n-6계 linoleic acid의 함량이 높은 옥수수유 및 n-3계 linolenic acid의 함량이 높은 들깨유와 함유된 다가불포화지방산을 공역이중결합 유도체화 처리한 옥수수유 및 들깨유가 흰쥐의 혈청 지질개...
http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
https://www.riss.kr/link?id=A103699488
김소영 ; 김성희 ; 김경업 ; Kim, So-Young ; Kim, Sung-Hee ; Kim, Gyeong-Eup
2007
Korean
KCI등재,SCOPUS
학술저널
1120-1127(8쪽)
1
0
상세조회0
다운로드국문 초록 (Abstract)
n-6계 linoleic acid의 함량이 높은 옥수수유 및 n-3계 linolenic acid의 함량이 높은 들깨유와 함유된 다가불포화지방산을 공역이중결합 유도체화 처리한 옥수수유 및 들깨유가 흰쥐의 혈청 지질개...
n-6계 linoleic acid의 함량이 높은 옥수수유 및 n-3계 linolenic acid의 함량이 높은 들깨유와 함유된 다가불포화지방산을 공역이중결합 유도체화 처리한 옥수수유 및 들깨유가 흰쥐의 혈청 지질개선에 미치는 영향을 비교 검토하기 위하여 S.D.계 숫 흰쥐에게 돈지 식이를 대조군으로 하고 옥수수유 10%, 들깨유 10%, 유도체화 처리한 옥수수유 10% 및 유도체화 처리한 들깨유 10%을 급여하여 4주간 실험 사육한 후 혈청 지질성분을 분석하였다. 유도체화 처리한 옥수수유(TCO)는 가스 크로마토그래피에 의해 3개의 linoleic acid의 유도체가 확인되었고 유도체화 처리한 들깨유(TPO)에서는 5개의 linolenic acid의 유도체가 확인되었다. 체중증가량 및 식이섭취량은 유도체화 처리한 옥수수유 및 들깨유 급여군에서 유의성 있게 낮았다. 혈청 총콜레스테롤 농도는 대조군에 비해 전실험군에서 유의성 있게 낮았으며, 특히 유도체화 처리한 옥수수유 및 들깨유 급여군에서 더욱 낮았다. HDL-콜레스테롤 농도는 대조군에 비해 전실험군에서 유의적으로 높았다. 혈청 LDL 및 LDL-콜레스테롤 농도는 대조군에 비해 전실험군에서 유의성 있게 낮았으며 유도체화 처리한 옥수수유 및 들깨유 급여군에서 더욱 낮은 경향을 보였고, 특히 유도체화 처리한 들깨유 급여군에서 가장 낮았다. VLDL 농도는 대조군에 비해 전실험군에서 유의성 있게 낮았으며, chylomicron 농도는 유도체화 처리한 유지 급여군에서 유의성 있게 낮았고 특히 유도체화 처리한 들깨유 급여군에서 가장 낮았다. 혈청 유리콜레스테롤 농도는 대조군에 비해 전 실험군간에 유의적인 차이는 없는 반면 유도체화 처리한 옥수수유 및 들깨유 급여군에서 약간 낮았다. 혈청 중성지질 농도는 대조군에 비해 전실험군에서 유의성 있게 낮았으며, 특히 유도체화 처리한 들깨유 급여군에서 가장 낮았다. 인지질 농도는 옥수수유 급여군이 대조군에 비해 약간 높게 나타난 반면 유도체화 처리한 유지 급여군은 약간 낮은 수준이었다. 이상의 결과 n-6계 linoleic acid의 함량이 높은 옥수수유 및 n-3계 linolenic acid 함량이 높은 들깨유의 공역이중결합유도체의 섭취는 혈중 총콜레스테롤, LDL-콜레스테롤, chylomicron 및 중성지질 농도를 감소시킴으로써 혈청 지질 개선효과가 있는 것으로 나타났으며, 특히 n-3계 들깨유의 공역이중결합 유도체 급여군이 혈청 지질 개선효과가 가장 큰 것으로 나타났다.
다국어 초록 (Multilingual Abstract)
This study was designed to examine the effects of n-6 PUFA rich corn oil, n-3 PUFA rich perilla oil and their conjugated double bond derivatives on serum lipids status in rats. Experimental diets containing lard (control), corn oil (CO), perilla oil (...
This study was designed to examine the effects of n-6 PUFA rich corn oil, n-3 PUFA rich perilla oil and their conjugated double bond derivatives on serum lipids status in rats. Experimental diets containing lard (control), corn oil (CO), perilla oil (PO), conjugated double bond derivatives of n-6 PUFA rich corn oil (TCO) and n-3 PUFA rich perilla oil (TPO) at the level of 10% (w/w) were fed to male Sprague Dawley rats for 4 weeks. TCO was found to have three derivatives of linoleic acid and TPO had five derivatives of linolenic acid by GC. Serum total cholesterol levels were significantly lower in the all experimental groups than in the control group, and particularly, the lowest in TCO and TPO groups. HDL-cholesterol concentrations were a little higher in the all experimental groups than in the control group, and TCO and TPO groups were not significantly different from CO and PO groups. Serum LDL, LDL-cholesterol, chylomicron and triglyceride concentrations were significantly lower in the all experimental groups than in the control group, remarkably lower in TCO group and particularly, the lowest in the TPO group. Serum free cholesterol and cholesteryl ester concentrations were lower in TCO and TPO groups than in CO and PO groups. From the above research, TCO and TPO groups were effective on the improvement of the lipid compositions in serum and particularly, TPO group was the most effective on the improvement of serum lipids.
