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      • 휴대용 근적외분광분석기를 이용한 유탕면의 수분 함량 측정 : Infrared(NIR) System

        임현량,김도형,우영아,김효진 동덕여자대학교 종합약학연구소 2002 동덕약학연구지 Vol.6 No.-

        This experiment was carried out to determine non-destructively water content in a intact fried noodle in oil by portable near-infrared system. Water content was ranged from 0 to 14.3w/w% and the near infrared (NIR) measurements were made on 70 intact samples over the spectral range 1100-1750nm. We found the variation of absorbance band due to OH vibration of water in the noodles depending on the concentration change around 1450nm in the second derivatives spectra. Partial least squares(PLS) regression models were set up using a calibration set(42 E.A.) and a validation set(28 E.A.) between the NIR response and value from loss on dry. Various pretreatments of the spectra were examined: the smallest stnadard error of prediction(0.35%) was obtained using autoscaling spectra over 1100-1700nm. 10 factors were required for the PLS model to give a good relationship between the spectral information and the noodle water content. In order to validate the developed calibration model, routine analyses were performed using other intact noodles. Water contents from the NIR calibration model were compared with the values from loss on dry and the results showed good correlation with those of loss on dry. This study showed that the rapid and non-destructive determination of water content in a intact fried noodle in oil was successfully performed by portable NIR system.

      • 복숭아나무 硬枝揷木時 揷木 用土와 基間이 發根과 圃場活着에 미치는 영향

        林敬鎬,林炯基,金道翊,金月洙,鄭淳柱 全南大學校 農業科學技術硏究所 1998 農業科學技術硏究 Vol.33 No.-

        복숭아나무 경지삽목 번식에 있어서 삽목 용토와 기간 및 삽수내 저장 양분 함량 변화 등이 발근과 포장 활착에 미치는 영향을 구명하였다. 삽목 용토는 vermiculite가 peat pellets 岩線보다 발근율, 발근수와 발근장 및 포장 활착율 등에 있어서 가장 좋은 효과를 나타냈다. 삽목 기간은 35일에서 55일로 기간이 길어질수록 발근율이 높고 뿌리 발달이 좋아졌으나, 포장 활착율은 삽수내전탄수화물과 전당 등 전당 등 저장양분 소비가 많아 삽목 기간이 짧은 35일에서 높았다. 특히 이들 양분 중에서 sucrose의 소비가 가장 많았다. 포장에서 활착후 수고, 간경 등 생육은 모든 처리에서 수고 136㎝, 간경 22.9㎜ 이상으로 삽목 당년에 우량묘가 생산되었다. This experiment was studied to examine the effect of cutting media and duration on rooting and transplanting using hardwood cutting of 'Sunaga Wase' peach to establish mass production system of rooted cutting. In cutting media, vermiculite showed higher root growth than peat pellets and rock-wool on rooting, root number, root length, and survival in field. The longer cutting duration was from 35 to 55 days, the better rooting and root growth obtained. But the transplanting was the best at 35 days, because it held enough storage nutrient including carbohydrate and sugar which were consumed in cutting stem tissue of 'Sunaga Wase' peach during hardwood cutting. Especially, among these nutrients, sucrose showed the highest consumption. After transplanting of rooted cutting to field, tree height and diameter of ' Sunaga Wase' peach was 136㎝ and 22.9㎜, respectively. therefore it could product the best quality of rooted cutting.

