A Simple GUI-based Sequencing Format Conversion Tool for the Three NGS Platforms

Rhie, A-Rang,Yang, San-Duk,Lee, Kyung-Eun,Thong, Chin Ting,Park, Hyun-Seok Korea Genome Organization 2010 Genomics & informatics Vol.8 No.2

To allow for a quick conversion of the proprietary sequence data from various sequencing platforms, sequence format conversion toolkits are required that can be easily integrated into workflow systems. In this respect, a format conversion tool, as well as quality conversion tool would be the minimum requirements to integrate reads from different platforms. We have developed the Pyrus NGS Sequencing Format Converter, a simple software toolkit which allows to convert three kinds of Next Generation Sequencing reads, into commonly used fasta or fastq formats. The converter modules are all implemented, uniformly, in Java GUI modules that can be integrated in software applications for displaying the data content in the same format.

Tendenz der deutschen Literatur : Die Neue Rechte 독일 우익작가들을 중심으로

Rhie, Sang Uk,A. Piederstorfer 한국독일어문학회 1998 독일어문학 Vol.7 No.-

독일이 동서독간의 이질감을 그대로 지닌체 예기치 않았던 통일을 맞게되자 외적인 통일 못지 않게 내적 정서적 통일문제가 중요시되면서 많은 연구 결과가 발표되었다.이들의 문제는 구동서독인들간의 문제와 더불어 외국인 문제 세대간의 갈등 문제들로서 급기야는 이들의 문제가 독일의 과거사를 거부하고 모든 전통을 거부했던 60년대 말의 급진 좌익세력에 대한 비판의식으로까지 이어지게 되었다. 이들의 비판에 앞장선 사람들은 Botho Strauß, Hans Magnus Enzensberg, Tankred Dorst, Peter Handke 등과 같은 보수 우익 작가들이었다.이들이 표방한 이데올로기는 과거 미국내에서 일어났던 인종차별 내지 소수민족간의 갈등 속에서 국민적 화합을 도출하려했던 새로운 문화 즉, "복수 문화주의"(Multikulturalismus)에서 비롯된 것이며 거슬러 올라가서 독일 낭만주의 문학의 "세계화주의"(Universalismus)에서 유래한 것이다. 이들의 이데올로기는 계몽주의자들과는 달리 언어,종족,풍속,민족정신,종교등에 자리한 문화적 종교적 국가적 통일성을 찾는 것이었다. 이는 독일내의 당면한 갈등 등에서 생겨난 정신적 공허감을 충족해 줘야 한다는 정신에서 일어난 변화인 것이다. 이와같은 변화의 물결은 1989년 독일에서 통독의 물결이 일어나기 시작하자 독일 역사에 대한 책임규명을 부르짖었던 전후세대와도 청산하려했으며 새로 발생한 개인주의적 "자유 서방인"(Freie Westen)에 대한 비판과 더불어 극단적인 감성주의적 물질주의자들의 세력을 저항하려 했다. 이와같은 움직임이 현재 독일 작가들에 의해서 활발해졌던 것이다. Botho Strauß의 수필집 "염소 노래"(Bocksgesang)는 독일의 과거사를 거부하고 모든 전통을 거부했던 60년대말의 급진적 좌익세력에 대해 비판을 가했을 뿐만 아니라, 자기고착화에 빠지거나 환상적인 유토피아에 빠진 경솔한 값싼 향락주의자들을 공격하고 있으며,공허한 대중매체에 편승하고 있는자들을 비판하며 사이비 계몽자들과 자기소외에 빠진자들에게도 비판의 화살을 돌렸다. Strauß는 또한 오디세이의 예화를 인용한 그의 드라마 "이타카"(Ithaka)에서도 이기주의자 물질만능주의자 향락주의자 등을 추방하고 이들의 정신적 지주가 될 옛 독일의 정신적 질서를 회복해야 한다고 주장했다. 이와같은 주장은 Peter Handke에 있어서도 비슷했다. 그 역시 옛 독일의 신화적 배경에서 불굴의 정신을 회복해야 한다고 했으며 심지어는 일찍이 유고슬라비아의 전쟁에서도 물질주의적인 서구인을 비판하고 옛독일의 자연상태를 찬양하면서 전쟁에서 학살을 감행했던 세리비아인 까지도 찬양했었다. 이와같은 일련의 독일정신의 복고주의를 부르짖는 신 우익작가들의 운동에 현재 Martin Walser, Hans Magnus Enzensberger 등과 같은 많은 독일작가들이 참여하고 있다. 이들은 현재 독일이 구 서독인과 동독인 사이의 이념적 갈등만이 문제가 아니라 민족간 계층간 세대간의 이질화로 인한 갈등 등으로 혼란에 빠지게 되자 우려의 목소리를 높이고 있다.

天龍山 第21石窟과 唐代碑銘의 硏究

Rhie, Marylin M. 동국대학교 박물관 1980 佛敎美術 Vol.5 No.-

Some Geometric Properties of the Weak<SUP>*</SUP>-integral

Rhie, Gil-Seob,Park, Hi-Kyo 충청수학회 1990 충청수학회지 Vol.3 No.1

We prove that if a $weak^*$-measurable function f defined on a finite measure space into a dual Banach space is separable-like, then for every measurable set E, the $weak^*$ core of f over E is the $weak^*$ convex closed hull of the $weak^*$ essential range of f over E.

