의학강좌 : 아나필락시스의 관리 = Current Clinical Practice : Management of Anaphylaxis

다국어 초록 (Multilingual Abstract)

Anaphylaxis is a life-threatening systemic hypersensitivity reaction with a rapid onset. All healthcare professionals should be familiar with its recognition and management. The clinical diagnosis is important. It involves the sudden onset of characteristic symptoms and signs within minutes to hours after exposure to a known or potential trigger, often followed by rapid progression over hours. Symptoms usually involve two or more body systems, including the skin and mucous membranes, and respiratory, gastrointestinal, cardiovascular, and central nervous systems. Prompt initial basic treatment with intramuscular epinephrine in the mid-anterolateral thigh can be life-saving. Simultaneously, it is important to place the patient in a supine position, call for help when indicated, provide supplemental oxygen, start intravenous fluid, and provide cardiopulmonary resuscitation as required, while monitoring the patient’s vital signs and oxygenation status. Antihistamines and glucocorticoids are not initial treatments of choice. For self-management, patients at risk of anaphylaxis should carry epinephrine auto-injectors, have personalized emergency action plans, and follow-up with a physician about preventing anaphylaxis recurrence. Patient and caregiver training and education are essential in the management of anaphylaxis. (Korean J Med 2015;89:413-417)

참고문헌 (Reference)

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3 예영민, "Predictors of the Severity and Serious Outcomes of Anaphylaxis in Korean Adults: A Multicenter Retrospective Case Study" 대한천식알레르기학회 7 (7): 22-29, 2015

4 Brown SG, "Middleton’s Allergy: Principles and Practice Vol. 2" Saunders 1237-1259, 2013

5 Muraro A, "Anaphylaxis: guidelines from the European Academy of Allergy and Clinical Immunology" 69 : 1026-1045, 2014