비염증성 만성골반통증후군에서 요로면역증강제, 유로박솜의 역할 = The Application of Uro-vaxom , Urinary Tract Immunostimulator in the Treatment of Chronic Pelvic Pain Syndrome

다국어 초록 (Multilingual Abstract)

Purpose: There are a variety of techniques for treating chronic prostatitis. Regardless of the presence of infections, antibiotics were arbitrarily prescribed for 4-12 weeks, but there seemed to be ongoing debate of their effectiveness and side effects. Uro-vaxomⓇ is known as an effective treatment for urinary tract infection due to its initiation the urothelial immune system activity. This study was performed to investigate for the possibility of Uro-vaxomⓇ as a drug for use in non-inflammatory chronic prostatitis.
Materials and Methods: 95 patients, diagnosed as chronic pelvic pain syndrome(CPPS)(National Institutes of Health(NIH)-category IIIB), were divided into three groups: group A, 35 patients were given levofloxacin 100mg TID and Uro-vaxomⓇ 60mg OD for the first 4 weeks, followed by only Uro-vaxomⓇ 60mg OD for the next 8 weeks; group B, 30 patients were given only Uro-vaxomⓇ 60mg OD before breakfast for 12 weeks; group C, the patients were treated with levofloxacin 100mg TID for 4 weeks. All the patients were reevaluated 4 weeks and 12 weeks later.
Results: The initial diagnostic stati, the NIH-Chronic Prostatitis Symptom Index(CPSI) were 25.1±2.7, 24.4±3.2 and 24.7±2.2 for groups A, B and C, respectively. In groups A and B, the NIH-CPSI after 12 weeks were 13.5±2.3 and 13.9±2.7, respectively, and showed noticeable improvements(p＜0.05). In group C, the NIH-CPSI was 15.7±3.4, which was less improved compared to groups A and B (p＞0.05). No patients experienced any adverse symptoms due to Uro- vaxomⓇ intake.
Conclusions: Uro-vaxomⓇ could be appointed as an alternative method for the treatment of chronic prostatitis

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