폐쇄수면무호흡증과 심혈관 질환 관련성 연구 = Association Between Obstructive Sleep Apnea and Cardiovascular Diseases

다국어 초록 (Multilingual Abstract)

Background: Obstructive sleep apnea (OSA) contributes to the development of cardiovascular diseases. The aim of this
study is to analyze the association between OSA and cardiovascular diseases in adult.
Methods: We recruited 718 consecutive subjects (611 male, 44.8±12.7 years old) diagnosed as OSA based on overnight
polysomnography. The prevalence of hypertension, diabetes mellitus, myocardial infarction and stroke was defined and
compared with that in general adult population (the Third Korea National Health and Nutritional Examination Survey,
KNHANES III 2005). Correlation between the prevalence and OSA severity was analyzed after adjusting age, sex, body
mass index, smoking, and alcohol consumption.
Results: Prevalence of vascular diseases was higher in OSA than general population. Prevalence of hypertension was
39.0% (13.0% from KNHANES Ⅲ), diabetes 8.2% (5.2%), myocardial infarction 3.0% (0.6%) and stroke 7.2% (1.6%).
Apnea-hypopnea index as the marker of OSA severity significantly correlated with hypertension (p=0.01).
Conclusions: Cardiovascular diseases were more prevalent in OSA. Prevalence of hypertension increased proportionally
to OSA severity.

다국어 초록 (Multilingual Abstract)

Background: Obstructive sleep apnea (OSA) contributes to the development of cardiovascular diseases. The aim of this
study is to analyze the association between OSA and cardiovascular diseases in adult.
Methods: We recruited 718 consecutive subjects (611 male, 44.8±12.7 years old) diagnosed as OSA based on overnight
polysomnography. The prevalence of hypertension, diabetes mellitus, myocardial infarction and stroke was defined and
compared with that in general adult population (the Third Korea National Health and Nutritional Examination Survey,
KNHANES III 2005). Correlation between the prevalence and OSA severity was analyzed after adjusting age, sex, body
mass index, smoking, and alcohol consumption.
Results: Prevalence of vascular diseases was higher in OSA than general population. Prevalence of hypertension was
39.0% (13.0% from KNHANES Ⅲ), diabetes 8.2% (5.2%), myocardial infarction 3.0% (0.6%) and stroke 7.2% (1.6%).
Apnea-hypopnea index as the marker of OSA severity significantly correlated with hypertension (p=0.01).
Conclusions: Cardiovascular diseases were more prevalent in OSA. Prevalence of hypertension increased proportionally
to OSA severity.

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