우리나라 土地 및 住宅政策의 問題點과 改善方案에 관한 硏究

반영해 대구대학교 2002 국내석사

We have witnessed various real estate problems, while we have been developing our national land and constructing cities. The examples were high land price, economic problems accompanied, housing shortage, pollution and other environmental issues. In order to solve such problems, the government has enacted and implemented various codes and succeeded in solving some of them, but could not solve them spmplete1y due to the difficulty inherent in them. For example, the price of real estate cannot be entirely dictated by the principle on economy. Real estate is essential for human life, and therefore, it is necessary to compare, review and study the various real estate policies and thereupon, explore more effective ways to use them. With such a basic conception in mind, this study was aimed at reviewing the land and housing policies. To this end, the following aspects of land and housing Policies. First, such issues involving land as unbalanced supply and demand of land, higher land price and resultant social problem, privatization of developed land profits and inequality, biased land ownership, insufficient land systems, etc, were comparatively evaluated in the light of land system and conventional land policies, and then, the effects of the information-intensive society on changes of social structure and land were illuminated in the lights of land policy directions, goals and strategies. Second, we have a land too narrow to accommodate the large population in terms of housing. So, a longer-term housing policy must be based on a smooth supply of housing sites. In some metropolitan areas, the land available has been almost exhausted, while the speculations in land have subsisted for unearned incomes. The result was distorted and unreasonable distribution of land among people. The recent housing and land policies can be appreciated as expanded the supply of land and housing sites and thereby, stabilized the land price, but they may well be problematic in view of efficient and equal land uses. In this study, redevelopment of poor houses, development of housing sites and activation of land receivership system are suggested as reform measures for real estate policy. Therefore, this study reviewed "the effects of real estate price on economy", and explored the ways to solve the various real estate problems from the political viewpoint and thereby, maximize the uses of land to the benefit of the nation's industrial development and people's living.

