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      • 나팔 형태의 공간 모델링을 기반으로 한 객체 파노라마 생성 방법

        정정일 경원대학교 일반대학원 2011 국내석사

        RANK : 1855

        배경 파노라마와 같은 경우에는 가상공간 내에서 다양한 주변 정보를 사용자에게 제공해 줄 수 있는 반면에, 가상공간 내 특정 객체에 대해서는 극히 단편적인 정보들만을 포함하고 있기 때문에, 사용자가 관찰하고자 하는 객체에 대한 영상정보를 제공할 수 없다. 따라서 이러한 배경 파노라마의 단점을 보완하여 가상공간 내에서 사용자에게 특정 객체에 대해 현장감 있는 영상정보를 제공하기 위해 객체를 중심으로 파노라마 영상을 생성할 수 있는 객체 파노라마 기법들이 연구 중이다. 그러나 현재까지의 객체 파노라마를 위한 공간 모델링은 단순히 특정한 촬영 공간 내에서 카메라를 수직회전 함과 함께 객체를 회전해가며 영상을 촬영한 후, 이를 고정된 사용자의 시점에 맞추어 순차적으로 보여주는 수준에 머물러 있다. 이러한 객체 파노라마 생성 방법은 단순한 소형 모델에 대해서는 손쉽게 파노라마를 생성할 수 있지만, 석탑 및 박물관의 전시품과 같은 대형 모델에 대해서는 촬영을 위한 공간을 설치하기가 어렵고, 특히 모델 자체를 회전시킬 수가 없기 때문에 객체 파노라마를 생성할 수가 없다. 따라서 본 논문에서는 일반적인 촬영 환경에서 모델(model)을 관찰하는 카메라의 기하학적 변환을 고려하여 모델의 크기와 관계없이 현장감 있는 객체 파노라마를 생성하는 방법을 제안한다. 제안한 방법에서는 먼저 대상 모델을 중심으로 한 카메라의 수직회전 및 수평회전 이동과 같은 기하학적 변환을 기반으로 나팔 형태의 파노라마 공간을 모델링한다. 다음으로 생성한 파노라마 공간에 영상들을 정렬 및 정합하여 매핑(mapping) 시킴으로써 객체 파노라마를 생성한다. 제안한 방법의 성능 평가를 위하여 일반적으로 특수 장비 없이는 객체 파노라마를 생성하기 어려운 대형 모델을 대상으로 영상을 촬영하여 실험을 진행하였다. 결과적으로 제안한 방법으로는 주로 특수 촬영 공간 내에서 생성해야 하던 객체 파노라마를 모델의 크기에 관계없이 일반적인 촬영 공간 내에서도 효과적으로 생성할 수 있었다.

