소득 수준에 따른 골다공증 및 골감소증의 발생 = The Occurrence of Osteoporosis and Osteopenia between Two Groups with Different Socioeconomic Conditions

다국어 초록 (Multilingual Abstract)

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다국어 초록 (Multilingual Abstract)

Objectives: Osteoporosis is the term used for diseases of diverse etiology that cause a reduction in the mass of bone per unit volume. Several risk factors of osteoporosis have been identified. Osteoporotic subjects frequently have lower bone peak mass, earlier menopause, lower average body weight, less exercise, high incidence of smoking, excessive alcohol consumption and lower dietary calcium intake. Thus we evaluated the occurrence of osteoposis and osteopenia between two groups with different socioeconomic conditions. And we also checked the rate of remodeling of bone in two groups by one of the biochemical marker-type I collagen(prolagen C), Methods: Dual energy X-ray absorptiometry and Type I collagen were measured in 314 subjects with dissimiliar socioeconomic backgrounds. Results: 1) The occurrence of osteoporosis and osteopenia increased according to increasing age. Earlier and more occurrence of osteoporosis and osteopenia were noticed in the lower socioeconomic subjects than the middle and high socioeconomic subjects. 2) Type I collagen(Prolagen-C) showed 80.1±20.3ng/ml in the normal controls and significantly increased in the osteoporotic subjects as 125.5±60.8ng/ml. In the osteoporotic patients, type I collagen was increased significantly in the middle and high socioeconomic subjects than the lower socioeconomic subjects. '1'his group showed 90.3±15.5ng/ ml and that group showed 155.6±69.9ng/ml, Conclusion : It is suggested that osteoporosis and osteopenia can occur more and earlier in the lower socioeconomic subjects than the others. And those people experience more difficulties in the remodeling of bone than these