도시관광 마케팅 커뮤니케이션, 브랜드 인지도, 브랜드 이미지, 관계지속의도 연구

반영해 전주대학교 대학원 2020 국내석사

세계화 시대에 접어들면서 도시는 마케팅의 대상이 되었으며 관광의 대상으로서 많은 사람들이 방문하는 관광목적지가 되었고 도시관광은 지역발전을 위한 전략적인 수단으로 인식되었다. 따라서 본 연구에서는 도시관광의 마케팅 커뮤니케이션, 브랜드 인지도, 브랜드 이미지, 관계지속의도에 대한 영향관계를 밝힘으로써 요인간 영향관계에 대한 학술적인 시사점을 도출함은 물론 관광지로서 전주의 지속적인 성장을 위한 효율적이고 체계적인 개선안과 관광객 유치에 필요한 마케팅 커뮤니케이션 요인 도출 등 실무적 시사점 제시에 본 연구의 목적을 두고 있다. 연구목적 달성을 위하여 전라북도 전주시 관광지를 지역범위로 한정하였고 전주시 이외의 지역에 거주하며 전주시 관광지를 방문한 관광객을 대상으로 전주한옥마을에서 실증조사를 실시하였다. 조사기간은 2019년 9월 1일부터 9월 31일까지 진행하였으며 설문조사는 연구자 본인과 사전에 교육된 조사원에게 조사 목적 및 방법을 설명듣고 설문지를 바탕으로 자기기입식 조사방법으로 실시하였다. 설문지는 총 300부를 배포하여 불성실한 답변 등 분석에 부적합한 40부를 제외한 260부를 유의표본으로 하여 조사 분석의 대상으로 선정하였다. 수집된 자료의 통계적 처리는 데이터 코딩 작업을 거쳐 실증분석을 실시하였다. 자료에 대한 분석방법은 통계패키지 SPSS-WIN 20.0을 이용한 빈도분석, 신뢰도 분석, 요인분석, 회귀분석 등을 실시하였다. 분석결과 첫째, 마케팅 커뮤니케이션의 광고, 구전 요인이 브랜드 인지도의 브랜드 인지에 영향을 미치며, 브랜드 구별에는 광고, 홍보, 구전의 3가지 요인 모두 영향을 미치는 것으로 나타났다. 이는 광고, 홍보, 구전이 인지적 수준에서 전주시를 방문하는 관광객들에게 호소되어 전주를 관광지로 인지하고 다른 지역 관광지와 구별할 수 있는 등 브랜드 인지도를 형성하는데 관계있는 것으로 풀이된다. 특히 구전 마케팅이 가장 큰 영향을 미치는 것은 브랜드 인지도로 이에 대한 적극적, 효율적 활용이 필요하다. 둘째, 마케팅 커뮤니케이션의 광고, 홍보, 구전의 3가지 요인 전부 브랜드 이미지에 영향을 미치는 것으로 확인되었다. 이러한 결과는 브랜드 이미지를 호의적으로 형성하기 위해서는 광고, 홍보, 구전을 이용하여 커뮤니케이션에 자원투자와 메시지 형태를 전략적으로 고려해야 함을 시사해 준다. 셋째, 마케팅 커뮤니케이션의 광고, 홍보, 구전의 3가지 요인 모두 관계지속의도에 영향을 미치는 것으로 나타났다. 특히 브랜드 인지도, 브랜드 이미지와 마찬가지로 관계지속의도에 가장 큰 영향을 미치는 구전활동에 중점을 둘 필요성이 있다. 넷째, 브랜드 인지도의 브랜드 인지, 브랜드 구별 2가지 요인 전부 브랜드 이미지에 영향을 미치는 것으로 확인되었다. 브랜드 인지도는 브랜드 이미지 형성에 영향을 주는 요인임을 감안할 때, 꾸준한 관광지에 대한 광고, 홍보, 구전 관리를 통해 관광지에 대한 인지도 향상 및 이를 통한 긍정적인 브랜드를 형성하기 위한 전략을 수립할 필요가 있다. 다섯째, 브랜드 인지도의 브랜드 인지, 브랜드 구별 2가지 요인 모두 관계지속의도에 영향을 미치는 것으로 나타났다. 전주를 관광지로 인지하는 것은 관광을 위해 재방문하거나 자신의 경험이 긍정적 구전으로 이어지는 인과관계가 존재하기 때문에 인지도를 높이기 위해서는 다양한 인지도 속성들에 초점을 맞춘 마케팅 커뮤니케이션과 전주에 대한 효과적인 관광정보제공이 필요함을 의미한다. 여섯째, 브랜드 이미지가 관계지속의도에 영향을 미치는 것으로 나타났다. 전주의 아름다운 경관, 관광인프라, 친절성, 즐길거리, 매력성, 쾌적성, 편안함, 즐거움의 이미지 구축과 홍보를 통해 관광객이 전주를 재방문하고 긍정적 구전이 이뤄질 것으로 보인다. 본 연구는 연구목적 달성을 위해 여러가지 시사점을 도출하여 제시하고 있으나 연구대상의 한계, 마케팅 커뮤니케이션 요인의 선별적 연구, 조사지역의 한정 등의 한계점을 지니고 있다. 향후 연구대상 및 조사지역의 확대, 마케팅 커뮤니케이션 요인의 다양화, 온라인 사용자를 대상으로 하는 온라인 구전 등에 대한 실증 연구를 통해 더욱 다양한 시사점을 도출할 필요성이 있다. With the emergence of the globalization era, cities have become the subjects of marketing and tourist destinations that many people are visiting, with urban tourism being recognized as a strategic means of local development and growth. Therefore, this study is aimed at presenting practical implications by not only deducing academic implications on the influential relationships among the factors including marketing communication, level of brand awareness, brand image and intention to sustain relationship of urban tourism by also deducing proposal for efficient and systematic improvements necessary for sustained growth of and marketing communication factors necessary for enticing tourists to Jeonju as a tourist destination by disclosing the influential relationships among the aforementioned factors. For the accomplishment of the research goals of this study, the tourist destinations in Jeonju City, Jeollabuk-do were limited to the regional areas, and an empirical survey was conducted on the tourists residing outside Jeonju-si visiting the tourist destinations in Jeonju-si at the Jeonju Hanok(traditional Korea houses) Village. Survey was conducted from September 1 to 31, 2019 in the format of a self-administered questionnaire survey on the basis of the instructive words indicated in the questionnaire after having provided explanations on the purpose and method of the survey by the researcher and pre-trained survey administrators. A total of 300 questionnaires were distributed and 260 copies with the exclusion of 40 copies inappropriate for analysis due to reasons such as insincere answers were used as purposive samples and were selected as the subjects of survey analysis. Empirical