      • 전자신용보증에 의한 학자금대출 유동화의 법적 고찰

        정정일 경희대학교 국제법무대학원 2008 국내석사

        RANK : 1855

        The Student Loan Credit Guarantee Fund (the "Fund") was established in July 2005 and started to provide guarantee services in the form of government guarantee to the financial companies which are about to grant student loans to collegians in financial need. Initially the government subsidized the interest gap between the real market rate and the nominal interest rate applied to the student loans, but saw the limit of its funding. At this juncture, the Korea Housing Finance Corporation (KHFC), a public enterprise in Korea, securitized series of student loan-backed securities (SLBS) from a pool of the student loans. By selling the SLBS bonds to investors, KHFC eventually makes available loanable funds to students. At the same time, the Fund is operated by KHFC entrusted by the government for the purpose of efficient guarantee of student loans. This whole process is called the "government-guaranteed student loan system" in Korea. Under this new student loan system, government funds are siphoned to the source of the Fund, and the student loan guarantees increase up to 20 times the total amount of the Fund at lesser cost than before. The Fund has covered in general the tuitions and living expenses of students. Thus, during the past years, the Fund has contributed to the enhanced financial availability given to undergraduate and graduate students by ensuring the debt service and stability of student loans. KHFC usually enters into agreements with the financial companies in advance in the following manner: - When the financial institutions lend student loans to students, then student loans are assigned to KHFC through true sale; and - The credit guarantee is conducted electronically on the Internet in no need of face-to-face transactions at all. Accordingly, the KHFC regularly securitizes the homogeneous pool of student loans in the capital market. This whole process is an advanced student loan financing scheme that allows for extension of larger student loans to a greater number of students without additional funding requirements. The purpose of this study is to explore what the electronic credit guarantee of the Fund is and how the securitization of the student loan is conducted in legal terms. The first chapter is the purpose, limits and method of this study. Chapter 2 explains the changes and improvements achieved in the past with regard to the student loan system in the public sector. Chapter 3 summarizes the process and mechanism of the electronic credit guarantee of student loan, while Chapter 4 explains the mechanism how to securitize student loans. Chapter 5 examines the current status and possible structural improvement, and the results of the government-guaranteed student loan system. Chapter 6 analyzes the legal aspects - the legal nature of agreements, contracting parties, general terms and admissibility of the electronic credit guarantee for student loans. Chapter 7 discusses the legal aspects of the student loan securitization based upon the KHFC Act. Chapter 8 concludes this study as explained above. The electronic credit guarantee for the student loans provided by the Fund is an electronic transaction with financial nature. The Fund and students, who take part in the process of the electronic credit guarantee, enter into an electronic transaction agreement, with electronic signatures certified by public certification agencies. In this regard, the electronic contractual terms of the electronic credit guarantee are subject to the Act on the Regulation of General Terms. The electronic credit guarantee message, which is issued and sent by the Fund, is ensured by the Framework Act on Electronic Transactions for the effect of document formality and admissibility in civil proceedings. In order to improve the government-guaranteed student loan system, this study is focused on the following suggestions: - For the effective lowering of student loan interest rates, it is necessary for the Fund to acquire the subordinated bonds in connection with the securitization of SLBS; - When KHFC entrusts student loan assets to itself as a self-trustee, the mandatory requirement for a true sale in accordance with the ABS Act or the KHFC Act should be modified in line with the trust regime; - The "risk" as provided in Item 4 Article 25 of the KHFC Act is so broad that it should be clearly defined as the risk including the assigner's responsibility for the defected rights; - The KHFC Act should be amended to empower KHFC to issue a bond type of SLBB so as to diversify the securitization method and save the funding cost; and - KHFC should be allowed to buy and hold student loan portfolios as a pool for the timely issuance of SLBS.

      • 建設災害의 原因과 豫防對策에 관한 硏究

        정정일 성균관대학교 행정대학원 2004 국내석사

        RANK : 1855

        There is none who deny that the construction industry of this country has become king sized and heavier to be world standard in the technical aspects to contribute big to the development of the national economy owing to the rapid development of the national economy. Though it has weighed heavy in the economic development, we could not overlook the fact that on its back side there has been many of the human sacrifice and lots of the property loss due to many of the unexpected disasters. These are to be considered as the results of the life despise tendency and the negligence of the safety spreading in the whole society and the lack of the basic measures. The construction disaster takes the labourer's life and the property at once and threatens our life itself. As well as the economic development, we have the right to live happy living and lots of labourers who dreams the happy living to work hard could never be the sacrifice of the industrial disaster. The industrial disaster itself is the personal unluck and causes the big national loss as well and has to be prevented. While studying, the reporter has read out that in spite of sincere efforts, there still has been lots of humane and property losses in many of the construction sites and these facts of the heavier industrial disaster rates to the developed nations have resulted from the direct and indirect results including the unawareness and the un-safety works and aspect of the labourer themselves and more over the lack of the systematic measures in addition to the managerial negligence. Thus, the study aims to the prevention of the construction disaster and studies the measures to present the preventive data helping the disaster prevention. Considering above problems, the study compares to analyze the construction disaster of this country to the other industries and to that of the developed foreign nations and induces to summarize to below conclusion. First, the preventive measure to the material based disaster are to perform precisely the checking up before commencing work and regular inspection over the whole equipment, setting up of the safety installation to the equipment, checking up of the oddity of the equipment, placing the safety guards to prohibit the reach of the non-workers near to the working area. Further to the temporal facilities, sure to prepare the safety measures against the bad weathers and install the protection fince and the safety net to check the normality daily. The construction machine operation should be manned to operate with the operator with enough mentality and personality to prevent potential disaster factors previously. Second, in performing works, would-be the direct causations in the material factor and in the human factor that are the unsafe state and action should be removed previously planning the practical schedule. In addition, should completely practice the safety education and should make the adequate site rules fit and should avoid the managerial defect. Also, to minimize the technical errors which have many of the unexpected possibility of danger, should gather all who are concerned to review fully. Third, should improve special safety education for the newly placed and the poor experienced along with the senior workers practically and for the top manager, should have him to take full responsibility and have him to be habitual the safety check-up and should him keep to manage continuously the practice of the preventative measures. Fourth, systematically, there requires the change or the complement of the tender system which may cause the contraction of the work period, cost saving and excessive competition and should select good corporative enterprises with enough financial capacity who will be able to perform the safety management to transact fairy with.

