사용자 인식 스마트 홈 미러

최건영,고성화,김종옥,박은서,김완규,백경동,박동규 순천향대학교 부설 산업기술연구소 2021 순천향 산업기술연구소논문집 Vol.27 No.2

The Internet of Things, the core of the Fourth Industrial Revolution, is growing by incorporating various technologies into various fields. Among them, smart home systems that apply IoT technology to home environments are being actively studied. The home hub market, a means of communication for smart homes, is also developing at the same time. As the home hub market develops, security threats are also increasing accordingly. In this paper, 'Smart Home Mirror' is implemented by combining mirror and IoT technologies so that users can use them to communicate with smart home applications and other devices. To meet security issues, users in it are recognized by using face recognition technology and AES between all data communications in it is applied. The proposed device’s usefulness is approved by implementing it in smart home environments.

Lipopolysaccharide로 활성화된 RAW264.7세포에서 염증반응사이토카인 발현에 대한 Epigallocatechin gallate의 억제효능연구

서은지(Eun Ji Seo),고준(Jun Go),김지은(Ji Eun Kim),고은경(Eun Kyoung Koh),송성화(Sung Hwa Song),성지은(Ji Eun Sung),박찬규(Chan Kyu Park),이현아(Hyun Ah Lee),김동섭(Dong Seob Kim),손홍주(Hong Joo Son),이충열(Cung Yeoul Lee),이희섭(Hee 한국생명과학회 2015 생명과학회지 Vol.25 No.9

Epigallocatechin gallate (EGCG)는 녹차(Camellia sinensis, green tea)에 포함되어 있는 대표적인 카테킨(Catechin)으로, 당뇨(diabetes), 신경퇴행성 질환(neurodegenerative disorders), 암(cancer), 심혈관계 질환(cardiovascular disease), 비만(obesity) 등의 다양한 임상질환에 우수한 치료효과를 나타내는 것으로 알려왔다. 본 연구에서는 EGCG가 LPS (Lipopolysaccaride)로 자극된 RAW264.7 세포의 염증억제과정에서 Nitric oxide (NO)관련인자와 사이토카인 발현에 미치는 영향을 분석하기 위해, NO농도, inducible NO synthase (iNOS) 발현량, TNF-α, IL-1β, IL-6, IL-10 사이토카인의 발현량을 분석하였다. 먼저, EGCG (100-400 μM)를 처리한 Raw264.7 세포에서 특이적인 독성이 나타나지 않음을 확인하였으며, 이후 Raw264.7 세포에 4가지 다른 농도(0.1, 0.5, 1.0, 5.0 ㎍/ml)의 LPS를 처리한 후 MTT분석, NO농도분석, IL-6농도분석을 실시하여, 염증을 유발할 수 있는 최적 LPS 농도를 1 ㎍/ml로 설정하였다. NO농도를 분석한 결과, LPS를 처리한 그룹이 No그룹에 비하여 급속히 증가하여 63 μ㏖/l까지 증가하였으나 400 μM EGCG를 처리한 그룹에서만 68.2% 정도 감소하였으며, 동시에 iNOS 발현 양상은 200, 400 μM EGCG/LPS 처리 그룹에서 각각 12.3%, 17.4% 감소하였다. 또한, 감소비율에는 차이가 있었으나, anti-inflammatory 사이토카인(IL-1β, TNF-α)과 pro-inflammatory 사이토카인(IL-10)의 발현은 EGCG/LPS 처리에 따라 유의적으로 감소하였다. 그러나, IL-6단백질과 mRNA 농도는 Vehicle/LPS 처리 그룹과 EGCG/LPS 처리 그룹에서 유의적인 차이를 나타내지 않았다. 따라서, 본 연구의 결과는 EGCG가 LPS의 자극에 의해 활성화된 Raw264.7 세포를 효과적으로 억제하는 효능을 나타냄을 제시하고 있으며, 이러한 과정에 사이토카인들이 서로 다르게 특이적 반응을 중계함을 제시하고 있다. Epigallocatechin gallate (EGCG), the main catechin in green tea, has been shown to have some beneficial effects against various human diseases, including diabetes, neurodegenerative disorders, cancer, cardiovascular disease and obesity. To investigate the mechanism of the suppressive effects of EGCG on inflammatory response in macrophages, alterations on the levels of nitric oxide (NO) regulatory factors and inflammatory cytokines were measured in lipopolysaccharide (LPS)-activated RAW264.7 cells. No significant toxicity was detected in RAW264.7 cells treated with 100?400 μM EGCG. Moreover, the optimal concentration of LPS was determined to be 1 ㎍/ml based on the results of cell viability assay, NO assay and IL-6 enzyme-linked immunsorbent assay (ELISA). Furthermore, NO levels decreased significantly by 68.2% in the 400 μM EGCG/LPS treated group, while the level of inducible nitric oxide synthase (iNOS) expression decreased by 12-17% in the 200 and 400 μM EGCG/LPS treated group. A significant decrease in transcription of pro-inflammatory cytokines (TNF-α and IL-1β) and anti-inflammatory cytokine (IL-10) was also detected in the EGCG/LPS treated group. However, IL-6 transcript and protein was maintained at a constant level when in the LPS treated group relative to the EGCG/LPS treated group. Overall, these results suggest that the differential regulation of inflammatory cytokines is an important factor influencing the suppressive effects of EGCG against LPS-activated inflammatory response in RAW264.7 cells.

