Lemierre 증후군 1례 = A Case of Lemierre Syndrome

다국어 초록 (Multilingual Abstract)

Lemierre syndrome is a rare syndrome caused by an acute pharyngitis with secondary septic thrombophlebitis of the internal jugular vein and metastatic infections. Although mortality from Lemierre syndrome is low, it remains a potentially lifethreatening disease that requires careful consideration, as its early diagnosis and treatment is essential to prevent metastatic infection. We report a case of a 19-year-old woman who presented with a sore throat and right upper quadrant pain.
Abdominal and pelvic computerized tomography (CT)showed acalculous cholecystitis with hepatosplenomegaly.
The chest CT showed septic emboli in both lung fields and the neck CT revealed thrombosis in the left internal jugular vein.
The patient was treated with antibiotics. After nine days, the chest CT showed a further increase in the size of the septic embolism and the patient was treated with anticoagulants.
After 23 days, the size of septic emboli in the lung significantly decreased and the patient was discharged.

참고문헌 (Reference)

1 Chirinos JA, "The evolution of Lemierre syndrome: report of 2 cases and review of the literature" 81 : 458-462, 2002

2 Beldman TF, "Septic arthritis of the hip by Fusobacterium necrophorum after tonsillectomy: A form of Lemierre syndrome?" 156 : 856-857, 1997

3 Lemierre A, "On certain septicaemias due to anaerobic organisms" 1 : 1701-1703, 1936

4 Morizono S, "Lemierre’s syndrome: Porphyromonas asaccharolytica as a putative pathogen" 44 : 350-353, 2005

5 Kuppalli K, "Lemierre’s syndrome due to Fusobacterium necrophorum" 12 : 808-815, 2012

6 Armstrong AW, "Lemierre’s syndrome" 2 : 168-173, 2000

7 Lustig LR, "Lemierre´’s syndrome: two cases of postanginal sepsis" 112 : 767-772, 1995

8 Carlson ER, "Lemierre's syndrome: two cases of a forgotten disease" 52 : 74-78, 1994

9 Lu MD, "Lemierre syndrome following oropharyngeal infection : a case series" 22 : 79-83, 2009

10 Williams A, "Lemierre syndrome : a complication of acute pharyngitis" 45 : 51-57, 1998

11 Koay CB, "Lemiere syndorme-a forgotten complication of acute tonsillitis" 109 : 657-661, 1995

12 Hagelskjaer LH, "Kristensen. Incidence and clinical epidemiology of necrobacillosis, including Lemierre’s syndrome, in Denmark 1990-1995" 17 : 561-565, 1998

13 Brook I, "Infections caused by beta-lactamase-producing Fusobacterium spp. in children" 12 : 532-533, 1993

14 Hagelskjaer Kristensen L, "Human Necrobacillosis, with Emphasis on Lemierre’s syndrome" 31 : 524-532, 2000

15 Tan ZL, "Fusobacterium necrophorum infections: virulence factors, pathogenic mechanism, and control measures" 20 : 113-140, 1996

16 Amoako KK, "Comparison of extracellular enzymes of Fusobacterium necrophorum subsp. necrophorum and Fusobacterium necrophorum subsp. funduliforme" 31 : 2244-2247, 1993

17 David H, "A 21-year-old man with fever and abdominal pain after recent peritonsillar abscess drainage" 27 : 515-, 2009