The Prognostic Implication of Metabolic Syndrome in Patients with Heart Failure

다국어 초록 (Multilingual Abstract)

Background and Objectives: Metabolic syndrome (MetS) increases the risk of heart failure (HF). The purpose of this study was to identi-fy the prevalence of MetS in patients with HF and determine the syndrome’s association with HF in clinical and laboratory parameters.
Subjects and Methods: A total of 3200 HF patients (67.6±14.5 years) enrolled in a nationwide prospective Korea HF Registry between Jan. 2005 and Oct. 2009. Patients were divided into two groups according to the presence or absence of MetS at admission: group I (pres-ence, n=1141) and group II (absence, n=2059).
Results: The prevalence of MetS was 35.7% across all subjects and was higher in females (56.0%). The levels of white blood cells, platelets,creatinine, glucose, and cholesterol were significantly higher in group I than in group II. Left ventricular dimension and volume was smaller and ejection fraction was higher in group I than in group II. An ischemic cause of HF was more frequent in group I. The rates of valvular and idiopathic cause were lower in group I than in group II. The rate of mortality was lower in group I than in group II (4.9% vs. 8.3%, p<0.001).
Conclusion: Despite the increased cardiovascular risks in MetS, MetS was found to be associated with decreased mortality in HF.

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