      • 블루투스와 무선랜으로 구성된 하이브리드 네트워크에서 멀티캐스트 라우팅 프로토콜의 설계 및 구현

        정정일 광운대학교 대학원 2002 국내석사

        RANK : 1855

        본 논문에서는 블루투스와 W-LAN으로 구성된 하이브리드 네트워크에서 멀티캐스트 프로토콜인 ODMRP를 이용할 경우 발생하는 문제점을 해결하기 위하여 블루투스와 W-LAN이 함께 동작할 수 있는 듀얼모드 노드를 제안하고 Adaptation Layer를 구현하였다. IP 어드레스를 이용할 수 있도록 블루투스 엑티브 멤버 어드레스와 맵핑하는 피코넷 맵핑 테이블을 추가하였으며, 피코넷에서 사용되는 JOIN REQUEST 패킷과 JOIN MEMBER 패킷을 기존의 ODMRP에 추가하여 컨트롤 패킷의 브로드캐스팅을 줄일 수 있도록 하였다. 하이브리드 네트워크 환경에서 수정된 멀티캐스트 프로토콜을 제안하며, 구현 및 실험을 통해 기존의 프로토콜과 비교하여 약 3.5배 향상된 성능을 보이는 것을 알 수 있다.

      • 普通去來約款의 規制에 관한 硏究 : 消費者保護를 中心으로

        정정일 京畿大學校 大學院 1997 국내석사

        RANK : 1855

        約款은 大量生産, 大量販賣, 大量消費로 特徵 되어지는 現代社會에서 보다 合理的인 契約去來를 위한 하나의 考案이다. 따라서 約款은 各種去來를 편하게 하기 위한 道具 또는 手段의 성격을 가진다고 할 수 있다. 그런데 그 約款으로 인해 一方 去來當事者에게 法的 利益의 犧牲이 要求되거나 讓步가 강요된다면 그것은 當事者間의 衡平과 正義에 적합할 수 있도록 適當한 規制가 필요하게 된다. 約款은 消費者生活을 위한 去來關係의 주요 媒介體로서 人類가 契約自由를 알면서 성장하기 시작하여 資本主義의 고도발달에 따른 大量生産·大規模去來의 형성과 함께 눈부시게 발전해 왔다. 이제 約款은 現代를 살아가는 우리 삶 곳곳 어디에나 존재하고 있다. 約款의 根源은 契約留保(法律留保)에 있다고 하는데 이는 不特定 多數의 契約相對方(顧客, 消費者)을 대상으로 일정 종류의 去來에 劃一的으로 適用하기 위하여 事業者에 의해 미리 마련된 契約條件으로서 顧客이 그 契約에 의하지 않는다는 意思表示를 하지 않는 한 그에 따르느 것으로 이해되고 있다. 한편 企業은 자신의 利潤確保를 消費者利益보다 우선하여 고려하는 것이 一般的이기 때문에 約款條項이 企業의 利益奉仕를 위해 消費者利益의 犧牲을 內容으로 작성될 可能性이 높다. 더구나 現代社會의 經濟去來가 約款에 의한 大量·集團契約에 주로 의존하게 되면서 約款은 國民經濟 전체에 영향을 미치는 社會問題로 대두되었고, 이의 적절한 規制가 法學者 및 法院에 의해 널리 지적되기에 이르렀다. 우리 나라에 있어서 約款에 대한 一般의 認識이 높아지게 된 때는 70년대 이후 經濟成長이 高度化되면서 부터이며 獨逸의 約款法이 制定된 후 그 關心이 급격히 고조되었다. 政府의 關聯機關과 法曹界, 學界는 물론 一般 消費者들 사이에서도 約款에 대한 認護이 새로워지기 시작했으며, 約款에 대한 활발한 관심과 硏究의 축적은 約款規制를 위한 立法으로 이어졌다. 그러나 約款規制法의 制定에도 불구하고 이를 직접 援用하는 大法院判決이 이제서야 비로소 하나 둘씩 나오는 우리현실에서 約款規制와 消費者保護의 問題는 계속해서 關心을 가지고 살펴보아야 할 問題라고 할 수 있다. 특히 급속하게 변화 발전하는 현실 去來界에서 消費者들의 意識實態에 따른 效率的인 法制度 강구를 위한 노력이 필요하다고 생각한다. 이에 따라 本稿에서는 約款의 槪念과 本質, 解釋論에 의한 規制方法 등을 중심으로 한 기왕의 硏究成果들을 다시 한 번 간략하게 檢討·比較·整理하는 한편, 約款規制를 통해 消費者保護라는 소기의 목적을 보다 效率的으로 달성하기 위해 紛爭時 抽象的 審査를 擔當하는 公正去來委員會의 組織과 世界化의 趨勢에 맞춰 밀려오는 ‘경쟁라운드(CR)’등 對外協力分野의 補强과 旣存의 次官級 機關에서 長官級으로의 格上에 따른 公正委의 位相 確立을 위해서는 組織改編이 불가피하게 되었다. 현재 公正去來委員會의 部署中 가장 일손이 달리는 部署는 下都給課를 꼽을 수 있다. 大企業과 中小企業, 中小企業과 中小企業間의 下都給去來 紛爭을 다루는 下都給課는 현재(1996년 5월) 公正委에 밀려 있는 2백60여건의 사건 중 2백여건을 맡고 있을 정도로 業務가 폭주하고 있는 상황이다. 이와 함께 消費者保讓業務와 가장 밀접하게 관련되는 各種 約款審査業務도 일손이 모자라 人員補强이 必要한 狀況이다. 특히 現在 서울高法 判事가 法務擔當官으로 派遺 나와 指輝하고 있는 분야는 辯護士·法學敎授등 法曹 專門人力의 充員이 필요한 것으로 指摘되고 있다. 對外協力分野 역시 곧 다가올 경쟁라운드(CR)를 감안할 때 補强이 時急한 分野로 指摘되고 있다. 以上과 같은 問題點을 解決하기 위해서는 △約款·表示廣告局 △國際業務局 등 2개 實務局을 新設하여야 하고, 公正去來業務와 직결돼 있는 消費者保護 行政을 效率的으로 펴기 위해 財政經濟院의 消費者保護業務를 넘겨 받아야 할 것이다. 다시 한번 부연하지만 約款規制와 消費者保護를 위한 合理的 方法은 먼저 消費者에 대한 情報提供 및 弘報 强化와 消費者保護機橫의 擴大改編이 先行되어야 한다. 消費者保護廳을 新設하고 特別한 保護領域에 대한 專門的機關(예컨대 約款審査委員會 등)의 權限을 신장시키는 한편 規制基準과 不當約款의 內容 등이 여타 企業 및 消費者들에게 影響力있게 受容·홍보될 수 있도록 하고, 나아가 이들 專門機關과 地方自治團體, 民間消費者團體 등과의 協助 및 連繫를 보다 긴밀히 함으로써 消費者被害를 豫防的으로 防止하는데 주력하여야 한다. 