Design and Synthesis of Novel Antidiabetic Agents

다국어 초록 (Multilingual Abstract)

The synthesis and structure-activity relationships of a novel series of substituted quercetins that activates peroxisome proliferator-activated receptor gamma (PPARγ) are reported. The PPARγ agonistic activity of the most potent compound in this series is comparable to that of the thiazolidinedione-based antidiabetic drugs currently in clinical use.

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