기포유동층 고분자 중합 반응기에서의 슬러그 특성

고은솔 ( Eun Sol Go ),강서영 ( Seo Yeong Kang ),서수빈 ( Su Been Seo ),김형우 ( Hyung Woo Kim ),이시훈 ( See Hoon Lee ) 한국화학공학회 2020 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.58 No.4

고체 입자들이 유체처럼 움직이는 유동층 공정은 에너지 전환 공정뿐만 아니라 범용 고분자 수지의 생산 공정에도 이용되고 있다. 범용 고분자 수지 중의 하나인 LLDPE(Linear low density polyethylene)도 기포 유동층 공정을 통해 전세계에서 생산되고 있다. 입자 크기에 비해 밀도가 낮은 LLDPE 입자들은 고분자 중합 반응을 위해 공급되는 수소에 의해서 유동화된다. 그러나 LLDPE 생산 공정은 기포유동층 공정임에도 불구하고 발생한 슬러그로 인하여 반응에 영향을 끼쳐 공정의 효율 저하를 불러올 수 있다. 이에 본 연구에서는 상용 고분자 반응기를 모사한 pilot 규모의 고분자 합성 반응기(0.38 m l.D., 4.4 m High)와 동일한 시뮬레이션 모델을 구축하여 LLDPE 입자의 유동화 상태를 고찰하였다. 특히 기체 유속(0.45-1.2 m/s), 고체 입자 밀도(900-1900 kg/㎥), 입자 구형도(0.5-1.0), 입자 크기(120-1230 μm)의 변화에 따른 슬러그 특성을 세밀하게 고찰하기 위하여 전산입자유체해석(Computational particle-fluid dynamics, CPFD)을 이용하였다. CPFD를 통해서 일부 실험자들만 고찰할 수 있었던 flat slug의 발생을 시각적으로 구현하였으며 밀도, 구형도, 크기 등의 고체의 물리적 특성을 변화시킴에 따라 슬러그 발생을 저감시킬 수 있음을 확인하였다. Fluidization processes in which solid particles vividly move like gas or liquid have been widely used in various industrial sectors, such as thermochemical energy conversion and polymerization processes for general purpose polymer resins. One of the general purpose polymer resins, LLDPE(Linear low-density polyethylene) resins have been produced in bubbling fluidized bed processes in the world. In a bubbling fluidization polymerization reactors, LLDPE particles with relatively larger particle size and low density are fluidized by hydrogen gas for polymerization reaction. Though LLDPE polymerization reactors are one of bubbling fluidization processes, slugs that have negative impact for reaction exist or occur in these processes. Therefore, the fluidization state of LLDPE particles was investigated in a simulation model similar to a pilot-scale polymerization reactor (0.38 m l.D., 4.4 m High). In particular, the effect of gas velocity (0.45-1.2 m/s), solid density (900-199 kg/㎥), solid sphericity (0.5-1.0), and average particle size (120-1230 μm), on bed height and fluidization state were measured by using a CPFD(Computational particle-fluid dynamics) method. With CPFD analysis, the occurrence of a flat slug was visualized. Also, the change in particle properties, such as particle density, sphericity, and size, could reduce the occurrence of slug and bed expansion.

