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      Prognosis evaluation of a great dane dog with dilated cardiomyopathy

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      https://www.riss.kr/link?id=A105114093

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      다국어 초록 (Multilingual Abstract)

      A five-year-old, male, Great Dane weighing 107 kg was presented with anorexia, abdominal distension, and dyspnea for 5 days. Physical examination, blood works, radiography, electrocardiography (ECG), and echocardiography were performed. Based on sever...

      A five-year-old, male, Great Dane weighing 107 kg was presented with anorexia, abdominal distension, and dyspnea for 5 days. Physical examination, blood works, radiography, electrocardiography (ECG), and echocardiography were performed. Based on severely low fractional shortening (FS) and marked four chamber enlargement in echocardiography, continuous atrial fibrillation and occasional ventricular premature complex (VPC) on ECG, the dog was diagnosed as dilated cardiomyopathy (DCM) concurrent with congestive heart failure. Pleural effusion and ascites were modified transudate. In accordance with DCM scoring system recommended by European Society of Veterinary Cardiology (ESVC), DCM score was 13/15 in this case. Concentrations of cTnI and NT-pro-BNP were 1.0 ng/mL and 693 pmol/L, respectively. Since the former and the latter were remarkably high values, it was certain that the patient had grave prognosis. Intensive care was performed for the dog and the clinical signs as well as the radiographic abnormalities were resolved. However, when he presented serious dyspnea again at 25 days post therapy, the dog was dead. In case of canine DCM, the scoring system for the diagnosis and cardiac biomarkers including NT-pro-BNP and cTnI could be useful to advise owners on the status and prognosis of their dog with DCM.

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      참고문헌 (Reference)

      1 Fox PR, "Utility of plasma N-terminal pro-brain natriuretic peptide (NT-proBNP) to distinguish between congestive heart failure and non-cardiac causes of acute dyspnea in cats" 11 : S51-S61, 2009

      2 Boswood A, "The diagnostic accuracy of different natriuretic peptides in the investigation of canine cardiac disease" 49 : 26-32, 2008

      3 Sisson DD, "Textbook of veterinary internal medicine 5th edition Philadelphia" WB Saunders 874-895, 2000

      4 Tidholm A, "Survival in dogs with dilated cardiomyopathy and congestive heart failure treated with digoxin, furosemide and propranolol: A retrospective study of 62 dogs" 8 : 41-47, 2006

      5 Calvert CA, "Signalment, Survival, and Prognostic Factors in Doberman Pinschers With End‐Stage Cardiomyopathy" 11 : 323-326, 1997

      6 Kittleson MD, "Results of the Multicenter Spaniel Trial(MUST) : Taurine‐and Carnitine‐Responsive Dilated Cardiomyopathy in American Cocker Spaniels With Decreased Plasma Taurine Concentration" 11 : 204-211, 1997

      7 Calvert CA, "Results of ambulatory electrocardiography in overtly healthy Doberman Pinschers with equivocal echocardiographic evidence of dilated cardiomyopathy" 219 : 782-784, 2001

      8 Oyama MA, "Prospective screening for occult cardiomyopathy in dogs by measurement of plasma atrial natriuretic peptide, B-type natriuretic peptide, and cardiac troponin-I concentrations" 68 : 42-47, 2007

      9 Dukes-McEwan J, "Proposed guidelines for the diagnosis of canine idiopathic dilated cardiomyopathy" 5 : 7-19, 2003

      10 Borgarelli M, "Prognostic indicators for dogs with dilated cardiomyopathy" 20 : 104-110, 2006

      1 Fox PR, "Utility of plasma N-terminal pro-brain natriuretic peptide (NT-proBNP) to distinguish between congestive heart failure and non-cardiac causes of acute dyspnea in cats" 11 : S51-S61, 2009

      2 Boswood A, "The diagnostic accuracy of different natriuretic peptides in the investigation of canine cardiac disease" 49 : 26-32, 2008

      3 Sisson DD, "Textbook of veterinary internal medicine 5th edition Philadelphia" WB Saunders 874-895, 2000

      4 Tidholm A, "Survival in dogs with dilated cardiomyopathy and congestive heart failure treated with digoxin, furosemide and propranolol: A retrospective study of 62 dogs" 8 : 41-47, 2006

      5 Calvert CA, "Signalment, Survival, and Prognostic Factors in Doberman Pinschers With End‐Stage Cardiomyopathy" 11 : 323-326, 1997

      6 Kittleson MD, "Results of the Multicenter Spaniel Trial(MUST) : Taurine‐and Carnitine‐Responsive Dilated Cardiomyopathy in American Cocker Spaniels With Decreased Plasma Taurine Concentration" 11 : 204-211, 1997

