[P177] Angiokeratomas on the nipple associated with enlargement of the ipsilateral breast: A rare lesion in an adolescent boy

( Hyun-bin Kwak ),( Sang-woo Park ),( Su-kyung Park ),( Soo-han Woo ),( Jin Park ),( Seok-kweon Yun ),( Han-uk Kim ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.1

We experienced a rare and interesting case of angiokeratomas localized on the left nipple of an adolescent boy, associated with enlargement of the ipsilateral breast. To the best of our knowledge, this is the first reported case. A 13-year-old Korean boy presented with asymptomatic black papules on his left nipple with easy bleeding on touch. On examination, he had multiple, discrete, smooth red to black papules restricted to the left sided nipple with enlargement of the underlying breast, giving the breast an asymmetric and unnatural appearance. Dermoscopy revealed blood-filled vascular spaces and crusts. Skin biopsy from the lesion showed mild hyperkeratosis, papillomatosis and acanthosis of epidermis with large, numerous, dilated and congested capillaries in the papillary dermis. Ultrasonography breast were done to rule out any vascular anomaly. No mass was observed in either breast. On the basis of clinical findings and histopathology, he was diagnosed as angiokeratoma with unique presentation as an unusual location.

[P175] Pigmented poroma on the axilla

( Hyun-bin Kwak ),( Sang-woo Park ),( Su-kyung Park ),( Soo-han Woo ),( Jin Park ),( Seok-kweon Yun ),( Han-uk Kim ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.1

Eccrine poroma is a relatively uncommon benign adnexal tumor of epithelial cells originating from the terminal ductal portion of the sweat glands that is typically located on palms and soles, although other cutaneous sites can be affected. It is usually nonpigmented, even if a few cases characterized abundant melanin granules and melanocytes have been reported. A 56-year-old woman presented an asymptomatic brown plaque on her axilla which has arisen over the past 10 years. The physical examination showed brown colored plaque 1.0cm in diameter which slightly elevated the skin surface. Dermoscopy revealed some structures resembling seborrheic keratosis. In histopathology, the tumor replaces the epidermis and grows down into the dermis in broad anastomosing bands. There is a sharp demarcation between the keratinocytes of the adjacent epidermis and the monomorphic, slightly smaller cuboidal poroma cells containing dendritic melanocytes and tumor cell melanin deposition. Atypical mitoses, cytologic atypia or other features suggestive of malignant transformation were not seen. A diagnosis of pigmented eccrine poroma was made. Till now, pigmented poroma on the axilla is not reported yet. We show the interesting and rare case of pigmented poroma on the axilla.

[P029] A case of miliary osteoma cutis on face

( Hyun-bin Kwak ),( Soo-han Woo ),( Seok-kweon Yun ),( Han-uk Kim ),( Jin Park ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.1

Miliary osteoma cutis of the face is a rare variant of osteoma cutis that particularly occurs on the face of middle-aged women. Clinically, it presents as multiple skin colored papules and normochromic hardened nodules predominantly, which mimics milia. They cause therapeutic and cosmetic problem especially in women who are usually concerned. A 55-year-old woman presented with asymptomatic multiple papules on her face. She had no known relevant history of any systemic disease or medication. Physical examination revealed multiple scattered flesh colored, 3-5mm sized, hard papules on the forehead, chin, and both cheek. Under the clinical impression of milia, ablative Er-Yag laser was done, but we found crushed chalky materials from the lesion. Histopathologic findings from the lesion showed a fragment of mature bone formation in the dermis. She was finally diagnosed as miliary osteoma cutis.

[P178] Plaque-type blue nevus in a Korean woman

( Hyun-bin Kwak ),( Sang-woo Park ),( Su-kyung Park ),( Soo-han Woo ),( Jin Park ),( Seok-kweon Yun ),( Han-uk Kim ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.1

Plaque-type blue nevus is a rare variant of blue nevus, the precise prognostic significance of which is unknown. We report the unusual and rare case of an uncommon large, agminated blue nevus of the ``plaque type`` in a 23-year-old Korean female. She presented with a large blue plaque, 2.5 x 6cm in size, on the right lower flank. There were spots of various shades of blue on the plaque. The lesion had developed since birth and became more prominent over the past years. The patient had noticed subcutaneous nodules recently. On physical examination, subcutaneous nodules were found on palpation with no pain. No enlargement of the regional lymph nodules was found. Upon dermoscopic examination, the lesion was typified by areas of homogenous, unstructured blue pigmentation, brownish-blue in the center and blue at the periphery. At the periphery, tan pigmentation was noted. A biopsy was taken from the lesions. Elongated melanocytes in the interstices of the collagen with some melanophages were typical of a common blue nevus. No malignant features were found. A diagnosis of plaque-type blue nevus was made.