An ANKRD11 exonic deletion accompanied by a congenital megacolon in an infant with KBG syndrome

Seo, Go Hun,Oh, Arum,Kang, Minji,Kim, Eun Na,Jang, Ja-Hyun,Kim, Dae Yeon,Kim, Kyung Mo,Yoo, Han-Wook,Lee, Beom Hee Korean Society of Medical Genetics and Genomics 2019 대한의학유전학회지 Vol.16 No.1

KBG syndrome is an autosomal dominant syndrome presenting with macrodontia, distinctive facial features, skeletal anomalies, and neurological problems caused by mutations in the ankyrin repeat domain 11 (ANKRD11) gene. The diagnosis of KBG is difficult in very young infants as the characteristic macrodontia and typical facial features are not obvious. The youngest patient diagnosed to date was almost one year of age. We here describe a 2-month-old Korean boy with distinctive craniofacial features but without any evidence of macrodontia due to his very early age. He also had a congenital megacolon without ganglion cells in the rectum. A de novo deletion of exons 5-9 of the ANKRD11 gene was identified in this patient by exome sequencing and real-time genomic polymerase chain reaction. As ANKRD11 is involved in the development of myenteric plexus, a bowel movement disorder including a congenital megacolon is not surprising in a patient with KBG syndrome and has possibly been overlooked in past cases.

An ANKRD11 exonic deletion accompanied by a congenital megacolon in an infant with KBG syndrome

Go Hun Seo,Arum Oh,Minji Kang,Eun Na Kim,Ja-Hyun Jang,Dae Yeon Kim,Kyung Mo Kim,Han-Wook Yoo,Beom Hee Lee 대한의학유전학회 2019 대한의학유전학회지 Vol.16 No.1

KBG syndrome is an autosomal dominant syndrome presenting with macrodontia, distinctive facial features, skeletal anoma-lies, and neurological problems caused by mutations in the ankyrin repeat domain 11 (ANKRD11) gene. The diagnosis of KBG is difἀcult in very young infants as the characteristic macrodontia and typical facial features are not obvious. The youngest patient diagnosed to date was almost one year of age. We here describe a 2-month-old Korean boy with distinctive craniofa-cial features but without any evidence of macrodontia due to his very early age. He also had a congenital megacolon without ganglion cells in the rectum. A de novo deletion of exons 5-9 of the ANKRD11 gene was identiἀed in this patient by exome sequencing and real-time genomic polymerase chain reaction. As ANKRD11 is involved in the development of myenteric plexus, a bowel movement disorder including a congenital megacolon is not surprising in a patient with KBG syndrome and has possibly been overlooked in past cases.

Enzymatic Synthesis and Characterization of Hydroquinone Galactoside using Kluyveromyces lactis Lactase

Go-Eun Kim,Eun-Seong Seo,Sun-Hwa Jung,Jaeho Cha,Eui-Joong Kim,Doman Kim 한국당과학회 2010 한국당과학회 학술대회 Vol.2010 No.1

Hydroquinone galactoside (HQ-Gal) as a potential skin whitening agent was synthesized by the reaction of lactase (β-galactosidase) from Kluyveromyces lactis, Aspergillus oryzae, Bacillus circulans and Thermus sp. with lactose as a donor and HQ as an acceptor. Among these lactases, the acceptor reaction involving HQ and lactose with K.lactis lactase showed higher conversion ratio to HQ-Gal(60.27%). HQ-Gal was purified using butanol partitioning and silica-gel column chromatography. The structure of the purified HQ-Gal was determined by nuclear magnetic resonance and the ionic product was observed at m/z 295(C12H16O7Na)+ using matrix assisted laser desorption ionization time-of-flight mass spectrometry. HQ-Gal was identified as 4-hydroxyphenyl-β-D-galactopyranoside. The optimum conditions for HQ-Gal synthesis by K.lactis determined using response surface methodology were 50 mM HQ, 60 mM lactose, and 20 U mL-1 lactase. These conditions produced a yield of 2.01 g L-1 HQ-Gal. The half maximal inhibitory concentration (IC50) of diphenylpicryl-hydrazyl radical scavenging activity was 3.31 mM indicating a similar anti-oxidant activity compared to β-arbutin(IC50=3.95 mM). The Ki value of HQ-Gal(0.75 mM) against tyrosinase was smaller than that of β-arbutin (Ki=1.97 mM),indicating superiority as an inhibitor.

