Giant Brunner’s Gland Adenoma of the Proximal Jejunum Presenting as Iron Deficiency Anemia and Mimicking Intussusceptions

다국어 초록 (Multilingual Abstract)

Brunner’s gland adenoma is a rare benign proliferative lesion developing most commonly in the posterior wall of the duodenum. It is usually small in size and asymptomatic. Depending on its size or location, however, the clinical manifestations of this tumor may be variable from nonspecific symptoms to gastrointestinal bleeding or obstruction. Brunner’s gland adenoma in the proximal jejunum is extremely rare. We report a very rare case of giant Brunner’s gland adenoma developing in the proximal jejunum which presented as iron deficiency anemia and mimicked intussusceptions on radiologic studies.

참고문헌 (Reference)

1 Feyrter F, "Über wucherungen der brunnerschen drüsen" 293 : 509-526, 1934

2 Krause WJ, "The effect of surgical ablation of Brunner’s glands on the proximal duodenal mucosa" 166 : 111-115, 1988

3 Sleisenger MH, "Sleisenger & Fordtran’s Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, Management. 8th ed" Saunders 2006

4 Stolte M, "Relationship between diseases of the pancreas and hyperplasia of Brunner’s glands" 394 : 75-87, 1981

5 Hirasaki S, "Pedunculated Brunner’s gland hamartoma of the duodenum causing upper gastrointestinal hemorrhage" 15 : 373-375, 2009

6 Palanivelu C, "Laparoscopic antrectomy for a proximal duodenal Brunner gland hamartoma" 13 : 110-115, 2009

7 Chen YY, "Hemoclip-assisted polypectomy of large duodenal Brunner’s gland hamartoma" 51 : 1670-1672, 2006

8 Henken EM, "Hamartoma of Brunner’s gland causing partial obstruction of the ileum" 34 : 73-74, 1983

9 El Faleh I, "Gastric outlet obstruction by Brunner’s gland hyperplasia in an 8-year-old child" 44 : E21-E24, 2009

10 Christie AC., "Duodenal carcinoma with neoplastic transformation of the underlying Brunner’s glands" 7 : 65-67, 1953

11 Fujimaki E, "Brunner’s gland adenoma with a focus of p53-positive atypical glands" 35 : 155-158, 2000

12 Mayoral W, "Biliary obstruction and pancreatitis caused by Brunner’s gland hyperplasia of the ampulla of Vater: a case report and review of the literature" 32 : 998-1001, 2000

13 Cruveilhier J, "Anatomie Pathologique du Corps Humain" Bailliere 1835-,