수소동위원소 저장용기 고온 안전성 해석

김광락,이민수,백승우,이성호,안도희,임성팔,정홍석 한국공업화학회 2003 응용화학 Vol.7 No.1

The immobilized hydrogen a titanium hydride could be used In a stainless steel vessel for the long-term storage of hydrogen isotopes. In order to predict the safety concerns of storage vessel at elevate temperature, a comprehensive mathematical model has been developed for diffusion analysis of hydrogen isotopes in the stainless steel vessel. Numerical results showed that significant amount of hydrogen isotopes could be released by permeation through the vesscl wall of 7mm thick at the 800℃ of hypothetical fire accident condition. A rapid permeation of tritium gives steady state permeation is achieved in approximately 5 hours at this temperaturc.

수소동위원소 운반용기 단열 해석

김광락,이민수,백승우,이성호,안도희,임성팔,정흥석 한국공업화학회 2003 응용화학 Vol.7 No.2

The immobilized hydrogen as a titanium hydride could be used in a stainless steel vessel for the long-term storage of hydrogen isotopes. The design analysis of a hydrogen isotope transport container with capacity of 0.5 MCi tritium was carried out to confirm the performance of the safely requirement. In order to verify that the radioactive transport container complies with the requirements for the B(U) type container stipulated in the MOST regulation of transport container, thermal analysis were made for normal condition and hypothetical accident conditions during transport. Thermal analysis with the Heating-7 code under conditions of 38℃ for 7 days and 800℃ for 30 minutes showed that the container complied with the requirement for B(U) type transport container.

타이타늄 수소화물의 수소동위원소 분석

김광락,백승우,이민수,이성호,안도희,임성팔,정홍석 한국공업화학회 2002 응용화학 Vol.6 No.2

In the hydrogen isotope facility and the fiel cycle of the fision reactor, an effective means for analyzing hydrogen isotopes and decay product(helium) of tritium is very importat from the viewpoint of system operation and control. Chromatographic separation of the hydrogen isotopes mixture from titanium hydride was carried out by gas chromatograph at-196℃ for quantitative analytical purpose.Neon and partially deactivated alumina were employed as the carrier gas and the fixed column, respectively. The chromatogram with complete separation was observed in order ofH_2, HD and D_2 by the thermal conductivity detector. In addition, fairly good separation conditions were obtained in a shorter retention time without any appearance of nuclear spin isomers for the practical applications of the hydrogen isotope separation and analysis.

국외 먹는 물 자외선 소독 법규

염철민,김도겸,정광열,유양수,조창현 대한상하수도학회 2003 상하수도학회지 Vol.17 No.6

Effects of electroacupuncture on clod allodynia in a rat model of neuropathic pain : Mediation by spinal adrenergic and serotonergic receptors

Kim, Sun-Kwang,Park, Jung-Hyuk,Bae, Sang-JIn,Kim, JI-Hoon,Hwang, Byung-Gil,Min, Byung-Il,Park, Doing Suk,Na, Heung-Sik EAST-WEST MEDICAL RESEARCH INSTITUTE KYUNG HEE UNI 2005 東西醫學硏究所 論文集 Vol.2005 No.-

The present study was performed to examine the effects of electroacupuncture (EA) on cold allodynia and its mechanisms related to the spinal adrenergic and serotonergic systems in a rat model of neuropathic pain. For the neuropathic surgery, the right superior caudal trunk was resected at the level between S1 and S2 spinal nerves innervating the tail. Two weeks after the nerve injury. EA simulation (2 or 100 Hz) was delivered to Zusanli (ST36) for 30 min. The behavioral signs of cold allodynia were evaluated by the tail immersion test{i.c., immersing the tail in cole water (4℃) and measuring the latency to an abrupt tail movement} before and after the stimulation. And then, we examined the effects of intrathecal injection of prazosin (α₁-adrenoceptor antagonist, 30 ㎍), yohimbine (α₂-adrenoceptor antagonist, 30 ㎍), NAN-190 (5HT_(1A) antagonist, 15 ㎍), ketanserin (5-HT_(2A) antagonist, 30 ㎍), and MDL-72222 (5-HT_(3) antagonist, 12 ㎍) on the action of EA simulation. Although both 2 Hz and 100 Hz EA significantly relieved the cold allodynia signs, 2 Hz EA induced more robust effects than 100 Hz EA. In addition, intrathecal injection of yohimbine, NAN-190, and MDL-72222, but not prazosin and ketanserin, significantly blocked the relieving effects of 2 Hz EA on cold allodynia. These results suggest that low-frequency (2 Hz) EA is more suitable for the treatment of cold allodynia than high-frequency (100 Hz) EA. and spinal α₂-adrenergic, 5-HT_(3), but not α₁-adrenergic and 5-HT_(2A), receptors play important roles in mediating the relieving effects of 2 Hz EA on cold allodynia in neuropathic rats.

