The copper and zinc concentrations were measured in sera of 27 cases of hepatoma, 20 cases of stomach ca., 7 cases of esophageal ca., 12 cases of colorectal ca., 9 cases of lung ca., 18 cases of ovarian ca. and 48 cases of normal control in Chosun Uni...
The copper and zinc concentrations were measured in sera of 27 cases of hepatoma, 20 cases of stomach ca., 7 cases of esophageal ca., 12 cases of colorectal ca., 9 cases of lung ca., 18 cases of ovarian ca. and 48 cases of normal control in Chosun University Hospital from Jan. 1986 to July 1986.
The results are as follows;
1. The mean concentration of copper in serum of normal control group was 96.0±5.02㎍/㎗ (Mean±2SE), in hepatoma, stomach ca., esophageal ca., colorectal ca., lung ca. and ovarian ca. concentrations were significantly increased each 126.4+12.77, 125.6±11.29, 140.5±14.23, 117.3±11.91, 181.4±30.56 and 130.5±13.80㎍/㎗ (P < 0. 001) in comparison with the mean value of normal control group.
2. The mean concentration of zinc in serum of normal control group was 104.8±3.40㎍/㎗ (Mean±2SE), in hepatoma and lung ca. concentrations were significantly decreased each 65.1±7.27 and 72.7±12.86 ㎍/㎗ (P < 0. 00l).
3. The ratio of serum copper level to zinc level (Cu/Zn ratio) in serum of normal control group was 0.94±0.057 in hepatoma, stomach ca., esophageal ca., lung ca. and ovarian ca. concentration ratios were significantly increased each 2.09±0.324, 1.86±0.122, 1.50±0.114, 2.55±0.513 and 1.51±0. 243 (P < 0.001).