참고문헌 (Reference)
1 加藤敏光, "ラットの 食餌性 コレステロ-血症に 及しはすスビ ルリナの 影響" 37 : 323-332, 1984
2 Oakenfull DG, "The role of saponin on lower plasma cholesterol concentration" 42 : 209-216, 1979
3 Szymczyk B, "The effects of feeding conjugated linoleic acid(CLA)on rat growth performance, serum lipoproteins and subsequent lipid composition of selected rat tissues" 80 : 1553-1558, 2000
4 Von Lossonczy TO, "The effect of a fish diet on serum lipids in healthy human subject" 31 : 1340-1346, 1978
5 Connor WE, "The dietary treatment of hyperlipidemia. Rationale, technique and efficacy" 66 : 485-518, 1982
6 Van Doornen LJ, "Stress, personality and serum cholesterol level" 8 : 24-29, 1982
7 Recknagel RO, "Spectrophotometric detection of lipid conjugated dienes" 105 : 331-337, 1984
8 Steel RGD, "Principles and procedures of statistics: a biometrical approach" McGraw-Hill 187-188, 1980
9 Bang HO, "Plasma lipids and lipoproteins in greenland west coast Eskimos" 192 : 85-94, 1972
10 Schwartz CJ, "Pathogenesis of the atherosclerotic lesion : implications for diabetes mellitus" 15 : 1156-1167, 1992
1 加藤敏光, "ラットの 食餌性 コレステロ-血症に 及しはすスビ ルリナの 影響" 37 : 323-332, 1984
2 Oakenfull DG, "The role of saponin on lower plasma cholesterol concentration" 42 : 209-216, 1979
3 Szymczyk B, "The effects of feeding conjugated linoleic acid(CLA)on rat growth performance, serum lipoproteins and subsequent lipid composition of selected rat tissues" 80 : 1553-1558, 2000
4 Von Lossonczy TO, "The effect of a fish diet on serum lipids in healthy human subject" 31 : 1340-1346, 1978
5 Connor WE, "The dietary treatment of hyperlipidemia. Rationale, technique and efficacy" 66 : 485-518, 1982
6 Van Doornen LJ, "Stress, personality and serum cholesterol level" 8 : 24-29, 1982
7 Recknagel RO, "Spectrophotometric detection of lipid conjugated dienes" 105 : 331-337, 1984
8 Steel RGD, "Principles and procedures of statistics: a biometrical approach" McGraw-Hill 187-188, 1980
9 Bang HO, "Plasma lipids and lipoproteins in greenland west coast Eskimos" 192 : 85-94, 1972
10 Schwartz CJ, "Pathogenesis of the atherosclerotic lesion : implications for diabetes mellitus" 15 : 1156-1167, 1992
11 Allexander JJ, "Oxygen radicals alter LDL permeability and uptake by an endothelial-smooth muscle cell bilayer" 51 : 361-367, 1991
12 Ranazit P, "On the mechanism of hypocholesterolemic effects of polyunsaturated lipids" 17 : 155-171, 1980
13 AOAC, "Official Methods of Analysis. 14th ed" Association of official analytical chemists 223-, 1980
14 Anderson JW, "Oat-bran cereal lowers serum total and LDL-cholesterol in hypercholesterolemic men" 52 : 495-499, 1990
15 Steinberg D, "Lipoproteins and atherogenesis" 264 : 3047-3052, 1990
16 Kinnunen PKJ, "Lipoprotein lipase and hepatic endothelial lipase" 11 : 65-105, 1983
17 Bang HO, "Lipid metabolism and ischemic heart disease in Greenland Eskimos, In Advances in nutrition research. Vol 3" Plenum Press 1-22, 1980
18 Phillips NR, "Levels and interrelationships of serum and lipoprotein cholesterol and triglycerides. Association with adiposity and the consumption of ethanol, tobacco and beverages containing caffeine" 1 : 13-24, 1982
19 O'Brien BC, "Interrelated effects of food lipids on steroid metabolism in rats" 107 : 1444-1454, 1977
20 Illingworth DR, "Inhibition of low density lipoprotein synthesis by dietary ω-3 fatty acids in humans" 4 : 270-275, 1984
21 Ha YL, "Inhibition of benzo(a)pyrene-induced mouse forestomach neoplasia by conjugated dienoic derivatives of linoleic acid" 50 : 1097-1101, 1990
22 Otamiri T, "Increased lipid peroxidation in malignant tissues of patients with colorectal cancer" 64 : 422-425, 1989
23 Williams P, "High-density lipoprotein and coronary risk factors in normal men" 1 : 72-75, 1979
