formed a liquid pool. The presintered body absorbed liquid from the pool. The smaller the solid grain size, the more liquid was absorbed. The amount of the absorbed liquid also increased with the increase of annealing time. The driving force of liquid absorption is expected to be the tendency of anhedral solid grains to restore spherical shape, of which interfacial free energy is lower.
權五鍾,李周翰 경북대학교 공과대학 1983 工大硏究誌 Vol.12 No.-
A simple geometrical model for the interaction between second phase inclusions and grain boundary is suggested. This model indicates that the attracting force of second phase inclusions increases with the decrease in the dihedral angle of inclusions formed at grain boundary. The "joining angle" of grain boundary at which the attracting force shows the maximum value increases with the decrease in dihedral angle, too. Consequently, the maximum average grain size during grain growth is expected to be smaller with smaller dihedral angle.
( Dan Bi Lee ),( Young Hwa Chung ),( Sae Hwan Lee ),( Yoon Seon Lee ),( Don Lee ),( Jeong Eun Hwang ),( Kang Mo Kim ),( Young Suk Lim ),( Han Chu Lee ),( Eun Sil Yu ),( Young Sang Lee ),( Dong Jin Suh 대한소화기학회 2007 Gut and Liver Vol.1 No.1
Background/Aims: The authors examined whether the response to interferon (IFN) therapy can affect the development of hepatocellular carcinoma (HCC) in chronic hepatitis B (CHB) patients. Methods: Out of 353 biopsy-proven CHB patients, 229 (65%) were treated with IFN-α for 6 to 12 months. They were followed for a median period of 75 months (range, 6-120). In patients treated with IFN, biochemical and virologic responses were evaluated at the end of treatment (EOT). The cumulative incidence rates of HCC were calculated and analyzed in relation to baseline characteristics as well as biochemical and virologic responses to IFN therapy. Results: The overall cumulative incidence of HCC was 0%, 0.8%, 3.7% and 5.5% at 3, 5, 7 and 8 years, respectively. Age, serum AFP levels and the stage of fibrosis were significantly associated with the occurrence of HCC. As a whole, IFN therapy did not affect the occurrence of HCC. Among the patients treated with IFN, biochemical responders had low HCC incidence rates compared with non-responders (p=0.018). However, the HCC incidence rates of virologic responders were not different from non-responders (p=0.203). Conclusions: Biochemical rather than virologic response to IFN therapy may be more closely associated with decrease of HCC incidence in CHB patients. (Gut and Liver 2007;1:49-55)
Rituximab treatment for autoimmune limbic encephalitis in an institutional cohort
Lee, Woo-Jin,Lee, Soon-Tae,Byun, Jung-Ick,Sunwoo, Jun-Sang,Kim, Tae-Joon,Lim, Jung-Ah,Moon, Jangsup,Lee, Han Sang,Shin, Yong-Won,Lee, Keon-Joo,Kim, Soyun,Jung, Keun-Hwa,Jung, Ki-Young,Chu, Kon,Lee, Sa Ovid Technologies (Wolters Kluwer) - American Acad 2016 Neurology Vol.86 No.18
<P>Objective: To determine efficacy and safety of rituximab treatment as a second-line immunotherapy treatment for autoimmune limbic encephalitis (ALE) and to determine factors associated with functional improvement and favorable outcome following rituximab treatment. Methods: We recruited 80 patients with ALE who were treated with rituximab as a second-line immunotherapy from the Korea Autoimmune Synaptic and Paraneoplastic Encephalitis Registry and reviewed 81 patients without rituximab as a control. We grouped patients according to the detection or type of antibodies; in addition, we evaluated clinical, laboratory, first-line immunotherapy, and rituximab treatment profiles and defined main outcomes as improvements on the modified Rankin Scale (mRS) score and a favorable mRS score (0-2) at the last follow-up. Results: Functional improvement occurred more frequently in the rituximab group compared to the control group. In the rituximab group, 30 (37.5%) patients had synaptic autoantibodies, 15 (18.8%) in the paraneoplastic autoantibodies, and 35 (43.8%) were antibody-negative. The effect of rituximab was the same regardless of autoantibody status. Additional monthly rituximab therapy and partial response to first-line immunotherapies were associated with mRS score improvements, as well as favorable mRS scores. mRS scores of 4-6 as the worst neurologic status predicted an unfavorable mRS score. There were no reported serious infusion-related or infectious adverse effects of rituximab. Conclusions: Rituximab is effective and safe as a second-line immunotherapy for ALE, regardless of autoantibody status. Additional monthly rituximab therapy might potentiate the efficacy of rituximab. Classification of evidence: This study provides Class IV evidence that rituximab improves mRS scores for patients with autoimmune limbic encephalitis who fail first-line therapy.</P>
A new method for monitoring an OLED panel for lighting by sensing the wave-guided light
Han, Jun-Han,Moon, Jaehyun,Shin, Jin-Wook,Joo, Chul Woong,Cho, Doo-Hee,Hwang, Joohyun,Huh, Jin Woo,Chu, Hye Yong,Lee, Jeong-Ik The Korean Infomation Display Society 2012 Journal of information display Vol.13 No.3
In this work, we report on a new monitoring method for an organic light-emitting diode (OLED) panel for lighting by optical sensing of the wave-guided light in the substrate. Using microlens array films, the wave-guided light was extracted into the edge or back side of the panel to be monitored by a photodiode. The luminance of the extracted light was measured as linearly proportional to the front light. Thus, by converting the extracted light into photo voltage, monitoring the luminance change occurring in the OLED is possible. Based on the results and concepts, we have proposed a photodiode-equipped driving circuit which can generate compensated driving current for uniform luminance of OLED panels.