[P236]A case of Marie-Unna hereditary hypotrichosis

( Hyun-bin Kwak ),( Soo-han Woo ),( Seok-kweon Yun ),( Han-uk Kim ),( Jin Park ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.1

Marie Unna hereditary hypotrichosis (MUHH) is a rare autosomal dominant genodermatosis characterized by progressive non-scarring hair loss starting in early childhood and aggravating at puberty. Recent progress has been made in determining the genetic etiology of MUHH. Until now, two possible loci for MUHH have been mapped to chromosome 8p21 and 1p21.1.1q21.3. Herein, we report a 33-year-old male with characteristic clinical features suggestive of MUHH in previously affected Korean family. A 33-year-old Korean man presented with progressive alopecia of the scalp since childhood. On examination, hair loss patches were prominent on the vertex and occipital margins, with coarseness and kinking in texture. Eyebrows, eyelashes, and axillary and pubic hair were also scanty. There were no other ectodermal and systemic abnormalities. Laboratory findings, including hormone analyses, were within normal limits. Histopathologic examination revealed decreased and miniaturized hair follicles, with trichomalacia and some bizarre hair shaft morphology, pigment clumps in fibrous root sheath. Scanning electron microscopy revealed thickening, longitudinal grooving, twisting, and longitudinal and transverse breakage of the hair shaft. At least three members among three generations of the patient’s family, including her mother and sister displayed similar manifestations. Based on these clinicopathological findings, the patient was diagnosed with MUHH.

[P263] Dermatophytosis of both hands and feet

( Hyun-bin Kwak ),( Sang-woo Park ),( Su-kyung Park ),( Soo-han Woo ),( Jin Park ),( Seok-kweon Yun ),( Han-uk Kim ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.1

Two feet-one hand syndrome is characterized by bilateral tinea pedis with coexistent unilateral tinea manuum. This syndrome is thought to be well known to dermatologists. Bilateral tinea manuum and bilateral tinea pedis, which may be misdiagnosed as other diseases, can be also observed. We experienced a case of bilateral tinea manuum and bilateral tinea pedis in a patient with diabetes mellitus. A 57-year-old man presented for evaluation of hyperkeratotic lesions on the palms and soles. He felt numbness of the fingertips and intermittent tingling sensation on the soles. Skin examination showed hyperkeratotic lesions on the palms and soles. The palmar surfaces of the fingers and the plantar surfaces of the toes showed scaly lesions. He had a history of type 1 diabetes mellitus of 14 years’ duration. Fasting venous plasma glucose concentration and levels of hemoglobin A1c were 332mg/dL and 7.5%, respectively. Hyphae were detected from the palms, soles, and right 3rd toenail. Trichophyton rubrum was isolated from the specimens. He was treated with oral fluconazole (150mg/week) and topical flutrimazole spray and the lesional skin showed improvement.

[P174] Nevus lipomatosus cutaneous superficialis of the sole in an infant

( Hyun-bin Kwak ),( Soo-han Woo ),( Seok-kweon Yun ),( Han-uk Kim ),( Jin Park ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.1

Nevus lipomatosus cutaneous superficialis (NLCS) is a benign hamartomatous condition characterized by the presence of ectopic tissue in the dermis. Clinically, it is classified into two forms; multiple (classic) and solitary. The classic form presents as grouped coalescent soft, smooth plaque or nodules at birth and develops during the first three decades of life. These are most commonly seen in the pelvic girdle, with a predilection for the gluteal region. On the other hand, the solitary form usually presents as a single nodule or papule in adults and can appear at any site, including the lower trunk, knee, axillae, arm, ear or scalp. Herein, we report a rare case of NLCS occurring on the sole of an infant. To the best of our knowledge, this is the second reported case of NLCS on that rare location. A 10-month-old male infant presented with asymptomatic brown soft tumor on his right sole since birth. The infant was delivered via normal spontaneous vaginal delivery with full term. On physical examination, solitary, 0.5×0.5cm sized, soft and nontender, brown nodule was found on the left sole. In addition, he had multiple brown cafe-au-lait-like macules on both extremities. He had no any other systemic or neurological abnormalities and no family history of cutaneous diseases . Histopathologic findings of the tumor revealed grouped and strands of fat cells embedded among the collagen bundles of the dermis, which was compatible with NLCS.

