The intramolecular, stereoselective addition of 1-vinylcyclopropanols to tethered aldehydes has been achieved under mild conditions. Thus, sequential application of the titanium-mediated cyclopropanation of α,β-unsaturated esters and the electrophil...
The intramolecular, stereoselective addition of 1-vinylcyclopropanols to tethered aldehydes has been achieved under mild conditions. Thus, sequential application of the titanium-mediated cyclopropanation of α,β-unsaturated esters and the electrophilic cyclization of the aldehydetethered cyclopropanol products provides the facile formation of carbocyclic rings.