analysis was executed on the data collected after having undergone data coding work for the statistical processing of the said data. Statistical analysis methods applied for the data collected included frequency analysis, reliability analysis, factor analysis and regression analysis, etc. by using the statistical package SPSS-WIN 20.0. The following results were obtained from the analysis. First, factors such as advertisement and word-of-mouth of marketing communication have effects on the brand recognition of the level of brand awareness, while all 3 factors, namely, advertisement, promotion and word-of-mouth, affect the brand distinction. This can be interpreted as advertisement, promotion and word-of-mouth are associated with establishment of brand awareness by appealing the tourists to Jeonju-si to recognize Jeonju as a tourist destination and to distinguish it from other regional tourist destinations at cognitive level. In particular, it was found that marketing through word-of-mouth has the greatest effect on the level of brand awareness, thereby needing efficient and assertive utilization thereof. Second, all 3 factors of marketing communication, namely, advertisement, promotion and word-of-mouth, were found to affect the brand image. This result imply that infusion of resources into and forms of message contents of communication utilizing advertisement, promotion and word-of-mouth must be considered strategically in order to establish favorable brand images. Third, all three factors of marketing communication, namely, advertisement, promotion and words of mouth, were found to affect the intention to sustain relationship. In particular, similar to the case of level of brand awareness and brand image, it is necessary to focus on the activities for word-of-mouth that impart the greatest effect on the intention to sustain relationship. Fourth, two factors of the level of brand awareness, namely, brand recognition and brand distinction, were found to affect the brand image. When considering the fact that level of brand awareness is a factor that affects establishment of brand image, there is a need to establish strategy for improvement of the level of awareness of the tourist destination through continuous management of advertisement, promotion and word-of-mouth for the tourist destination, and ensuing affirmative building up of brand. Firth, two factors of the level of brand awareness, namely, brand recognition and brand distinction, were found to affect the intention to sustain relationship. Since there is causal relationship between the recognition of Jeonju as a tourist destination and ensuing revisit for tourism or affirmative word-of-mouth on the visitor’s experience, it is necessary to execute marketing communication focused on the diversified attributes of the level of awareness to enhance it and to provide effective tourism information on Jeonju. Sixth, it was found that brand image affects the intention to sustain relationship. It appears that the establishment and promotion of the images of beautiful scenery, tourism infrastructure, kindness, things to enjoy, attractions, pleasantness, comfort and enjoyment of Jeonju will lead to revisiting of Jeonju and affirmative word-of-mouth by the tourists. Although this study deduced and presented diversified implications for the purpose of research, it has several limitations including the limitation in the study subjects, selective study of marketing communication factors and limitation of the survey area, etc. Therefore, there is a need to deduce more diversified implications through expansion of the research subjects and survey areas, diversification of marketing communication factors and empirical study on online word-of-mouth with online site users as the subjects, etc. in the future.