      • Irbesartan과 Lercanidipine의 병용요법이 고혈압 및 혈관재형성에 미치는 효과

        이도형, 임태완, 조은지, 박현수, 정상혁, 한주희, 병창선 충남대학교 약학대학 의약품개발연구소 2017 藥學論文集 Vol.32 No.-

        Hypertension is one of the major risk factor for cardiovascular disease and can lead to or make worse many complications, heart disease, atherosclerosis and diabetes. Thus, managing blood pressure effec tively using therapeutic drugs such as angiotensin II receptor blocker (ARB) and Ca2+ channel blocker (CCB) can be prevent other complications. Therefore, we investigated the synergistic effect of these two drugs, ir besartan and lercanidipine, for antihypertension, cardioprotection and antidiabetes. Irbesartan (28.74 mg/kg, 14.37 mg/kg) or lercanidipine (1.92 mg/kg, 0.96 mg/kg) alone or combination was administered to sponta-neously hypertensive rats (SHRs) and C57BL/6 mice. A two-week treatment of combination with irbesartan and lercanidipine significantly attenuated systolic blood pressure (SBP) and mean arterial pressure (MAP) compared with monotherapy. Futhermore. the combination therapy protected myocardial ischemia reperfusion injury more effectively than monotherapy. In vascular remodeling, combination therapy significantly diminished cuff -induced neointima formation and reduced serum -indllced vascular smooth muscle cells (VSMCs) pro-liferation compared with monotherapy. However, combination therapy had no significant synergistic effect of blood glucose regulation. Taken together, present study suggest that the combination therapy of irbesartan and lercanidipine may be more effective therapeutic strategy for the treatment of hypertension and related complications, myocardial infarction and arterial restenosis than monotherapy

      • 침 치료가 오십견(五十肩) 환자의 적외선 체열촬영에 미치는 영향

        김건형,이로민,남동우,김종인,임사비나,이두익,최도영,이윤호,이재동 경희대학교 동서의학연구소 2006 東西醫學硏究所 論文集 Vol.2006 No.-

        Objectives : To observe the effect of acupuncture treatment on Digital Infrared Thermographic Imaging(DITI) in frozen shoulder patients. Methods : 17 voluntary patients received acupuncture treatment on LI15, TE14, GB21 and Master Dong's acupuncture points, Shin-gwanand Gyun-joong, twice a week for 4 weeks. The patients were instructed to practice self exercise during their daily lives. Evaluations were made before treatment, after 1 week of treatment, after 2 weeks, 3 weeks and after 4 weeks of treatment. Constant Shoulder Assessment(CSA), Shoulder Pain and Disability Index(SPADI), Range of Motion(ROM) and the patient's satisfaction concerning the treatment was measured by Visual Analogue Scale(VAS). DITI was measured before treatment and after 4weeks of treatment. The obtained data was analyzed. Results : CSA, SPADI, VAS, adduction and extension showed significant(p<0.05) improvement. Abduction and flexion both improved after 4 weeks of treatment, but the improvement was statistically insignificant(p>0.05). DITI showed improvement but the improvement was insignificant(p>0.05). Conclusion : 4 weeks of acupuncture treatment significantly improved CSA, SPADI, VAS, adduction and extension in frozen shoulder patients(p<0.05). The improvement of abduction and flexion after 4 weeks of acupuncture treatment was insignificant(p>0.05). DITI results improved after 4 weeks of acupuncture treatment. But the change of thermal difference was insignificant(p>0.05).

