The Chios Gum Mastic Influence on the Inhibition of Intraoral Microorganisms Proliferation

다국어 초록 (Multilingual Abstract)

Objective: A series of experiments were performed to evaluate the inhibition effect of mastic for proliferation of intraoral microorganism, identified as the origin of dental caries and periodontal disease.


Materials and Methods: Bacterial incubation culture plate containing mastic (each plate was partitioned off several portions and each portion had different concentration of mastic) were prepared. Intraoral microorganism, identified as the origin of dental caries and periodontal disease were inoculated to the plates. After culturing them during 48-72 hours at 37oC, It was evaluated whether strains were proliferated or not.


Results: MIC/MBC of Streptococcus mutans, strong cariogenic bacteria were 8/32 mg/mL and both MIC and MBC of S. Sobrinus, regarded as considerable strong cariogenic bacteria were 8 mg/mL. MIC/MBC of Lactobacillus casei were 8/32 mg/mL. MIC/MBC of S. mitis and S. oralis were 1 mg/mL and 2 mg/mL. MIC/MBC of S. sanguis were 4/8 mg/mL. MIC/MBC of S. salivarius were 4/8 mg/mL. Results of anaerobic bacteria, cause periodontitis are as follow. MIC/MBC of Porphyromonas gingivalis were 4/8 mg/mL, both MIC and MBC of Fusobacterium nucleatum were 32 mg/mL. MIC/MBC of Porphyromonas endocarditis were 16/32 mg/mL. Both MIC and MBC of Actinobacillus actinomycetemcomitans were 8 mg/mL. Both MIC and MBC of Actinomyces naeslundii were 32 mg/mL. MIC/MBC of Actinomyces dontolyticus were 8/16 mg/mL.


Conclusion: According to the results of our experiments, it can be suggested that mastic have the inhibition effect on proliferation of intraoral microorganism, identified as the origin of dental caries and periodontal disease.

참고문헌 (Reference)

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