都市近隣公園의 適正立地 選定方法

반영운 (潘榮云) 延世大學校 大學院 1988 국내석사

Altered signal transduction pathway and protein localization during senescence maturation in HeLa cells

반영재 서울시립대학교 2004 국내박사

1인 가구의 미충족 의료 관련 요인 분석 : 국민건강영양조사 제 4기, 5기 조사(2007년-2012년)를 중심으로

반영각 연세대학교 보건대학원 2015 국내석사

1인 가구가 최근에 급속히 증가하고 있다. 또한 건강 증진에 대한 사회적 관심도 높아지고 있다. 혼자 사는 1인 가구는 질병 이환의 영향을 미치는 위험요인이다. 그러므로 1인 가구는 건강 증진 측면에서 고위험군이다. 우리나라는 저부담-저급여 건강보험정책과 낮은 보장성으로 필요한 의료 서비스를 이용하는데 한계가 있다. 이러한 보건의료의 형평성을 파악하기 위해서는 미충족 의료 경험에 주목해야 한다. 건강행동특성에 있어서 고위험군이 1인 가구의 미충족 의료 관련 요인을 분석함으로서 향후 1인 가구의 미충족 의료 경험을 줄이는 방안을 모색하거나 1인 가구의 건강관리에 대한 합리적인 보건의료정책을 마련하는데 기초자료를 제시하고자 한다. 본 연구는 제4기(2007-2009), 제5기(2010-2012) 국민건강영양조사 자료를 이용하였으며, 건강설문조사에 응하였던 만 19세 이상인 총 38,005명 중 가구원수가 1인이라고 답한 2,390명을 대상으로 분석하였다. 선행연구 고찰을 통해 1인 가구 미충족 의료 경험에 영향을 주는 요인들을 파악하여 변수를 설정하였다. 기술분석과 Survey특성을 고려한 Rao-scott chi-square 검정과 logistic regression을 시행하였다. 통계분석에는 SAS ver. 9.4를 사용하였다. 연구결과 2,390명의 1인 가구 중 최근 1년 동안 미충족 의료 경험이 있는 723명으로 전체 대상자의 28.3%였다. 미충족 의료 경험여부에 대한 인구사회적요인과 건강행태요인을 Rao-scott chi-square 검정을 통해 분석한 결과, 여성인 경우, 70세 이상인 경우, 결혼 경험이 있는 경우, 교육수준이 낮은 경우, 충청 · 전라/제주 · 경상지역인 경우, 저소득인 경우, 의료급여인 경우의 미충족 의료 경험률이 높았다. 그리고 비음주자, 비흡연자, 만성질환이 있는 자, 주관적 건강인식이 나쁘다고 생각하는 경우, 스트레스가 많은 경우, 우울한 경우, 자살생각을 한 경우 미충족 의료 경험률이 높았다. Survey특성을 고려한 logistic regression 결과, 결혼 상태에서 미혼인 경우보다 사별한 경우 미충족 의료 경험률 교차비가 0.49였다. 균등화 월가구소득에서 30만원 이하 소득에 비해 50-100만원 소득군의 미충족 의료 경험률 교차비가 0.64였다. 주관적 건강인식이 좋은 군에 비해 나쁜 군의 교차비는 1.91이었다. 스트레스에서는 ‘거의 느끼지 않음 군’에 비해 ‘많이 느낌’, ‘대단히 많이 느낌’의 교차비는 1.82, 1.99이었다. 2주 이상 연속 우울감은 없는 경우에 비해 있는 경우의 교차비는 1.44이었다. 1년간 자살생각은 없는 경우에 비해 있는 경우의 교차비는 1.77이었다. 이 연구는 1인 가구만을 대상으로 인구사회적요인과 건강행태요인을 광범위하게 보정하여 분석한 연구이다. 특히, 만 19세 이상의 1인 가구의 미충족 의료 현황을 포함하였고, 최근 6개년도 국민건강영양조사 자료를 통합하여 분석을 시도하였다. 이를 통해 1인 가구의 미충족의료 관련 요인이 인구사회적 요인보다는 주관적 건강인식, 스트레스, 우울, 자살생각의 건강행태변수 중 정신건강요인이 미충족 의료에 관련이 있는 것으로 밝혀졌다. 연구결과를 토대로 볼 때, 기존 연구에서 도출된 미혼, 저학력, 저소득층 미충족 의료에 대한 대책뿐만 아니라, 인구사회적요인 보다 건강행태요인 중 특히, 1인 가구의 기존연구에서 언급된 정신건강 요인인 주관적 건강인식, 스트레스, 우울감, 자살생각 요인에 대한 대책을 정책에 반영하여 설계할 필요가 있다. The number of single-person households has increased drastically over the last few years. The social interests for the health promotion is increasing. Single-person households can be one of risk factors which influence a morbidity. In terms of that, single-person households will be ranked as a high-risk group. The public health insurance of South Korea has the low coverage of the low burden and low payment policy. Therefore, it is a barrier to use the necessary healthcare services. To understand the fairness of health care service, the unmet health care experience must be noticeable. We have analyzed that the factors of the unmet health care related with the health behavior factors for the single-person households. In this study, we suggested the ways to reduce the unmet healthcare experience of single-person households for the future, and we presented the basic data to provide a reasonable health care policy for the single-person households on the health management. Forth (2007-2009) and 5th (2010-2012) National Health