To investigate cortisone activity on the serum electrolytes(Na Cl & R) in the experimental dogs undergone vagotomy, subdiaphragmatic and antrectomy, cortisone acetate was given intramuscularly, 2.5㎎. per ㎏. of body weight, on the 90th postoperativ...
To investigate cortisone activity on the serum electrolytes(Na Cl & R) in the experimental dogs undergone vagotomy, subdiaphragmatic and antrectomy, cortisone acetate was given intramuscularly, 2.5㎎. per ㎏. of body weight, on the 90th postoperative day and blood sample were taken 8 times at 30 minutes intervals.
As for control group, gastrostomized dogs were used.
Results are as follows:
1) In vagotomy group, after the administion of cortisone, the mean K value was 4.7±0.11 mEq/L. or 9.3% increase of control, the mean Na value 142.1±1.54 mEq/L. or 1.7% decrease of control and the mean Cl value 113.4±0.74 mEq/L. or 5.3% increase of control.
2) In antrectomy group, after the administration of cortisone, the mean K value was 4.8±0.33 mEq/L. or 9.3% increase of control, the mean Na value 141.5±0.56 mEq/L. or 2.1% decrease of control and the mean value Cl 114.3±0.51 mEq/L. or 6.1% increase of control.