만성 경막하 혈종(Chronic subdural hematoma, CSDH)에 대한 오령산 증례보고 2례 = Two Case Studies of the Use of Oreong-san for a Chronic Subdural Hematoma

다국어 초록 (Multilingual Abstract)

We describe the cases of two patients with chronic subdural hematomas who were treated with Oreong-san. The patients' symptoms improved, as verified by brain computed tomography imaging. Oreong-san may control membrane permeability by inhibiting the aquaporin channel of the outer membrane of a hematoma. We speculate that hydrostatic modulation is a key mechanism underlying the effectiveness of Oreong-san in the treatment of subdural hematomas.

참고문헌 (Reference)

1 Utsuki S, "Role of saireito in postoperative chronic subdural hematoma recurrence prevention" 29 (29): 137-142, 2012

2 Ambrosetto C, "Post-traumatic subdural hematoma. Further observations on nonsurgical treatment" 6 (6): 287-292, 1962

3 Thotakura AK, "Nonsurgical treatment of chronic subdural hematoma with steroids" 84 (84): 1968-1972, 2015

4 Suzuki J, "Nonsurgical treatment of chronic subdural hematoma" 33 (33): 548-553, 1970

5 Voelker JL, "Nonoperative treatment of chronic subdural hematoma" 11 (11): 507-513, 2000

6 Cho KH, "Herbal Medicine, Oreongsan for Recurrent Chronic Subdural Hematoma: A Case Report" 13 (13): 139-141, 2016

7 Okamura A, "Evaluation of recurrence factors and Gorei-san administration for chronic subdural hematoma after percutaneous subdural tapping" 62 (62): 77-82, 2013

8 Mitsuhashi T, "Efficacy of goreisan for asymptomatic bilateral and unilateral chronic subdural hematoma" Traditional & Kampo Medicine 2015

9 Kurita T, "Effects of Goreisan: a traditional Japanese kampo medicine, on aquaporin 1,2,3,4 and V2R mRNA expression in rat kidney and forebrain" 11 : 30-38, 2011

10 Utsuki S, "Effect of postoperative administration of Saireito for bilateral chronic subdural hematomas" 2 (2): 285-288, 2011

11 Yasunaga H, "Effect of Japanese herbal Kampo medicine goreisan on reoperation rates after burr-hole surgery for chronic subdural hematoma: analysis of a national inpatient database" 2015

12 Yang W, "Chronic Subdural Hematoma: Epidemiology and Natural History" 28 (28): 205-210, 2017

13 Weigei R, "Angiotensin converting enzyme inhibition for arterial hypertension reduces the risk of recurrence in patients with chronic subdural hematoma possibly by an anti-angiogenic mechanism" 61 (61): 788-793, 2007

14 Hayashi A, "A New Oriental Medical Approach To Eliminate Brain Edema Complicated With Malignant Brain Tumors: Efficacy Of Goreisan(an Aquaporin Inhibiter)" 12 (12): 27-, 2010