and Nutrition Examination Survey (KNHANES) were used. Two thousand three hundred and ninety single-person households out of the total 38,005 people who are aged more than a full 19-year-old were subjected. Through the discussion of previous studies, we set the variables to understand the factors that affect single-households unmet medical experience. The technical analysis, the Rao-scott chi-square considering Survey characteristics, and logistic regression were underwent. For the statistical analysis, SAS version 9.4 was used. Results, Six hundred fifty-six people who had the unmet medical experience are 28.3% among 2,390 single-person households. The social factors and the health behavior about the unmet medical experience were analyzed using Rao-scott chi-square test. The people who are women, have a marriage experience, live in Chungcheong, Jeolla and Jeju, have low education level, have low income, receiving a medicaid showed the higher unmet medical experience rate. The people who are non-drinker, non-smoker, have a chronic disease, have low cognizance of their health awareness, with high stress, with depression, ever had suicidal ideation showed the higher unmet medical experience rate. The logistic regression considering the survey characteristics resulted that the odds ratio of the unmet medical experience rate of the unmarried women-group was 0.49 compared to the widows-group. The odds ratio of the unmet medical experience rate of the 500,000 to 1000,000-won income group was 0.64 compared to 300,000-won or less income group in the equalize monthly income. The odd ratio comparing the group of high cognizance of subjective health awareness with the group of low was 1.91. In the stress, the odds ratio comparing ‘feeling not much’-group compared to the ‘feeling a lot’-group and ‘feeling much’-group were 1.82, 1.99. The odds ratio comparing ‘continuous depression more than two weeks’-group to ‘non-continuous depression more than two weeks’ was 1.44. In the case of comparisons of ‘one-year suicidal ideation’-group and ‘non-suicidal ideation’-group, the odds ratio was 1.77. The single-person households were only subjected to this study. The socio-demographic factors and the health behaviors factors were adjusted and analyzed in several ways. Especially, It includes the unmet medical situations of over 19 years-old single-person households. We analyzed the KNHANES combined data of the last six-years. As a result, it shows that the health behavior factors, stress, depression, and the suicidal ideation are related to the unmet health care rather than socio-demographic factors. Based on the results of this study, it is necessary to take measures to the unmet medical for the people with never married, low education and low income, which is derived in the existing research. In addition, psychological factors among other factors of health behavior than the socio-demographic, such as subjective health consciousness, stress, depression, suicidal ideation, should be consider with top priority.

