鼻茸患者에 있어서 IgE値 및 末梢血液好酸球의 變化 = Evaluation of IgE Levels and Peripheral Blood Eosinophil Counts in Nasal Polyp

국문 초록 (Abstract)

1983年 7月부터 1984年 6月까지 慶北大學校 醫科大學 附屬病院 耳鼻咽喉科에서 手術을 받은 鼻茸患者 60例 및 慢性副鼻洞炎患者 30例에서 알레르기 檢査, 血淸 IgE値, 鼻茸液 IgE値, 末梢血液好酸球値를 檢査하여 이들의 相互關係를 比較 檢討한 結果 다음과 같은 結果를 얻었다.
鼻茸液 IgE値는 상당히 增加되어 있었으며 특히 알레르기 집단에서 더욱 높았다.
血淸 IgE値는 鼻茸患者群이 대조군인 副鼻洞炎患群보다 약간 높았으며 알레르기 집단과 非알레르기 집단간에도 약간의 차이가 있었다.
鼻茸患者群중에서 병해 病歷 및 알레르기 皮膚反應檢査陽性인 患者는 10名(16.7%)이었다.
末梢血液好酸球增多는 鼻茸患者群에서 조금 높았다.
이상의 結果를 종합하여 볼 때 鼻茸의 발생기전에 알레르기가 여러 요인중 일부를 담당한다고 사료된다.

다국어 초록 (Multilingual Abstract)

From the survey of relationship between nasal polyposis and nasal allergy the IgE content was measured in serum and nasal polyp fluid of 60 patients with nasal polyp who had admitted to Kyungpook medical hospital during last one year. The IgE content in serum was also measured in patients with chronic paranasal sinusitis who had chosen as control group. In addition, all patients were studied for peripheral blood eosinophil counts.
The results were as follows:
The level of IgE in polyp fluid was higher than serum level.
The IgE content of serum was somewhat higher in nasal polyp patient especially in allergic group than paranasal sinusitis group.
Nasal polup patients with allergic history and positive skin test were obtained in 10 cases(16.7%) which was higher than the levels of chronic paranasal sinusitis.
Peripheral blood eosinophil was higher in patient with nasal polyp than patient without nasal polyp.
As above results it seems that allergy is one of factors which contribute to the development of nasal polyp.