만성 위염에서 Helicobacter Pylori 에 대한 간편 검사법들의 진단을 비교 = Comparison of Simple Diagnostic Methods for Helicobacter Pylori Gastritis

다국어 초록 (Multilingual Abstract)

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다국어 초록 (Multilingual Abstract)

Background: Helicobacter pylori has been implicated in the pathogenesis of chronic active gastritis, peptic ulcer disease, gastric cancer. The rapid identification of this organism may depend upon histologic diagnosis, because culture methods are complex and require a minimum of seven days in to identifying a negative specimen. The purpose of this study was to determine which simple test u to identify this organism was the most cost-effective and easiest to perform and interpret on a routine basis. Methods: The authors evaluated the use of rapid urease test (CLO test(R)), Bio-Rad G.A.P. IgG and 1gM test to detect Helicobacter pylori in 80 patients with chronic gastritis, Results: Sixty patients (75%) had H.pylori identifiable in Giemsa stains, Also, sixty patients (75%) had positive rapid urease tests, sixty eight patients (85%) had positive serum IgG tests, and fifty two patients had positive serum IgM tests. The sensitivities of the methods were as follows: 93% for the rapid urease test, 90g for the serum IgG test, and 63% for the serum IgM test. The specificities of the methods were as follows: 80% for the rapid urease test, 35% for the serum IgG test, and 15% for the serum IgM test. The accuracies of the methods were as follows: 90% for the rapid urease test, 76% for the serum IgG test, and 50% for the serum IgM test, Conclusion: The rapid urease test used in this study is a useful, highly specific screening test; That the serum IgG test has limited specificity.