Enzymatic Synthesis and Applications of Hydroquinone Glucoside using Leuconostoc mesenteroides Dextransucrase

Eun-Seong SEO,Go-Eun KIM,Jin KANG,Sun-Hwa JUNG 한국생물공학회 2010 한국생물공학회 학술대회 Vol.2010 No.10

Metastatic cancer of the mandible: a case report (초)

( Go Eun Seo ),( Ji A Jeung ),( Sang Jun Park ),( Soo Woon Lee ) 대한악안면성형재건외과학회 2010 Maxillofacial Plastic Reconstructive Surgery Vol.32 No.2s

낙동강 홍수 범람시 우포늪의 홍수저류량과 수질정화능 평가

이은주 ( Eun Ju Lee ),김주원 ( Ju Won Kim ),김고운 ( Go Eun Kim ),서성은 ( Seong Eun Seo ),조경제 ( Kyung Je Cho ) 한국물환경학회 ( 구 한국수질보전학회 ) 2005 공동 추계학술발표회 Vol.2005 No.-

상속인인 보험수익자에 관한 고찰 : 보험수익자의 결격사유와 보험금의 분배를 중심으로

서고은(Seo, Go Eun) 한국보험법학회 2020 보험법연구 Vol.14 No.1

타인을 위한 생명보험은 기대가능수명이 현격히 연장됨에 따라 생활보장수단에 대한 관심 높아지고 있는 현대사회에서 특히 주목받고 있는 보험계약이라 할 수 있다. 타인을 위한 생명보험계약이 보험사고 발생 후 유족에 대한 보호를 주요기능으로 함에 따라 보험계약자는 대개 본인 및 피보험자의 상속인을 보험수익자로 지정·변경한다. 또한 보험계약자가 보험수익자 지정·변경권이나 재지정권을 행사하기 전 사망하거나 보험사고가 발생하면 상법 제733조에 따라 피보험자나 보험수익자의 상속인이 보험수익자가 된다. 이처럼 타인을 위한 생명보험계약의 보험수익자는 ‘보험계약자 등(보험계약자 측)’의 상속인이 되는 경우가 많다. 이러한 경우 보험수익자는 상속인의 지위와 보험수익자의 지위를 겸하게 된다. 이와 같은 상속인인 보험수익자와 관련하여서는 크게 두 가지의 주요 논점이 제기된다. 첫 번째는 상속인인 보험수익자가 피보험자의 고의 살해 이외의 민법상 상속결격사유를 행한 경우 보험수익자의 지위 유지 여부와 그 효과에 대한 논점이다. 두 번째는 상속인이 보험수익자가 된다면 그 수가 수인인 경우가 많음에 따라 보험사고 발생 시 보험금의 분배방식에 대한 논점이다. 상속인인 보험수익자에 대하여 이러한 논점이 제기되는 근본적인 이유는 상법상 이에 관한 명문의 규정이 마련되어 있지 않기 때문일 것이다. Life insurance for other person is an insurance contract that is particularly noteworthy in modern society, where interest in means of living is increasing. Life insurance for other person shall be the main function of protecting the bereaved family after an insurance accident occurs. Consequently, the policyholder usually designates and change the heirs of the policyholder and the insured as the beneficiary of the insurance contract. In addition, in accordance with Article 733 of the Commercial Law, the heirs of the insured and the beneficiary becomes the beneficiary of the insurance contract if the policyholder dies before exercising the right to designate and change the beneficiary or reassign the beneficiary. As such, the beneficiaries of Life insurance for other person often become the heirs of ‘the policyholder and others . In such a case, the beneficiary will also have the status of the heir and the status of the beneficiary. There are two main issues that arise with the beneficiary of the insurance contract as heir. The first is the issue of whether to maintain the status of the beneficiary and its effect if the beneficiary of the insurance contract as heir has committed a reason for disqualification prescribed by civil law except for the deliberate murder to the insured. The second is the issue of the way insurance money is distributed to the beneficiaries of the insurance contract as heir in the event of an insurance accident. The fundamental reason for this issue to be raised for the beneficiary of the insurance contract as heir may be that the commercial law does not have a stipulation in the statement. In this paper, we will consider the points raised earlier on the basis of foreign legislations and related theories and a judicial precedents. Based on this, the amendments of Commercial Law are proposed to provide the ultimate solution to the issues.