그리고 대부분이 少額·多數인 約款訴訟의 特殊性을 勘案하여, 訴訟상 節次를 迅速하게 處理할 수 있도록 全擔裁判部를 設置하는 方法을 고려한다. 그리고 旣判力의 제3자에 대한 效力을 例外的으로 擴張시킬 수 있는 方案을 강구하거나 그 要件이 보다 緩和된 形態로 團體(集團)訴訟을 可能하게 함으로써 消費者被害의 事後的 救濟가 消費者들에게 손쉽게 利用될 수 있도록 하여야 할 것이다. As our society is rapidly industrialized and developed the mass production, the contract is almost made by standard-form contracts. Especially this type of contracts are used by the enterprises with strong economic power. Standard-form contracts are entered into only by the standard clause in modern enterprises which consumers are beyond the stretch of expectation. Once this contract is made by the enterprises are used in every bargain dealing with the same product or service, are not in a position to strike a bargains for clauses. So, we should have a great concern for the abuse of the standard-form contract as their use spread into almost all fields of enterprises. The purpose of this thesis is not study the theories and the substance of the standard-form contracts, it's interpreting method and the regulating system by Government. Why the consumers should by the standard-form contracts? how are they formed. Here the problems arise. Should the consumers be subdue with the one-sided contract condition the enterprises produce? There is an opinion that the lawful essence of the standard-form contracts is a kind of regulation. But I think that this opinion could' t explain the essence of standard-form contracts to the full. I insist, before the contract is entered into, the standard-form contracts is merely a model of contract. The contract is made by the standard-form contracts should be all the way understand at the level of contract-law. Furthermore, it should be considered that the contract made by standard-form contracts has a characteristics of contract-law, but I conceived that there are some exceptions. Usually, this type of contracts are used by enterprises with strong economic power and there are many one-sided clauses. Thus it is necessary to restrict them in contents. In particular, all the principles of interpreting the standard-form contract letters that have ever been done are inadequate. So, the ground that one party to the contract is bound with the standard-form contracts is based on the objective agreement between two contracts and also this should be examined not as the problem of between two individual contractors but as the problem of between two individual contracts but as the problem of type of the class to which the consumers belongs. As to conditions based on the requirement of capital supporting the institution, the principle of the liberty of contract and the principle of sincerity, it can be inferred that the contractors objectively agrees