      7 Calvert CA, "Results of ambulatory electrocardiography in overtly healthy Doberman Pinschers with equivocal echocardiographic evidence of dilated cardiomyopathy" 219 : 782-784, 2001

      8 Oyama MA, "Prospective screening for occult cardiomyopathy in dogs by measurement of plasma atrial natriuretic peptide, B-type natriuretic peptide, and cardiac troponin-I concentrations" 68 : 42-47, 2007

      9 Dukes-McEwan J, "Proposed guidelines for the diagnosis of canine idiopathic dilated cardiomyopathy" 5 : 7-19, 2003

      10 Borgarelli M, "Prognostic indicators for dogs with dilated cardiomyopathy" 20 : 104-110, 2006

      11 Wess G, "Prevalence of dilated cardiomyopathy in Doberman Pinschers in various age groups" 24 : 533-538, 2010

      12 Tarnow I, "Predictive value of natriuretic peptides in dogs with mitral valve disease" 180 : 195-201, 2009

      13 O'Sullivan ML, "Plasma Big Endothelin‐1, Atrial Natriuretic Peptide, Aldosterone, and Norepinephrine Concentrations in Normal Doberman Pinschers and Doberman Pinschers with Dilated Cardiomyopathy" 21 : 92-99, 2007

      14 Noszczyk-Nowak A, "NT-pro-BNP and troponin I as predictors of mortality in dogs with heart failure" 14 : 551-556, 2011

      15 Koch J, "M‐mode Echocardiographic Diagnosis of Dilated Cardiomyopathy in Giant Breed Dogs" 43 : 297-304, 1996

      16 Keene B, "Myocardial L-carnitine deficiency in a family of dogs with dilated cardiomyopathy" 198 : 647-650, 1991

      17 Schultheiss H, "Immunological analysis of auto-antibodies against the adenine nucleotide translocator in dilated cardiomyopathy" 17 : 603-617, 1985

      18 Monnet E, "Idiopathic dilated cardiomyopathy in dogs : survival and prognostic indicators" 9 : 12-17, 1995

      19 Wynne J, "Heart disease: a textbook of cardiovascular medicine" WB Saunders 1751-1806, 2001

      20 Wess G, "Evaluation of N-terminal pro-B-type natriuretic peptide as a diagnostic marker of various stages of cardiomyopathy in Doberman Pinschers" 72 : 642-649, 2011

      21 Sandusky GE, "Congestive cardiomyopathy in a dog associated with pregnancy" 74 : 60-64, 1984

      22 Oyama MA, "Clinical utility of serum N-terminal pro-B-type natriuretic peptide concentration for identifying cardiac disease in dogs and assessing disease severity" 232 : 1496-1503, 2008

      23 Oyama MA, "Clinical usefulness of an assay for measurement of circulating N-terminal pro-B-type natriuretic peptide concentration in dogs and cats with heart disease" 243 : 71-82, 2013

      24 Meurs KM, "Clinical features of dilated cardiomyopathy in Great Danes and results of a pedigree analysis : 17 cases(1990-2000)" 218 : 729-732, 2001

      25 Sleeper, MM, "Cardiac troponin I in the normal dog and cat" 15 : 501-503, 2001

      26 Fonfara S, "Cardiac troponin I as a marker for severity and prognosis of cardiac disease in dogs" 184 : 334-339, 2010

      27 Oyama MA, "Cardiac Troponin‐I Concentration in Dogs with Cardiac Disease" 18 : 831-839, 2004

      28 Tidholm A, "Canine idiopathic dilated cardiomyopathy. Part I: aetiology, clinical characteristics, epidemiology and pathology" 162 : 92-107, 2001

      29 Martin M, "Canine dilated cardiomyopathy : a retrospective study of signalment, presentation and clinical findings in 369 cases" 50 : 23-29, 2009

      30 Martin M, "Canine dilated cardiomyopathy : a retrospective study of prognostic findings in 367 clinical cases" 51 : 428-436, 2010

      31 Limas C, "Autoantibodies against beta-adrenoceptors in human idiopathic dilated cardiomyopathy" 64 : 97-, 1989

      32 Menaut P, "Atrial fibrillation in dogs with and without structural or functional cardiac disease : a retrospective study of 109 cases" 7 : 75-83, 2005

      33 Olson TM, "Actin mutations in dilated cardiomyopathy, a heritable form of heart failure" 280 : 750-752, 1998

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      기준연도 WOS-KCI 통합IF(2년) KCIF(2년) KCIF(3년)
      2016 0.2 0.2 0.22
      KCIF(4년) KCIF(5년) 중심성지수(3년) 즉시성지수
      0.23 0.24 0.315 0
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