상위인지 전략을 활용한 한국어 듣기 교수·학습 방안 연구 : 중국인 중급 학습자 대상으로

반영 전북대학교 일반대학원 2020 국내석사

In order to improve the listening comprehension ability of Korean learners, this study is aimed at intermediate level Chinese learners of Korean language and aims at proposing effective methods for learners to learn on their own. In this study, a Korean listening education plan using metacognitive strategy that can be applied to practical education is formulated. It is hoped that this program can help Chinese teachers better guide the Korean listening of students in the field of actual education. The first chapter, as an introduction, clarifies the necessity and purpose of this study, and reviews relevant previous studies. The second chapter is mainly to lay the theoretical foundation of the proposed listening teaching program and to analyze the previous researches on relevant listening and metacognitive strategies. In the third chapter, in order to understand the current situation of listening education in China and prove the necessity of using metacognitive strategy in listening courses, a questionnaire survey was conducted to Korean language teachers and intermediate level Korean language learners. Through the research, it is found that to improve the teaching effect of Korean listening, it is necessary to use metacognitive strategy to teach in the way of learners' independent learning. In order to effectively realize such a listening course, learners should take an active attitude to participate in learning and need to have the ability to learn independently. Teachers need to guide students to recognize the process of listening learning and help students to learn listening independently. In this regard, chapter 4, as the core part of this study, puts forward a specific teaching plan to improve Korean listening by using metacognitive strategy. In order to develop an effective teaching plan, this paper firstly discusses the principles of applying metacognitive strategy to guide listening comprehension in the field of education and the materials suitable for applying metacognitive strategy in listening comprehension curriculum. At the same time, through the analysis of the teaching elements, the teaching activities of Korean listening course which can be applied to the actual teaching scene are developed. Chapter 5 is both the conclusion and the direction of development. Here is simply sorted out all the contents of this study, and clarifies the significance and shortcomings of this study, as well as the need for further research.

관광지 음식정보품질이 관광지 음식이미지와 음식관광 참여의도에 미치는 영향

반영 경희대학교 일반대학원 2015 국내석사

본 연구는 인천 공항 out-bound 출국예정자 200명의 설문을 갖고 정보의 품질은 관광지 음식 이미지, 그리고 음식관광 참여의도에 영향을 미치며 이에 푸드네오포비아, 관광지의 방문경험 유무에 따라 유의한 차이가 있는지를 분석을 하였다. 실증 연구를 수행을 통해 총 4의 가설을 검증한 결과, 관광지 음식정보의 품질은 관광지음식 이미지에 영향을 미치며 음식관광 참여의도에 영향을 미치는 것으로 나타난다. 관광지 음식이미지의 형성에 음식정보품질의 중요성을 제시하여 긍정성의 역할을 확보하였다. 그리고 푸드네오포비아와 경험 유무에 따라 이미지 형성 시 정보품질 특성의 의존도가 다르다는 결과도 제시를 하였다. 음식이미지는 음식관광의 참여의도에 영향을 미치는 것을 검증이 되었다. 향후 연구는 in-bound대상도 확보하여 추가 연구할 필요성이 있다. This study explored to identify the food information quality, and the effects of the food information quality tourist destination on food image and tourism participation intentions. A factor analysis and a reliability test was conducted to a total of 300 copies from the internet survey using SPSS 21.0. The proposed research hypotheses were verified through a multiple regression analysis. The results of hypothesis verification are as follows. First, tourist destination food information`s quality which tourist owned have a partially significant impact on tourist destination food image. Particularly, food neophobia and previous experience influences the relation between the information quality and the tourist destination food image. Second, Second, the food image have a positive significant impact on Food Tourism Participation Intentions. The result of this study will be helpful with tourist industry which needs to develop culinary and food-related experience tour program.