효율적 영역 기반 부호화를 위한 인간 시각 특성에 기반한 계층적 영상 분할

송근원,정광민,도경훈 東西大學校 1998 동서논문집 Vol.4 No.-

본 논문에서는 주관적 화질 및 객관적 화질을 유지하면서 영역 기반 초저속 부호화에서 병목 현상을 유발하는 과다한 윤곽선 정보를 효과적으로 줄일 수 있으며, 또한 각 계층에서의 전송 정보량를 조절할 수 있는 계층적 영상 분할 알고리즘을 제안한다. 제안한 알고리즘은 각 계층에서 수리 형태학에 기반한 계층적 영상 분할과 인간 시각 시스템(HVS)특성을 고려한 영역 병합으로 구성된다. 계층적 영상 분할은 3계층으로 이루어져 있으며, 영상 분할 수 인간 시각이 구분할 수 없는 두 인접 영역을 병합한다. 이때 인간 시각 시스템 특성에 기반하여 병합 순서를 결정하는 병합 우선 순휘 함수(MPF)를 제한하여 영역 병합을 수행한다. 실험을 통하여 제안한 알고리즘은 기존의 알고리즘보다 PSNR은 평균 0.14dB 낮으나, 윤곽선 정보량은 30% 줄일 수 있었으며, 또한 각 계층에서 전송 정보량을 조절할 수 있는 적응성이 있는 영상 분할 구조임을 알 수 있었다. In this paper, a new hierarchical image segmentation algorithm based on human visual system(HVS) characteristic, which can efficiently reduce information quantity to be transmitted without the degradation of the subjective and objective image quality, and which is suitable for region-based very low bit coding because it can control information quantity to be transmitted, is proposed. It consists of image segmentation based on mathematical morphology and region merging considering HVS characteristic for the pairs of two adjacent regions at each level of the hierarchy. Image segmentation is composed of 3-level hierarchical structure and in the region merging structure of each level, we extract the pairs of two adjacent regions which human vision can't discriminate, and then merge them. Since the proposed region merging method selects two neighbor regions to be merged and performs region merging according to merging order based on HVS characteristics, it can efficiently improve bottleneck problem caused by excessive contour information at region-based very low bit rate coding. In experimental results, though the PSNR by the proposed algorithm is about 0.14dB lower than that of conventional method, the subjective image quality is almost the same and the contour information to be transmitted is reduced as much as 23.9% on the average.

3.5% NaCl 水溶液의 溫度變化가 SS41鋼의 腐蝕疲勞破壞에 미치는 影響

吳世旭,姜鎬珉,金廣泳,都映旼 東亞大學校 海洋資源硏究所 1988 硏究論文集 Vol.1 No.1

Corrosion fatigue test was performed under rotary bending in 3.5% NaCl aqueous solution having a temperature from 278°K to 318°K in order to investigate the effects of aqueous solution temperature on the corrosion fatigue fracture of SS41 steel. Fatigue life was remarkebly decreased with an increase in aqueous solution temperature. Fatigue life reductions for high stress level were somewhat smaller than those for low stress level, but S-N curves were nearly become parallel lines. Corrosion fatigue crack propagations were accelerated with an increase in aqueous solution temperature. The corrosion fatigue result at aqueous solution temperature of 303°K was showed about the same behaviour as those at 318°K in both S-N curve and da/dN-ΔK curve, which was considered as consequence of limiting diffusion current density(??). As aqueous solution temperature was increased, corrosion was gradually activated in view of fractured surface.