Civilianization of the Military under Kim's Rule : Performance and Prospects

Rhie, June Hyoung the Center for International Studies, Inha Univers 1995 Pacific Focus Vol.10 No.1

A Comparison of the Dietary Habit and Nutrient Intakes of Korean Farmers according to Different Family Patterns and Farming Types

Rhie, Seoung-Gyo,Park, Yaungja Korean Society of Community Nutrition 1998 대한지역사회영양학회지 Vol.3 No.5

The purpose of this study was to compare the dietary habit and nutrient intakes of Korean farmers according to their different family patterns and farming types. Food and nutrient intakes were obtained by food frequency method. The subjects(male 35%, female 65% : mean age, $48{\pm}11 years)$ were compared 46% of nuclear family, 59% of 3-4 person of family size ; 50% of middle-scale farming ; 54% of rice farming. Sixteen percent were over 60 years old group. In aspects of dietary habit, farmers of medium size farming and 10-20 years of farming experience frequently skipped meals. But their appetite was better than small farm famers. Dinner irregularity was more frequent in their group of 3-4 person families. The numbers of food intake were significantly different according to family pattern. Nuclear family groups consumed more kinds of foods. The mean energy intake was 2000Kcal/day, with PFC ratio of 19 : 16 : 65. The energy and nutrient intakes showed the same tendency as the food variety. Intakes of calcium and iron were lower than the Korean RDA. Families with over 5 people consumed higher amounts of protein and minerals. Intakes of thiamin, niacin, and vitamin E were better in large families and large-scale farming groups. As compared with the PMS ratio, the level of monounsaturated fatty acids as higher than saturated FA. The lipid intake was also better in large families and large-scale farming. The results suggest that dietary habit and nutrient intakes were different by family pattern and farming types.

ON THE COMPLETENESS OF FUZZY NORMED LINEAR SPACES

RHIE, GIL SEOB,CHOI, BYUNG MUN,KIM, DONG SIK 대전대학교 이과대학 기초과학연구소 1997 自然科學 Vol.- No.-

The notions of the fuzzy a-Cauchy sequence and fuzzy completences are given. Also some of the related properties of fuzzy normed linear space are studied.

Foreign Corrupt Practices Act of 1977 And Independent Auditor's Responsibilities

Rhie, Yun J. 충남대학교 경상대학부설 경영경제연구소 1980 경영논집 Vol.2 No.1

Investigation of the Stress Distributions in a Transversely Isotropic Medium Containing a Spheroidal Cavity

Rhie Yoon Bock,Chun Chong Keun 한국전산구조공학회 1997 한국전산구조공학회논문집 Vol.10 No.1

This study investigates the stress distribution in a transversely isotropic medium containing a spheroidal cavity where the medium is under uniaxial tension in z;:iirection in one case and pure shear in the plane of isotropy in another case. The technical approach used in this study combines exact analytical and numerical methods. The exact analytical method is based upon three potential funct.ions taken in terms of the Legendre associated functions of the first and second kind. The numerical method is based upon the finite difference approach. Numerical results concerning the two loading conditions with fi ve anisotropic materials are presented.

Genomic Copy Number Variations Characterize the Prognosis of Both P16-Positive and P16-Negative Oropharyngeal Squamous Cell Carcinoma After Curative Resection

Rhie, Arang,Park, Weon Seo,Choi, Moon Kyung,Kim, Ji-Hyun,Ryu, Junsun,Ryu, Chang Hwan,Kim, Jong-Il,Jung, Yuh-Seog Williams & Wilkins Co 2015 Medicine Vol.94 No.50

ABSTRACT: Recently increasing high-risk HPV+ OSCC exhibits unique clinical and molecular characteristics compared to HPV-unrelated (HPV−) counterpart. Genomic copy number variations (CNVs), unique in HPV+ OSCCs, and their role for the prognosis prediction remains poorly studied. Here, we analyzed the distinct genomic copy number variations (CNVs) in human papillomavirus-related (HPV+) oropharyngeal squamous cell carcinoma (OSCC) and their role as a prognosticator after curative resection.For 58 consecutive, Korean OSCC patients that underwent surgery-based treatment with median 10 years of follow-up, HPV-related markers, and genome-wide CNV analysis were analyzed. Clinical associations between the CNV profile and survival analyses were followed.p16 expression predicted the overall survival (OS) (hazard ratio [HR] = 0.27, confidence interval [CI]: 0.39–0.80, P = 0.0006) better than HPV L1 PCR (HR = 0.83, CI: 0.66–1.29, P = 0.64), smoking, or other variables. Although the overall number of CNVs was not significantly different, 30 loci showed unique CNV patterns between the p16 and p16− groups. A region containing PRDM2 was amplified only in the p16 group, whereas EGFR and 11q13.3 showed increased amplification in p16− counterpart. Loss of a locus containing FGF18 led to a worse, but gain of region including CDK10 and RAD18 led to better overall survival (OS) in all OSCC patients. Meanwhile, subgroup analysis of p16 OSCC revealed that amplification of regions harboring HRAS and loss of locus bearing KDR led to better OS.p16 OSCC exhibit distinct CNV patterns compared with p16− counterpart. Specific patterns of CNVs predict better survival, especially in p16 OSCC. This might allow better insights of the outcome after curative resection for HPV+ and HPV− OSCC.