중학교 씨름선수들의 지각된 내적 동기 성향 분석

반영중 청주대학교 교육대학원 2004 국내석사

The analysis was made on the survey of male middle school Ssi-reum(Korean wrestling) players at the age of 14 to 16 categorized into grades(first/ second/third year) and weight. And the results are as follows: First, there showed significant difference in the level of efforts and importance according to school years and weight of the students but no iteractions among those in different grades and weight. Second, there appeared significant difference in the level of tensions and anxiety according to weight of the students but no interactions among those in different grades as well as between different grades and weight. Third, there showed significant difference in the level of efforts and importance according to school years and weight but no interactions among those in different grades and weight. Fourth, there appeared significant difference in the level of tensions and anxiety according to weight but no interactions among those in different grades as well as between different grades and weight. Fifth, there showed the competent effect between different grades and weight but no difference according to grades and weight. Sixth, there existed interactions of interest and excitement across all the grades and weight. Last, there showed significant difference in the students' motivations for Ssi-rum according to their grades and weight by examining the overall motivations behind them. In conclusion, the assumption ⅰ), ⅱ), and ⅲ), which was prepared for analyzing the motivations of school Ssi-reum players according to their interactions across all the grades and weight, were partially adopted to explain many of their motivations. Therefore, it is safe to say that the Ssi-reum players' motivations for the game are varied by their interactions across all the grades and weight.

개 후각망울에서 칼슘결합단백질인 Parvalbumin과 Calbindin D-28K 면역양성반응 신경세포에 관한 연구

반영수 조선대학교 대학원 1999 국내박사

We have studied the distribution of calcium-binding proteins parvalbumin(PV) and calbindin D-28kCB) immunoacitivity in the mongrel dog olfactory bulb using monoclonal antibodies and the avidin-biotin-immunoperoxidase method. The possible coexistence of both markers was determined by segmental histochemical and immuohistochemical double labelling of the same section. In the olfactory bulb of mongrel dog, PV-IR and CB-IR were mainly located in the external plexiform layer, and a few scattered in the glomerular layer, mitral cell layer, and glanule cell layer in the order of their existence. In addition, three neuronal types were observed in the glomerular layer and external plexiform layer border. Horizontal cells and vertical cells of Cajal were also observed after both PV-IR and CB-IR labeling. Distict groups of PV-IR and CB-IR, differing in size, shape, dendritic branching pattern, and staining intensity, were distinguished in the all layers of the olfactory bulb. Specific neuronal populations were positive for both PV-IR and CB-IR markes. No cell colocarized both stains in the mongrel dog olfactory bulb. The number of PV-IR were more than abundent in olfactory bulb compared to the CB-IR cells. The PV-IR and CB-IR positive, cell somata were round, oval, spindle and polygonal in shape, and the positive neurons were unipolar, bipolar, multipolar and horizontal in shape. The diameters of the somata of the two positive neurons were 20-40㎛, respectively. Also dendrites of two positive neurons were densely arrayed in arborization.

항콜린제 투여 중단후 약물 유발 추체외로 증상의 변화에 미치는 요인에 관한 연구

반영진 翰林大學校 1990 국내석사

There are much controversy on the necessity of combined maintenance antiparkinsonian medication in chronic schizophrenic patients. But systematic study about factors influencing extrapyramidal side effects (EPS) after discontinuation of antiparkinsonian medication is lacking. This study was done to elucidate especially the influence of haloperidol blood level and anticholinergic side effects on EPS after anticholinergics discontinuation. In 23 chronic schizophrenic male patients the severities of EPS and anticholinergic side effects(ACS) were assessed each using modified Chien's EPS scale and authors' ACS scale, before and 10 days after discontinuation of benztropine. Blood sampling for haloperidol level was done once before anticholinergics discontinuation. The results are as follows: 1. Haloperidol blood level and various factors including age, duration of illness, duration of hospitalization, dosage and duration of benztropine treatment, chlorpromazine equivalent dose and its maintenance duration of used antipsychotics did not influence the change in severity of EPS after benztropine discontinuation. 2. Subjects who had more ACS showed less EPS aggravation. 3. High potency antipsychotics alone users showed more EPS aggravation than low potency alone or combined users. 4. Changes in severities of EPS and ACS have no correlation each other. Above findings suggest the predictive value of ACS and antipsychotic drug potency in the aggravation of EPS after benztropine discontinuation.