24 Dyerberg J, "Fatty acid composition of the plasma lipids in Greenland Eskimos" 28 : 958-966, 1975
25 Hernick AS, "Estimating carbonyl compounds in rancid fats and food" 31 : 88-91, 1954
26 Lee JH, "Effects of various combinations of ω3 and ω6 PUFA with SFA on serum lipid levels and eicosanoid production in rats" 34 : 117-129, 1988
27 Summerfield FW, "Effect of dietary polyunsaturated fats and vitamin E on aging and peroxidative damage to DNA" 233 : 408-416, 1984
28 Faidley ED, "Effect of dietary fat source on lipoprotein composition and plasma lipid concentrations in pigs" 120 : 1126-1133, 1990
29 Garg ML, "Effect of dietary cholesterol and ω6 or ω3 fatty acids on lipid composition and Δ5-desaturase activity of rat liver microsomes" 118 : 661-668, 1988
30 Mitchell PL, "Effect of conjugated linoleic acid isomers on lipoproteins and atherosclerosis in the Syrian Golden hamster" 1734 : 269-276, 2005
31 Takahashi K, "Effect of a mixture of conjugated linoleic acid isomers on growth performance and antibody production in broiler chicks" 89 : 691-694, 2003
32 Applebaum-Bowden D, "Down regulation of the low density lipoprotein receptor by dietary cholesterol" 39 : 360-367, 1984
33 Kobatake Y, "Differential effects of dietary eicosapentaenoic and docosahexaenoic fatty acids on lowering of triglyceride and cholesterol levels in the serum of fats on hypercholesterolemic diet" 30 : 357-372, 1984
34 Huff MW, "Dietary fish oil increases conversion of very low density lipoprotein apoprotein B to low density lipoprotein" 9 : 58-66, 1989
35 Kobatake Y, "Dietary effect of ω-3 type polyunsaturated fatty acid on serum and liver lipid level in rats" 29 : 11-21, 1983
36 Wilson TA, "Conjugated linoleic acid reduces early aortic atherosclerosis greater than linoleic acid in hypercholesterolemic hamsters" 20 : 1795-1805, 2000
37 Pariza MW, "Conjugated linoleic acid and atherosclerosis in rabbits" 108 : 2519-2529, 1994
38 Pariza MW, "Conjugated dienoic derivatives of linoleic acid. A new class of anticarcinogens" 7 : 169-171, 1990
39 Pariza MW, "Conjugated dienoic derivatives of linoleic acid : mechanism of anticarcinogenic effect" 347 : 217-221, 1990
40 Kannel WB, "Cholesterol in the prediction of atherosclerotic disease" 90 : 85-91, 1979
41 Ha YL, "Anticarcinogens from fried ground beef : heat-altered derivatives of linoleic acid" 8 : 1881-1887, 1987
42 Ha YL, "Anticarcinogenic conjugated dienoic derivatives of linoleic acid found in grilled ground beef: isolation, identification, and mechanism of action" 442-445, 1990
43 Kim YR, "A simple method for the preparation of highly pure conjugated linoleic acid(CLA)synthesized from safflower seed oil" 5 : 10-14, 2000
44 Harris WS, "A comparative reductions of the plasma lipids and lipoproteins by dietary polyunsaturated fats : Salmon oil versus vegetable oils" 32 : 179-184, 1983
오만둥이(Styela plicata) 추출물의 in vitro 세포독성 효과
등대풀(Euphorbia helioscopia) 용매 추출물의 항산화 및 항균활성
가죽나무(Ailanthus altissima) 물 추출물의 항산화 활성과 Tyrosinase 저해
학술지 이력
연월일 | 이력구분 | 이력상세 | 등재구분 |
---|---|---|---|
2023 | 평가예정 | 해외DB학술지평가 신청대상 (해외등재 학술지 평가) | |
2020-01-01 | 평가 | 등재학술지 유지 (해외등재 학술지 평가) | |
2014-06-24 | 학회명변경 | 한글명 : 한국식품영양과학회지 -> 한국식품영양과학회영문명 : Journal of the Korean Society of Food Science and Nutrition -> The Korean Society of Food Science and Nutrition | |
2014-04-02 | 학회명변경 | 한글명 : 한국식품영양과학회 -> 한국식품영양과학회지영문명 : 미등록 -> Journal of the Korean Society of Food Science and Nutrition | |
2011-01-01 | 평가 | 등재학술지 유지 (등재유지) | |
2009-01-01 | 평가 | 등재학술지 유지 (등재유지) | |
2007-01-01 | 평가 | 등재학술지 유지 (등재유지) | |
2005-01-01 | 평가 | 등재학술지 유지 (등재유지) | |
2002-07-01 | 평가 | 등재학술지 선정 (등재후보2차) | |
2000-01-01 | 평가 | 등재후보학술지 선정 (신규평가) |
학술지 인용정보
기준연도 | WOS-KCI 통합IF(2년) | KCIF(2년) | KCIF(3년) |
---|---|---|---|
2016 | 1.03 | 1.03 | 1.13 |
KCIF(4년) | KCIF(5년) | 중심성지수(3년) | 즉시성지수 |
1.18 | 1.2 | 1.993 | 0.21 |