한국성인의 비만과 복부비만이 헤모글로빈에 미치는 영향 = Effect of General obesity and Abdominal obesity on Hemoglobin in Korean Adult

국문 초록 (Abstract)

본 연구의 목적은 성인의 체질량지수(BMI)와 허리둘레(WC)가 헤모글로빈(Hb)에 미치는 영향을 확인하는 것이다. 국민건강영양조사 제6기 3차년도(2015)자료를 이차분석 하였고 19세 이상의 5621명을 대상으로 하였다. 서술적 통계, t-test, ANOVA 및 Scheffe's test, Pearson correlation coefficient과 다변량 로지스틱 회귀분석을 적용하였다(SPSS WIN 25.0). 결과는, 첫째, BMI에 따라 Hb은 비만에서 가장 높았다(F=97.862, p<0.001). 둘째, WC에 따라 Hb은, 남성 WC≥90cm(t=4.909, p<0.001), 여성 WC≥85cm(t=5.088, p<0.001)에서 높았다. 셋째, Hb은 BMI(r=0.188, p<0.001) 및 WC(r=0.298, p<0.001)와 양의 상관관계를 나타내었다. 넷째, 남성에서 비만은 고헤모글로빈혈증이 2.30배(p<0.001), WC≥90cm은 1.81배(p<0.001)증가하였다. 여성에서 과체중은 1.99배(p=0.002), 비만은 5.66배(p<0.001), WC≥85cm은 4.27배(p<0.001) 고헤모글로빈혈증이 증가하였다. 본 연구를 바탕으로 비만예방 및 관리프로그램에 운동, 식이, 교육과 특히 복부비만해소를 위한 운동중재가 포함되어야 한다.

다국어 초록 (Multilingual Abstract)

The purpose of this study was to investigate the effect of body mass index(BMI) and waist circumference(WC) on hemoglobin(Hb) in Korean Adult. This study analyzed the data of 2015, The Sixth KNHANES. Data were analyzed using descriptive statistics, t-test, ANOVA and Scheffe's test, Pearson correlation coefficient and multivariate logistic regression analysis(SPSS 25.0). The major findings, The subject's Hb In BMI, obese was the highest(F=97.862, p<0.001). The Hb In WC, WC≥90cm was higher for male(t=4.909, p<0.001), and WC≥85cm was higher for female(t=5.088, p<0.001). Hb has a significant positive correlated with BMI(r=0.188, p<0.001), WC(r=0.298, p<0.001). In male, Hyperhemoglobinemia was 2.30 times(p<0.001) higher in obese and 1.81 times(p<0.001) higher in WC≥90cm. In female, Hyperhemoglobinemia was 1.99 times(p=0.002) higher in overweight, 5.66 times(p<0.001) higher in obese, and 4.27 times(p<0.001) higher in WC≥85cm. In conclusion, adult obesity prevention and management programs should include exercises, diets, and education, and exercise interventions specifically for eliminating abdominal obesity.

참고문헌 (Reference)

1 김종혁, "자전거 운동이 비만 중년여성의 염증관련인자 및 성장호르몬에 미치는 영향" 한국융합학회 9 (9): 449-456, 2018

2 조윤경, "대학생의 체성분분석과 혈구산정검사의 관계연구" 대한임상검사과학회 48 (48): 269-274, 2016

3 유승기, "과체중 및 비만 환자에서 좌심실 기능의 조기 변화: 티슈 도플러 심초음파를 이용한 분석" 대한심장학회 38 (38): 270-275, 2008

4 김종혁, "고령여성의 공복감 인지수준과 비만변인의 관계" 한국체육학회 54 (54): 475-483, 2015

5 M. A. Farhangi, "White blood cell count in women: relation to inflammatory biomarkers, haematological profiles, visceral adiposity, and other cardiovascular risk factors" 31 (31): 58-64, 2013

6 S D Hsieh, "Waist-to-height ratio, a simple and practical index for assessing central fat distribution and metabolic risk in Japanese men and women" Springer Science and Business Media LLC 27 (27): 610-616, 2003

7 Keiichi Odagiri, "Waist to Height Ratio Is an Independent Predictor for the Incidence of Chronic Kidney Disease" Public Library of Science (PLoS) 9 (9): e88873-, 2014

8 S. Zhu, "Waist circumference and obesity-associated risk factors among whites in the third National Health and Nutrition Examination Survey : clinical action thresholds" 76 (76): 743-749, 2002

