梅毒血淸反應의 比較檢討 : 第1報 MHA-TP法, FTA-ABS法의 術式과 一部成績 Ⅰ. TPHA and FTA-ABS Test, and Results in Part = Comparison of Serological Reactions of Syphilis on 27 Sera

국문 초록 (Abstract)

VDRL陽性血淸 24例와 VDRL陰性血淸 3例 總 27例를 對象으로 TPHA 및 FTA-ABS法을 倂行 實施하여 成績을 比較하여 보았다. VDRL陽性血淸 24例中 21例(87.8%)가 三者 共히 陽性을 나타내었으며 3例는 TPHA陰性으로서 이 中 FTA-ABS陽性이 1例(33.3%)로서 이는 만성화농성좌창을 가진 4歲의 女兒이었고 나머지 2例(66.7%)는 健康人採用身檢例에서의 FTA-ABS陰性으로서 BFP로 判定하였다. 이들 3가지 方法間의 同意率은 約 93.8%로서 FTA-ABS, TPHA 및 VDRL順으로 높은 特異度를 나타내었고 FTA-ABS, VDRL 및 TPHA順으로 높은 銳敏度를 나타내었다.
앞으로 TPHA와 FTA-ABS法을 VDRL이나 R-PR card法과 잘 組合하므로서 梅毒의 診斷에 正確을 期할 수 있다고 期待된다.

다국어 초록 (Multilingual Abstract)

Treponema pallidum hemagglutinatign (TPHA) and fluorescent treponemal antibody-absorption (FTA-ABS) tests were performed on 24 VDRL positive and 3 VDRL negative sera.
Twenty-one sera (87.5%) of 24 VDRL positive sera revealed "reactive" in TPHA and FTA-ABS, and these sera were related to clinical syphilis. Among the remainder 3 sera shown nonreactive TPHA, one serum disclosed reactive FTA-ABS which cases was having chronic pyogenic acne, and two sera revealed non-reactive FTA-ABS which cases were considered to be biological false positive (BFP) in healthy adult. Agreement between, TPHA and FTA were almost 100%.
The combined tests in syphilis were thought to be successful screening and confirmation.