to the conditions. Therefore we may regard that the contractors objectively agrees to the several conditions based on the technical frame of the transaction institution out of all formal contract clause of the standard-form contracts of enterprises. In form, the objective intention is the general one which exist for all contractors in the class to which the consumers belongs using the general conditions concerned. The objective agrees in here, is the confirmation of the objective agreement in th party to the contract deserved above should be done in the transaction of the consumers and not be needed in the transaction among enterprises. I think that the basic defects of the clause and conditions of the standard-form contracts is on the standard-form contracts itself. So, when we restrict the content's of contracts, we determined the limits of the clause and conditions of the standard-form contracts. In this, we have to exams whether the bargaining power maintains a balance and whether the contract can be well negotiate with each other. Thus, with the need of objective agreement, above two things are important to decide the limits of the standard-form contracts' contents. Because it is necessary that the contents of standard-form contracts is to the effective at the guess of the intentions of the contractors. The last, viewing from the standpoint of the law-policy, I tried to research the method of the control over the unjust standard-form contracts by government. Generally three kinds of method known to us that controled through Judical, administrative and legislative measures. But to find any of them insufficient. The Judical control, which is done after something undue has happen, is not practical measure. The administrative control also have some defects. I think, from the standpoint of the law-awareness of our society, the better measure is legislative control that can make any necessary measure becomes laws to regulate the unjust clauses and conditions of contracts. Nowadays, it is impossible not to accept the existence of standard-form contracts admitting that there exist some unjust and undue clause and conditions. So, The Government should be concerned in the standard-form contract to protect the consumers whom the economic weaker party. The contents of this thesis are as follows. Chapter I . Introduction The introduction was prescribed the objects, ranges and methods of this study. Chapter II. The concept of the standard-form contract and function. Chapter III. The Restriction of standard-form contract. Chapter IV. The fair trade commissions construction reorganization of aplan Chapter V. A consumers protection a method and policy presentation of concrete Chapter VI. Conclusion

