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ScienceONA new spiroketal, spirodienal B (1), was isolated from culture extracts of S. cellulosum. Its structure was elucidated by spectroscopic analysis. In addition to 1, the strain produced a second, closely related antibiotic, spirodienal. Both compounds d...
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RISS 인기검색어
https://www.riss.kr/link?id=A103882728
-
저자
곽종환 (성균관대학교) ; Jong-Woong Ahn (Korea Maritime University)
- 발행기관
- 학술지명
- 권호사항
-
발행연도
2009
-
작성언어
English
- 주제어
-
등재정보
KCI등재,SCIE,SCOPUS
-
자료형태
학술저널
- 발행기관 URL
-
수록면
841-844(4쪽)
-
KCI 피인용횟수
5
- 제공처
-
0
상세조회 -
0
다운로드
부가정보
다국어 초록 (Multilingual Abstract)
A new spiroketal, spirodienal B (1), was isolated from culture extracts of S. cellulosum. Its structure was elucidated by spectroscopic analysis. In addition to 1, the strain produced a second, closely related antibiotic, spirodienal. Both compounds demonstrated potent cytotoxicity against human tumor cells. Against human tumor cells such as HCT-15, the activity of 1 was more than 4000 times stronger than that of doxorubicin in terms of IC50.
참고문헌 (Reference)
1 Reichenbach, H., "The myxobacteria, in: The Prokaryotes,2nd ed" Springer Verlag 3416-3487, 1992
2 Kirst, H. A., "Structure of the spiroketal-macrolide ossamycin" 49 : 162-167, 1996
3 Jong-Woong Ahn, "Spirodienal, a New Spiroketal from Sorangium cellulosum" 대한화학회 30 (30): 742-744, 2009
4 Niggemann, J., "Spirangien A and B, highly cytotoxic and antifungal spiroketals from the myxobacterium Sorangium cellulosum: Isolation, structure elucidation and chemical modifications" 5013-5018, 200
5 Li, Xuemei, "Soraphinol C, a New Free-Radical Scavenger from Sorangium cellulosum" 한국미생물·생명공학회 18 (18): 520-522, 2008
6 Jong-Woong Ahn*, "Soraphinol B, A New Acyloin Compound Produced by Sorangium cellulosum" 대한화학회 28 (28): 1215-1216, 2007
7 Kobayashi, K., "Oligomycin E, a new antitumor antibiotic produced by Streptomyces sp. MCI-2225" 40 : 1053-1057, 1987
8 Hardt, I. H., "New natural epothilones from Sorangium cellulosum, strains So ce90/B2 and So ce90/D13: Isolation, structure elucidation, and SAR studies" 64 : 847-856, 2001
9 Skehan, P., "New colorimetric cytotoxicity assay for anticancer- drug screening" 82 : 1107-1112, 1990
10 Suarez-Gomez, B., "Isolation and structural determination of DTX-6, a new okadaic acid derivative" 64 : 1363-1364, 2001
1 Reichenbach, H., "The myxobacteria, in: The Prokaryotes,2nd ed" Springer Verlag 3416-3487, 1992
2 Kirst, H. A., "Structure of the spiroketal-macrolide ossamycin" 49 : 162-167, 1996
3 Jong-Woong Ahn, "Spirodienal, a New Spiroketal from Sorangium cellulosum" 대한화학회 30 (30): 742-744, 2009
4 Niggemann, J., "Spirangien A and B, highly cytotoxic and antifungal spiroketals from the myxobacterium Sorangium cellulosum: Isolation, structure elucidation and chemical modifications" 5013-5018, 200
5 Li, Xuemei, "Soraphinol C, a New Free-Radical Scavenger from Sorangium cellulosum" 한국미생물·생명공학회 18 (18): 520-522, 2008
6 Jong-Woong Ahn*, "Soraphinol B, A New Acyloin Compound Produced by Sorangium cellulosum" 대한화학회 28 (28): 1215-1216, 2007
7 Kobayashi, K., "Oligomycin E, a new antitumor antibiotic produced by Streptomyces sp. MCI-2225" 40 : 1053-1057, 1987
8 Hardt, I. H., "New natural epothilones from Sorangium cellulosum, strains So ce90/B2 and So ce90/D13: Isolation, structure elucidation, and SAR studies" 64 : 847-856, 2001
9 Skehan, P., "New colorimetric cytotoxicity assay for anticancer- drug screening" 82 : 1107-1112, 1990
10 Suarez-Gomez, B., "Isolation and structural determination of DTX-6, a new okadaic acid derivative" 64 : 1363-1364, 2001
11 Someno, T., "ICM0301s, New angiogenesis inhibitors from Aspegillus sp. F-1491" 57 (57): 104-109, 2004
12 Gerth, K., "Epothilones A and B: Antifungal and cytotoxic compounds from Sorangium cellulosum (Myxobacteria)" 49 : 560-563, 1996
13 Cowden, C. J., "Cancer drugs better than taxol?" 387 : 238-239, 1997
14 McCurdy, H. D., "Bergey’s Manual of Determinative Bacteriology" Williams & Wilkins 79-98, 1974
15 Litaudon, M., "Antitumor polyether macrolides: New and hemisynthetic halichondrins from the New Zealand deep-water sponge Lissodendoryx sp" 62 : 1868-1871, 1997
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분석정보
인용정보 인용지수 설명보기
학술지 이력
| 연월일 | 이력구분 | 이력상세 | 등재구분 |
|---|---|---|---|
| 2023 | 평가예정 | 해외DB학술지평가 신청대상 (해외등재 학술지 평가) | |
| 2020-01-01 | 평가 | 등재학술지 유지 (해외등재 학술지 평가) |  |
| 2010-01-01 | 평가 | 등재학술지 유지 (등재유지) | |
| 2008-01-01 | 평가 | 등재학술지 유지 (등재유지) | |
| 2006-01-01 | 평가 | 등재학술지 유지 (등재유지) | |
| 2004-01-01 | 평가 | 등재학술지 유지 (등재유지) | |
| 2001-01-01 | 평가 | 등재학술지 선정 (등재후보2차) | |
| 1998-07-01 | 평가 | 등재후보학술지 선정 (신규평가) |  |
학술지 인용정보
| 기준연도 | WOS-KCI 통합IF(2년) | KCIF(2년) | KCIF(3년) |
|---|---|---|---|
| 2016 | 1.96 | 0.2 | 1.44 |
| KCIF(4년) | KCIF(5년) | 중심성지수(3년) | 즉시성지수 |
| 1.07 | 0.87 | 0.439 | 0.05 |
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