서해안 양식패류 및 수환경에서 분리한 세균의 항생제 내성에 관한 연구

다국어 초록 (Multilingual Abstract)

This study investigated the antimicrobial resistance characteristics of bacteria isolated from cultured bivalves (Oyster and Manila clam) and aquatic environments(inland pollution sources and seawater) of the west coast of Korea. The sampling sites were Jawol-myeon (Ongjin-gun, Incheon) and Iwon-myeon (Taean-gun, Chungcheongnam-do).Samples of 30 cultured bivalves (Oyster 20 samples, Manila clam 10 samples) andsamples of 45 aquatic environments (inland pollution sources 20 samples, seawater 25 samples) were collected. A total of 1,077 strains, Enterobacteriaceae (419 strains), non-enteric Gram-negative bacteria (105 strains), Enterococcus spp. (85 strains) and Vibrio spp. (468 strains) were isolated and analyzed for antimicrobial resistance using minimum inhibitory concentrations (MICs). Enterobacteriaceaeshowed high resistance to ampicillin and the most diverse multiple antimicrobial resistance patterns among the 4 types of bacteria. Enterococcus spp. were highly resistant to daptomycin, and multiple antimicrobial resistance rate of 5.0% was shown only in inland pollution sources samples. Vibrio spp. showed high overall resistance to ampicillin and colistin, and showed a relatively low resistance rate compared to land-derived bacteria. However, in the sample of inland pollution sources, the multiple antimicrobial resistance was exceptionally 35.1%. The results of this study showed that the antimicrobial resistance and multiple antimicrobial resistance rates of bacteria isolated from inland pollution sources were higher than those in shellfish and seawater samples. Thus, the continuous inflow of inland pollutants should be properly monitored.