      • 단백질과 다당류 혼합물을 첨가한 냉동반죽의 제빵특성

        정정일 전남대학교 대학원 2003 국내석사

        RANK : 1855

        냉동반죽에서 이스트 활동의 저하로 인한 동결 장해와 반죽의 동결 손상으로 제빵성이 저하되는 것을 막기 위한 방법의 하나로 단백질-다당류 혼합물(1:1)을 냉동반죽에 첨가하여 빵을 제조한 후 제빵에 미치는 영향을 조사하였다. 냉동반죽 제조 시 사용된 단백질-다당류 혼합물은 CA(casein-sodium alginate mixture), CC(casein-κ-carrageenan mixture), WA(whey-sodium alginate mixture), WC(whey-κ-carrageenan mixture)로서 밀가루의 1.6%로 첨가하여 각각 반죽을 제조한 후 -40℃에서 3시간 냉동하고 -20℃에 보관하면서 실험에 사용하였다. Farinograph와 amylograph를 이용하여 단백질과 다당류 각각을 혼합한 제빵용 밀가루의 반죽특성을 조사하였고, 빵의 비용적, 수분함량, 텍스쳐, 색도, 관능검사를 실시하여 혼합물을 첨가하지 않은 대조구와 비교 조사하였다. Farinograph에 의하면 sodium alginate와 κ-carrageenan 첨가구의 수분 흡수력이 65,7%에서 68.0%과 69.5%로 증가하였고 casein과 whey protein 첨가구는 65.7%와 65.1%로 같거나 비슷하였다. Stability는 sodium alginate 첨가구가 21.3분으로 첨가구 중 가장 컸지만 대조구의 23.0분보다 낮았으며 반죽 형성시간은 sodium alginate 첨가구가 12.2분으로 대조구 4.0분의 3배 정도로 증가하였고 그 외의 첨 가구에서는 2.2∼4.5분으로 조금 감소하였다. V/V(valorimeter value)는 sodium alginate 첨가구가 88로 대조구 67보다 높았지만 다른 첨가구에서는 44∼66으로 대조구보다 낮았다. Amylograph에 의한 호화개시 온도와 최고점도 온도는 sodium alginate, κ-carrageenan, casein 첨가구 각각이 대조구 62.5℃와 90.8℃보다 높았고 최고점도는 대조구 720 B.U보다 낮았다. 비용적에 있어서는 CA, 대조구, CC, WA, WC 첨가구의 순으로 높게 나왔고 CA 첨가구의 경우 총부피와 비용적에 있어 가장 우수하였다. 저장중의 수분함량은 대조 식빵보다 단백질-다당류 혼합물 첨가 식빵이 높은 경향을 보였다. 텍스쳐에 있어서 견고성은 저장에 따라 모두 증가하였지만 CA, CC, WA 첨가구의 경우는 대조구보다 증가율이 작았고 WC 첨가구의 경우는 비슷하였다. 탄력성은 첨가 식빵에서 감소하였고 응집성은 대조 식빵과 비슷하였고 씹힘성은 감소하는 경향을 보였다. 색도에 있어서는 L(명도)값은 대조 식빵보다 높게 나왔고 a(적색도)값은 감소하였으며 b(황색도)값은 조금 낮은 경향이었다. 그리고 관능검사에 있어서 첨가 식빵과 대조 식빵 모두 3점 이상을 받아 전체적인 기호도에 있어서 긍정적이었음을 알 수 있었다. 이를 종합해 볼 때 냉동반죽 제조 시 반죽에 CA와 WA를 첨가하면 동결손상으로 인한 제방성의 저하를 억제할 수 있으며 제품의 노화를 억제하는 것을 통해 제품의 저장 수명을 연장시킬 수 있을 것으로 생각되어지며, sodium alginate 첨가로 인한 비만방지와 콜레스테롤 저하에 대한 기능성 효과는 소비자들에게 긍정적인 인자로서의 상승효과가 크게 작용하리라고 본다. In order to prevent lowering quality of bread because of the decrease of yeast activity and the damage to the gluten network due to freezing, this study was undertaken to examine the effect of addition of protein-polysaccharide mixtures in the frozen dough. Protein-polysaccharide mixtures was consest of CA(casein-sodium alginate mixture), CC(casein-κ-carrageenan mixture), WA(whey-sodium alginate mixture), WC(whey-κ-carrageenan mixture), which is added with 1.6% of wheat flour. Each dough was used to investigate after frowning at -40℃ for 3 hours, and then preserving at -20℃. It is investigated to see quality of dough made of wheat flour mixed each of protein and polysaccharide using Farinograph, Amylograph. After mading product, specific loaf volume, moisture contents, texture, color, sensory evaluation were undertaken to compare it with control not added mixture. Seen by farinograph, in water absorption sodium alginate and κ-carrageenan were increased from 65.7% to 68.0% and 69.5%, casein was to 65.7%, whey protein to 65.1% which was the same or alike. In stability, sodium alginate was the longest of wheat flour containing each of protein and polysaccharide which is 21.3 minute. But control was 23.0 minute. In dough development time, sodium alginate is 12.2 minute three times longer than control which is 4.0 minute. In extra wheat flour containing each of protein and polysaccharide, it was 2.2∼4.5 minute which was shorter. In V/V(valorimeter value), sodium alginate was 88 which was higher than control, in extra wheat flour containing each of protein and polysaccharide, it was 44∼66 which is lower than control. In gelatinezation temperature and temperature at maximum viscosity by amylograph, sodium alginate, κ-carrageenan, casein is higer than control, in maximum viscosity, it is lower than control. In specific loaf volume, CA was the best, followed by control, CC, WA, WC. In the moisture contents during the storage of bread, added bread and not added bread was changed slightly, so it was seen to have water holding capacity. In texture, hardness was increased with the time of storage, CA, CC, WA was increased a little, WC was alike. In springness and chewiness, added bread was decreased. In cohesiveness, added bread was alike to non added bread. In color, L(lightness) values was higher than that of non added bread. a(redness) values and b(yellowness) values were lower than that. And sensory evaluation showed that added bread and non added bread were all 3 points. So it was seen that general taste was positive. Finally, frozen dough added to CA and WA was prevented lowering quality of bread and preventing staling made shelf-life prolong. It is expected that the functional effects on inhibiting obesity and lowering cholesterol caused by adding sodium alginate will bring a lot of synergy effect as a positive element to customers.

