연소성 골화 섬유종; 8 증례의 임상병리학적 분석 및 두개얼굴뼈에서 발생하는 섬유골병터와의 비교분석 = Juvenile Ossifying Fibroma: A Clinicopathologic Study of 8 Cases and Comparison with Craniofacial Fibro-osseousLesions

다국어 초록 (Multilingual Abstract)

Background : Juvenile ossifying fibroma (JOF) is defined as a variant of the ossifying fibroma,
and the latter includes juvenile trabecular ossifying fibroma (JTOF) and juvenile psammomatoid
ossifying fibroma (JPOF). JOF can be distinguished from other craniofacial fibroosseous
lesions by its tendency to recur and its clinical mimicry of malignant bone tumors,
but some clinical and histological features of JOF overlap with the other fibro-osseous lesions
as well. We aimed to identify the clinicopathologic definition of JOF. Methods : Forty-two cases
of fibro-osseous lesions were reviewed and they were classified into JOF, fibrous dysplasia
(FD) and ossifying fibroma (OF). Results : JTOF had long, slender and anastomosing trabeculae
of osteoid in a fibrocellular stroma, and JPOF had small ossicles resembling psammoma
bodies with a thick collagenous rim in the fibrous stroma, which are features that differ
from those of FD and OF. Radiologically, JOF and OF showed a well-defined lesion but FD
exhibited an ill-defined lesion. Clinically, the average age of the JOF patients was the youngest,
followed by OF and FD. For JOF, three cases had rapid growth and two others showed recurrences.
JOF mainly occurred in the paranasal sinuses, OF in the mandible and FD in any
craniofacial bone. Conclusion : We demonstrated the distinct characteristics of JOF and
these features may be helpful for the diagnosis and management of this malady.

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