9 K. W. Sim, "The relationship body mass index and morbidity in Korea" 10 (10): 147-155, 2001

10 World Health Organization Western Pacific Region, "The Asia-pacific perspective: Redefining obesity and its Treatment" WHO Western Pacific Region 2000

11 S. R. C. Mahtabuddin, "Study of Association of Sagittal Abdominal Diameter with Glycosylated Hemoglobin[HbA1c] in assessment of Risk of Type-II Diabetes Mellitus" 8 (8): 103-107, 2017

12 J. Vuong, "Reference intervals of complete blood count constituents are highly correlated to waist circumference: should obese patients have their own "normal values?" 89 (89): 671-677, 2014

13 World Health Organization, "Reducing Risks Promoting Healthy Life, World Health Report" 2002

14 C. W. Choi, "Prevalence and characteristics of anemia in the elderly : cross-sectional study of three urban Korean population samples" 77 (77): 26-30, 2004

15 D. Haslam, "Obesity" 366 (366): 1197-1209, 2005

16 R D Semba, "Low serum selenium is associated with anemia among older adults in the United States" Springer Science and Business Media LLC 63 (63): 93-99, 2009

17 R. Ungtrongchitr, "Leptin concentration in relation to body mass index(BMI)and hematological measurements in Thai obese and overweight subjects" 31 (31): 787-794, 2000

18 E. H. Al-Hashem, "Is it necessary to consider obesity when constructing norms for hemoglobin or when screening for anemia using hemoglobin levels?" 28 (28): 41-45, 2007

19 Florence Neymotin, "Iron and Obesity in Females in the United States" Wiley 19 (19): 191-199, 2010

20 Bum Ju Lee, "Identification of Hemoglobin Levels Based on Anthropometric Indices in Elderly Koreans" Public Library of Science (PLoS) 11 (11): e0165622-, 2016

21 Abdelmageed Elmugabil, "High level of hemoglobin, white blood cells and obesity among Sudanese women in early pregnancy: a cross-sectional study" Future Science Ltd 3 (3): FSO182-, 2017

22 A. M. Crabb, "Hemoglobin levels in normal-weight and obese patients during pregnancy" 57 (57): 105-108, 2012

23 M. Cesari, "Hemoglobin levels and skeletal muscle : results from the In chianti study" 59 (59): 249-254, 2004

24 R. K. Shrivastava, "Haemoglobin estimation by Non Cyandie-SLS Method" 6 (6): 394-395, 2017

25 O Pinhas-Hamiel, "Greater prevalence of iron deficiency in overweight and obese children and adolescents" Springer Science and Business Media LLC 27 (27): 416-418, 2003

26 American Medical Association, "Expert Panel on Detection, Evaluation, and treatment of high blood cholesterol in adults. Execute summary of the third report of the national cholesterol education program(NCEP)" 285 (285): 2486-2496, 2002

27 신경아, "Difference of The Cardiac Structure and Function Depending on Obesity Level of Healthy Adults" 대한의생명과학회 17 (17): 141-149, 2011

28 Scott M. Grundy, "Diagnosis and Management of the Metabolic Syndrome" Ovid Technologies (Wolters Kluwer Health) 112 (112): 2735-2752, 2005

29 S. Y. Lee, "Cut-off point of waist circumference for defining abdominal obesity in the Korean population" 15 (15): 1-9, 2006

30 Gerd Assmann, "Cardiovascular risk assessment in metabolic syndrome: view from PROCAM" Elsevier BV 33 (33): 377-392, 2004

31 박성규, "CBC 검사에서 혈구수치 이상에 대한 해석과 이해" 대한내과학회 78 (78): 531-539, 2010

32 Katarzyna Kordas, "Being Overweight or Obese Is Associated with Lower Prevalence of Anemia among Colombian Women of Reproductive Age" Oxford University Press (OUP) 143 (143): 175-181, 2013

33 S A Winther, "Association of anemia with the risk of cardiovascular adverse events in overweight/obese patients" Springer Science and Business Media LLC 38 (38): 432-437, 2014

34 Yu Qin, "Anemia in relation to body mass index and waist circumference among chinese women" Springer Science and Business Media LLC 12 (12): 1-3, 2013

35 Ryuichi Kawamoto, "A Slightly Low Hemoglobin Level Is Beneficially Associated with Arterial Stiffness in Japanese Community-Dwelling Women" Informa UK Limited 34 (34): 92-98, 2012