RISS 검색 - 국내학술지논문 상세보기

다국어 초록 (Multilingual Abstract)

Objectives The goal of this review was to investigate clinical, experimental and literature studies of Korean medicine on atopic dermatitis (AD) of Korean children in Korean medicine literature, seeking for the better research methods for more effective treatments. Methods Electronic investigations were practiced on AKOP (The Association of Korean Oriental Pediatrics, http://www.akop.or.kr) to collect theses which were published by J Pediatr Korean Med. The key word 'Atopy' was used for searching to ensure that every related thesis was collected. The publication date was limited from 1996 to 2016. The selected literatures were assessed mainly according to distributions of study type, publication year, scale, treatment and its efficacy. Results 55 papers were selected from 59 studies. In these collected 55 related theses, there were 29 experimental studies (52.73%), 18 clinical studies (32.73%), 8 review studies (14.55%). In the 29 experimental studies, there were 20 studies (68.97%) using NC/Nga mouse as subjects. The mite antigen was used to trigger AD by 8 studies (27.59%). The studies have been utilizing DNCB and DNFB instead of mite antigen since 2011. All the experimental studies showed that the Korean medicine was effective in AD. In total 18 clinical studies, 3 studies (16.67%) were case reports, only 1 thesis (5.56%) was conducted by case control study and the rest were case series studies. 7 studies (38.89%) of 18 studies diagnosed AD according to Hanifin and Rajka's diagnostic criteria (1980), only 1 study (5.56%) according to the Korean standard and the rest 10 studies (55.56%) didn't mention diagnostic criteria. 12 clinical studies (66.67%) showed efficacy in treating AD. There were 10 studies (55.56%) only employing internal treatments and 1 thesis (5.56%) didn't mention the exact prescription. Naesowhajungtang-kamibang, Saenghyeoryunbue-um were used 3 times (16.67%) as the internal medicine respectively. 5 theses (27.78%) were combined with acupuncture therapy. Hegu (LI4), Sanyinjiao (SP6) were used in 4 theses, and Taichong (LR3), Quchi (LI11), Zusanli (ST36) in 3 theses. The number of acupoints chosen from The Spleen meridian of Foot-Taiyin was the largest. There were 8 review theses. 2 were about the foreign oriental medicine, 3 were about the external medicine or external treatment methods, and 3 other studies were about severity scoring systems, the methodological study in the latest clinical study, overview for pattern and results of herbal medicine-derived AD clinical researches. Conclusions The experimental studies and clinical studies showed the effectiveness of Korean medicine treatments. However, this study still needs improving by conducting more comparative studies and using better research methods, in order to find more effective treatments to improve clinical efficacy.

참고문헌 (Reference)

1 서희연, "理中湯이 Mite antigen으로 유발된 NC/Nga 생쥐의 아토피 피부염에 미치는 영향" 대한한방소아과학회 25 (25): 1-27, 2011

2 이진화, "連翹 n-BuOH 분획물의 아토피 피부염 억제 효과" 대한한방소아과학회 30 (30): 1-30, 2016

3 박두병, "凉血除濕湯이 DNCB로 유도된 NC/Nga mice의 아토피 피부염에 미치는 영향" 대한한방소아과학회 23 (23): 263-291, 2009

4 김윤희, "호마자 추출물이 NC/Nga 생쥐의 아토피 피부염에 미치는 영향" 대한한방소아과학회 29 (29): 39-66, 2015

5 임영권, "한약의 아토피 피부염 치료에 대한 예비 임상 연구" 대한한방소아과학회 20 (20): 129-141, 2006

6 김윤희, "한약을 이용한 아토피 임상연구의 경향에 관한 연구" 대한한방소아과학회 26 (26): 53-61, 2012

7 조민서, "한방 병원 소아과를 내원한 소아 아토피 피부염 환자 실태에 관한 조사" 대한한방소아과학회 25 (25): 8-14, 2011

8 차호열, "하태독법 중 황련감초법이 DNFB로 유발된 NC/Nga 생쥐의 아토피 피부염에 미치는 영향" 대한한방소아과학회 29 (29): 97-107, 2015

9 신미란, "캠프 형식의 입원 치료를 받은 소아 아토피피부염 환자 6례" 대한한방소아과학회 28 (28): 40-55, 2014

10 윤혜준, "저출력 레이저 치료(LLLT)가 아토피 피부염의 증상 완화에 미치는 영향" 대한한방소아과학회 23 (23): 193-206, 2009