      • Studies on the effect of peptide promoting osteoblast differentiation and small molecules showing anti-cancer activity

        정정일 Graduate School, Eulji University 2019 국내석사

        RANK : 1855

        Vitamin C-linker conjugated Ala-His-Lys tripeptide (Vit C-AHK) is a derivative of Vitamin C-conjugated tripeptides which was originally synthesized as a component of the product for hair growth enhancement or hair loss prevention. Here, I investigated the effect of Vit C-AHK on bone morphogenetic protein (BMP)-2 induced osteoblast differentiation in a cell culture model. Vit C-AHK enhanced the proliferation of C2C12 cells and induction of BMP-2-induced alkaline phosphatase (ALP), a typical marker of osteoblast differentiation. Vit C-AHK also stimulated the phosphorylation and translocation of Smad1/5/8 to the nucleus and phosphorylation of mitogen-activated protein kinases (MAPKs) including ERK1/2 and p38. Vit C-AHK also enhanced the BMP-2-induced mRNA expression of osteoblast differentiation relating genes such as ALP, BMP-2, Osteocalcin (OCN), and Runx2. These results suggest that Vit C-AHK exerts enhancing effect on osteoblast proliferation and differentiation without significant cytotoxicity through the activation of Smad1/5/8 and MAPK ERK1/2 and p38 signaling. These results provide important data for the development of peptide-based bone regenerative agents and treatment of bone-related disorders. Human acute T-lymphocytic leukemia (T-ALL) is one of the most commonly diagnosed hematological disorders, and is characterized by poor prognosis and survival rate. Despite the development of new therapeutic approaches, leukemia treatment options remain limited. In this study, I investigated the immunosuppressive and anti-proliferative effects of the synthetic estrogen diethylstilbestrol (DES), both alone and combined with the casein kinase 2 (CK2) inhibitor CX-4945. These results indicated that DES induced caspase-dependent apoptosis in a human T-ALL cell line (Jurkat cells), while exerting no significant cytotoxicity in normal peripheral blood mononuclear cells (PBMCs). Phytohaemagglutinin and phorbol 12-myristate 13-acetate induced interleukin (IL)-2 production and activation of NF-κB signaling pathways, which were both inhibited by DES. Moreover, DES exerted synergistic effects with CX-4945 on proliferation and IL-2 production in Jurkat cells. These results demonstrated that DES exerts anti-proliferative and immunosuppressive effects through inhibition of CK2 and the NF-κB signaling pathway in human T-ALL Jurkat cells. Brucea javanica (L.) Merr. is a medicinal herb that exhibits diverse biological activities against many types of human cells. In this study, I evaluated the anti-proliferative and anti-inflammatory effects of Brucea javanica (BJ) extract in a human T-ALL Jurkat cell line. These results showed that BJ extract induced caspase-dependent apoptosis of T-ALL Jurkat cells through inhibition of the CK2-mediated signaling pathway, while exerting no significant cytotoxicity in normal peripheral blood mononuclear cells. Moreover, BJ extract suppressed the NF-κB signaling pathway, thus inhibiting the interleukin (IL)-2 expression induced by phorbol 12-myristate 13-acetate (PMA) and phytohemagglutinin (PHA). Notably, combined treatment with BJ extract plus CX-4945 or imatinib exerted synergistic inhibitory effects on T-ALL cell growth and IL-2 production. Overall, these results suggest that BJ extract can be a potent therapeutic herbal agent for T-ALL treatment and prevention of IL-2 mediated inflammatory immune responses.

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