      • KCI등재후보

        위암수술 환자에서의 cp 개발과 cp적용에 따른 질 향상 활동에 관한 연구

        임은주,황순휘,박도중,하광일,배현주,김형호 한국의료QA학회 2006 한국의료질향상학회지 Vol.13 No.2

        Background : In an era of increasing medical costs, safe reduction in postoperative stay has become a major focus to optimize utilization of healthcare resources. The authors aimed to evaluate the clinical significance of the critical pathway(CP) for gastrectomy patients by implementing standardized postoperative management and electronic medical records. Method : From August 2006 to April 2007, critical pathways were introduced to inpatients and outpatients with gastric cancer. 60 consecutive patients undergoing distal gastrectomy were randomly divided into two groups; 30 CP group(A) and 30 non-CP group(B). Simultaneously, we also retrospectively reviewed the records of 438 patients(C:control group) who were able to be enrolled in CP program. We compared group(A) with (B), (C) in terms of hospital stay, complication rate, use of antibiotics and hospital costs. Patient satisfaction was surveyed by questionnaires. Result : There was no significant demographic difference between group(A) and (B). Of 30 patients in group(A), 5 drop-outs and 14 variances occurred. The mean postoperative hospital stays(Laparoscopy-assisted distal gastrectomy: LADG/Open distal gastrectomy: ODG) were 7.6/10.5 days for the group(A), 8.9/12.7 days for the group(B) and 12.6/14.5 days for the group(C) (p=0.02 in LADG). The total hospital cost of group(A) had a tendency to be less than that of group(B) and the amount of hospital cost per day in group(A) was significantly higher than that in group(B). The usage rates of the first generation antibiotics were 73.33%, 63.33%, and 59.2% in group(A), (B), and (C), respectively. Patients’ satisfaction had a tendency to be higher in the CP group than non-CP group. Conclusion : The mean hospital stay in LADG patients was shortened meaningfully and hospital cost per day was enlarged after introduction of clinical pathway. It is necessary to apply a number of patients to the critical pathway and to make an effort to reduce the variation and drop-out rates.

      • SCOPUSKCI등재

        CASE REPORT : An Unusual Case of Superior Vena Cava Syndrome Caused by the Intravascular Invasion of an Invasive Thymoma

        ( Hyung Joon Kim ),( Sun Young Cho ),( Woo Hee Cho ),( Do Hyun Lee ),( Do Hyoung Lim ),( Pil Won Seo ),( Mi Hyun Park ),( Wonae Lee ),( Jai Hyuen Lee ),( Doh Hyung Kim ) 대한결핵 및 호흡기학회 2013 Tuberculosis and Respiratory Diseases Vol.75 No.5

        Superior vena cava syndrome (SVCS) is usually caused by extrinsic compression or invasion of the superior vena cava (SVC) by malignant tumors involving mediastinal structures. Although thymomas are well-known causes of SVCS, cases of SVCS caused by malignant thymomas protruding into adjacent vessels draining the SVC with thrombosis have been very rarely reported worldwide. We experienced a 39-year-old female patient with SVCS that developed after the direct invasion of the left brachiocephalic vein (LBCV) and SVC by an anterior mediastinal mass with a high maximum standardized uptake value on the chest computed tomography (CT) and positron emission tomography-CT. Based on these results, she underwent en bloc resection of the tumor, including removal of the involved vessels, and was eventually diagnosed as having a type B2 thymoma permeating into the LBCV and SVC. We present this case as a very rare form of SVCS caused by an invasive thymoma.

      • KCI등재

        Polychlorinated Biphenyl의 작물-토양간 흡수 이행성

        임도형(Do-Hyung Lim),임다솜(Da-Som Lim),금영수(Young-Soo Keum) 한국농약과학회 2016 농약과학회지 Vol.20 No.3

        Polychlorinated biphenyls (PCBs) are ubiquitous environmental contaminants, found in the many environments. PCBs exerts various toxicological effects, including endocrine-disrupting activity. Most researches with these toxicants performed with soil matrix with mixtures of congeners, namely Aroclor, while the biological activities have been tested with animals. However, studies with pure congeners are limited. In this study, 5 congeners were synthesized and their fates (bioaccumulation, degradation, kinetics) were studied in carrot-soil system. The soil half-lives of biphenyl, PCB-1, PCB-3, PCB-77, and PCB-126 were 20.2, 16.0, 11.6, 46.5, 198.0 days, respectively. In general, the longer half-lives were observed with the higher hydrophoicity of PCBs. Times, required for maxium accumulation of PCBs in carrot (Tmax) were 10-20 days for most congeners and the concentrations were 0.4-2.6 mg/kg. The concentrations of PCBs in carrot were kept as constant after Tmax, except PCB-126. The concentration ratio between carrot and soil after 90 days of treatment were 1.7, 8.1, 1.9, 1.8, and 5.9 for biphenyl, PCB-1, PCB-3, PCB-77, and PCB-126. Because of the increase of biomass, the total residual amount of PCBs in carrots however, increased till the end of experiment. The portions of PCB-126 in carrot were 1.1% of the soil residues at 90 days after planting.

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