췌장의 혼합 관-내분비 암종 -1예 보고- = Mixed Ductal-Endocrine Carcinoma of the Pancreas -A Case Report-

다국어 초록 (Multilingual Abstract)

Mixed ductal-endocrine carcinoma of the pancreas is composed of ductal and endocrine carcinoma components and each component makes up a significant proportion in the primary tumor as well as in the tumor of metastatic sites. Mixed ductal-endocrine pancreatic carcinoma is exceptionally rare and, to our knowledge, only five cases have been reported in the literature. Recently we experienced a case of mixed ductal-endocrine pancreatic carcinoma with regional lymph node and hepatic metastases in a 63-year-old woman. Here, we report a case of mixed ductal-endocrine pancreatic carcinoma with a review of the literature.

참고문헌 (Reference)

1 "carcinoma of the pancreas associated with watery diarrheaand hypokalemia syndrome" 1458-62,

2 "Tumors of the pancreas .Atlas ofTumor Pathology. 3rd Series,Fascicle 20." ArmedForces Institute of Pathology 93-98, 1997

3 "Pancreatic carcinoma with duct" 1766-70,

4 "Pancreatic PP cell distributionand hyperplasia: immunohistochemical morphology innormal pancreas, chronic pancreatitis and pancreatic carcinoma." 319-31,

5 "Ontogeny,differentiation andgrowth of the endocrine pancreas." 436 : 527-538, 2000

6 "Mixedductal-endocrine carcinoma of the pancreas presenting as gastrinomawith Zollinger-Ellison syndrome an autopsy case with a 24-yearsurvival period." 435 : 606-611, 1999

7 "Mixed exocrine-endocrine tumors of the pancreas." 17 : 104-108, 2000

8 "Mixed ductal-pancreatic polypeptide-cell carcinoma of the pancreas." 41 : 122-126, 2002

9 "Mixed ductal-endocrine carcinoma of the pancreas A case studywith mixed ductal-endocrine metastasis double labelled for cytokeratinand synaptophysin" 124 : 284-286, 2000

10 "Mixed duct-acinar-isletcell tumor of the pancreas: report of a case," 31 : 177-179, 2001

11 "Malignant mixed exocrine-endocrine tumor of the pancreaswith unusual intracytoplasmic inclusions" 483-93, ultrastructpathol1993;17

12 "Immunohistochemicalstudy of endocrine cells in ductal adenocarcinomasof the pancreas." 441 : 249-255, 2002

13 "Immunohistochemicalcharacterization of an amphicrine mucinous islet-cell carcinomaof the pancreas" Gullichsen R 335-40, apmis1992;100

14 "Endocrine-paracrine cells in pancreatic exocrine carcinomas" 599-613, histopathology1981;5

15 "Ductuloinsular tumors of the pancreas.A light,electronmicroscopic and immunohistochemical study." 908-15,

16 "Ductal cancers of the pancreasfrequently express markers of gastrointestinal epithelial cells" 1655-65, gastroenterology1990;98

17 "Ductal adenocarcinoma of the pancreas Pathology and genetics of tumours of the digestive system WHO classification of tumours." IARC Press 221-230, 2000

18 "Argyrophilic and hormoneimmunoreactive cells in normal and hyperplastic pancreatic ductsand exocrine pancreatic carcinoma" 399-405,