한국인의 치주염 환자로부터 분리된 Staphylococcus aureus의 다양한 항생제 감수성 양상

다국어 초록 (Multilingual Abstract)

Saliva from the oral cavity was collected from 129 patients with periodontitis and 54 Staphylococcus aureus isolates were isolated from these samples. The S. aureus isolates were tested for their resistance patterns against 15 antibiotics using the disc diffusion method. The percentage of S. aureus isolates resistant to ampicillin was the highest (92.6%). In addition, the percentage of S. aureus isolates resistant to penicillin, oxacillin, cefotetan, cefepime and erythromycin was 90.7%, 11.1%, 11.1%, 9.3% and 5.6%, respectively. However, S. aureus isolates were susceptible to gentamycin, clindamycin, trimethoprim/sulfamethoxazole and vancomycin. 96.3% of S. aureus isolates were resistant to antibiotics. Among them, the percentage of two antibiotic-resistant S. aureus isolates was 74.1%, the percentage of one antibiotic-resistant S. aureus isolates was 5.6%, the percentage of three antibiotic-resistant S. aureus isolates was 3.7% and the percentage of S. aureus isolates resistant to more than 4 antibiotics was 13%. The most common multiple antimicrobial resistance pattern was AM-P. Furthermore, the percentage of methicillin-resistant S. aureus isolates was 11.1% and they were resistant to more than 3 antibiotics.

목차 (Table of Contents)

• Ⅰ. Introduction
• Ⅱ. Materials & Methods
• 1. Sampling
• 2. Isolation and genetic identification of S. aureus
• 3. Genomic DNA extraction and antimicrobialsusceptibility testing
• Ⅲ. Results
• 1. Isolation of S. aureus from periodontitis patients
• 2. Test for antibiotic susceptibility
• Ⅳ. Multiple Antimicrobial Resistance Patterns
• Ⅴ. Discussion
• Ⅵ. References