Creatine phosphokinase(CPK), lactate dehydrogenase(LDH), and lactate dehydrogenase isoenzymes were measured in the plasma of three elite marathon runners during marathon running(30km, 80%HRmax) and recovery.
Venous blood samples (antecubital vein) w...
Creatine phosphokinase(CPK), lactate dehydrogenase(LDH), and lactate dehydrogenase isoenzymes were measured in the plasma of three elite marathon runners during marathon running(30km, 80%HRmax) and recovery.
Venous blood samples (antecubital vein) were drawn before running, immediately 30, 60, 90, 120 min after running and in the -10, -30min of recovery.
Plasma total CPK and LDH activity was a continuously rise during running and recovery.
No significant rise was demomstrated in LDH H-specific type(LDH1+2), but a significant rise was shown in LDH M-specific type(LDH5).
These findings suggest that prolonged exercise stress(30km) of marathon runners was not found the cardiac muscle damage and enzyme efflux in cardiac muscle.
We conclude that increased levels of plasma enzyme activity contributed mainley to skeletal muscle, because of skeletal muscle is a much greater physiological stress than is a heart muscle.