Purpose: Among colorectal neoplasms, laterally spreading tumors (LSTs) are defined as tumors over 10mm in diameter that are low in height and grow superficially. We analyzed the clinicopathologic characteristics of LSTs in colorectum and the outcomes ...
Purpose: Among colorectal neoplasms, laterally spreading tumors (LSTs) are defined as tumors over 10mm in diameter that are low in height and grow superficially. We analyzed the clinicopathologic characteristics of LSTs in colorectum and the outcomes of endoscopic treatments for LSTs.
Subject and Methods: One hundred twenty one LSTs were analyzed according to their endoscopic and pathologic findings.
Results: The most frequent location was asceding colon(41.3%), followed by rectum(24.8%). Morphologic types were GH types 28.0%(34/121), MN types 33.1% (41/121), FL types 19.8% (24/121), and PD types 18.1% (34/121). Sixty eight LSTs (56.2%) were less than 20 mm in diameter, 28(23.1%) were 20~30 mm, 14 (11.6%) were 30-40mm, and 11 (9.1%) were larger than 40 mm. The overall malignancy rate was 19.8% (24/121). Malignancy rates were 16.7% (16/96) in the lesions less than 30 mm, and 32% (8/25) in larger than 30 rom. Malignancy rates were 2.9% (1/34) in GH type, 31.7%(3/41) in MN type, 8.3% (2/24) in FL type, and 36.3%(8/22) in PD type.
Conclusions: LSTs larger than 30 rom had high malignant potential. Furthermore, LSTs showed different clinicopathologic characteristics depending on the morphologic classification. MN or PD type had higher malignant potential than GH or FL type.