우리나라 산불 발생의 원인별 공간적 특성 분석

곽한빈 ( Han Bin Kwak ),이우균 ( Woo Kyun Lee ),이시영 ( Si Young Lee ),원명수 ( Myung Soo Won ),구교상 ( Kyo Sang Koo ),이병두 ( Byung Doo Lee ),이명보 ( Myung Bo Lee ) 한국산림과학회 2010 한국산림과학회지 Vol.99 No.3

[P176] Angiomyxolipoma of the thumb: Report of a case and review of the literature

( Hyun-bin Kwak ),( Sang-woo Park ),( Su-kyung Park ),( Soo-han Woo ),( Jin Park ),( Seok-kweon Yun ),( Han-uk Kim ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.1

Angiomyxolipoma is a recently described, very rare benign lipomatous tumor which is characterized by proliferation of adipose tissue with a myxoid stroma and multiple thick and thin walled blood vessels. Until now, there is only one case report of angiomyxolipoma on the finger in the literature. A 32-year-old male presented with soft mass on the distal phalanx of the right thumb. He stated that these had been present for seven years and had increased slowly in size. He had no previous history of trauma. The nodule was soft, well defined and movable. The overlying skin was normal. Routine laboratory examinations including complete blood cell count and liver function tests were normal. There was no pain or symptom. Under local anesthesia, the tumor was enucleated by a wedge shaped resection. The lobulated nodule was carefully freed from the surrounding tissues, avoiding damage to the neurovascular bundles. Histopathology report revealed adipocytes with background showing extensive myxoid change and numerous proliferating capillaries. These histologic findings resulted in a final diagnosis of angiomyxolipoma. The patient has been on follow up for 12 months without recurrence.

산불 발생 분포와 지형, 지리, 기상 인자간의 관계 분석

곽한빈(Han-bin Kwak),이우균(Woo-kyun Lee),이시영(Si-young Lee),원명수(Myoung-soo Won),이명보(Myoung-bo Lee),구교상(Kyo-sang Koo) 대한공간정보학회 2008 한국공간정보학회 학술대회 Vol.2008 No.6

우리나라는 산림은 단순림이 많고 밀도가 높기 때문에 산불이 한번 발생하면 대형 산불로 확산될 우려가 크다. 이 때문에 산불 발생을 미리 예측하여 대응할 필요가 있다. 산불 발생 예측을 위해서는 산불 발생에 영향을 미치는 인자와 산불 발생의 관계를 파악하는 것이 중요하다. 본 연구는 1997년부터 2006년까지 발생한 전국에서 발생한 산불의 point data를 이용하였다. 산불 발생 지점의 지형인자와 지리인자, 그리고 산불 발생 당시의 기상인자로 DB를 구축하고 산불 발생과의 관계를 구명하였다. 지형인자 분석은 고도, 방위, 경사에 따른 산불 발생 빈도를 분석하였고, 그 상관관계를 분석하였다. 지리인자 분석에서는 인구밀도, 산불 발생지역의 접근성(도로에 따른 접근성, 대도시와의 거리에 따른 접근성)에 대한 산불 발생의 상관관계를 분석하였다. 기상인자와 산불 발생의 관계는 전국 76개소에서 관측된 온습도 데이터를 보간한 자료와 산불 발생과의 관계를 분석하였다, 기상인자 분석은 산불이 가장 빈번하게 발생하는 3월 하순, 4월 초순, 4월 중순 자료를 평균하여 산불 발생 빈도와의 상관관계를 분석하고 산불 발생 위험지역을 도출하였다. 본 연구를 통해서 각 인자와 산불 발생의 관계를 분석해보았다. 하지만 각 인자간의 관계를 분석하지 못한 것이 한계점이라고 할 수 있다. 차후 연구에서는 각 인자간의 관련성을 분석하고 산불 발생의 원인과 인자간의 구체적인 인과관계를 밝히는 것도 필요할 것으로 보인다.