폴리머콘크리트 제조 방법

이민수,정홍석,임성팔,안도희,김광락,이성호,백승우,민병윤 한국공업화학회 2003 응용화학 Vol.7 No.2

In this paper, the foaming method of polymer concrete was studied. The pre-composition of polymer concrete consisted of unsaturated polyester as a binder material 15∼50wt%, sand 0∼80 wt%, filler 5-50 wt%, and foaming agent 0.1∼1.5 wt%. The pre-composition was heated at 100∼200℃ for 30∼120 minutes, which thermal treatment caused hardening of unsaturated polyester and cracking of foaming agent. The foamed polymer concrete showed low thermal transfer coefficent together with good mechanical properties.

제1형 당뇨병 환자에서 췌도세포 동종이식의 반복시행

양태영,정인경,서인아,오은영,조건영,오승훈,김성주,정재훈,민용기,이명식,이문규,김광원,도영수,주성욱 대한당뇨병학회 2002 Diabetes and Metabolism Journal Vol.24 No.4

연구배경:췌도세포 이식은 시술이 간편하고 안전하기 때문에 반복이식이 가능하여 그 동안 여러 센터에서 반복이식의 성공을 보고한 바 있다. 국내에서도 본 병원을 비롯하여 몇몇 센터에서 췌도세포 이식이 활발히 시도되고 있으나 사람에서의 동종이식 및 동종 이식의 반복시행은 보고된 바 없는 실정이다. 저자 등은 국내 최초로 췌도세포 동종이식을 시행하여, 혈청 C­펩타이드가 증가하고 인슐린 요구량이 감소하였으며, 혈당농도와 당화혈색소의 안정을 보였다. 그러나 이식 70일 후 다시 인슐린 요구량이 증가하고 C­펩타이드가 감소하여 췌도세포 이식을 다시 시행한 바 있다. 2차 이식 후 70여일이 지난 현재 다시 혈청 C­펩타이드가 증가하고, 인슐린 요구량이 더 감소되어 췌도세포 이식에서 반복 시행의 유용성을 보고하는 바이다. 방법:환자는 32세 남자로 17년전 당뇨병 진단 후 인슐린 치료 중이었으며, 3년전 부터는 만성신부전증으로 혈액툭석을 하고있었다. 1999년 12월 25일 신장이식을 하였고 3일 후 췌도이식을 하였으며, 두번째 이식은 70일 후 시행하였다. 췌도분리는 변형된 Recordi방법과 비연속성 자당 농도차(discontinuous density gradient)를 이용하였으며 분리한 췌도는 배양 후 환자의 신장기능이 정상화되고 미생물학 검사에서 음성을 확인한 후 경피경간으로 간문맥을 접근하여 16G 폴리 에틸렌 카테터를 이용하여 간실질에 이식하였다. 결과:1차 췌도이식시 순수분리전 췌도수는 210,000개, 순수분리후 획득한 췌도수는 90,000개, 순도 95%, 세포양 1.0mL 이었고, 2차 췌도이식시 순수분리전 췌도수는 420,000개, 순수분리후 획득한 췌도수는 370,000개, 순도 95%, 세포양 1.5mL 이었다. 1,2차 모두 간문맥을 통해 약 20분에 걸쳐 간실질에 주입하였다. 췌도이식전 인슐린요구량은 75∼75U/일, HbA1e 8∼10%, C­펩타이드 0.6ng/mL 였으며, 1차 췌도이식수 7일째 인슐린 요구량은 40U/일, C­펩타이드 1.5ng/mL, FPS 109mg/mL 였고, 40일 추적관찰 후 인슐린 요구량이 36U/일, C­펩타이드 1.8ng/mL, HbA1e 6.5∼7.0%로 안정되었다. 그러나 이식 50일째부터 인슐린 요구량이 50∼56U/일, C­펩타이드 0.6ng/mL, FPS 130∼200mg/dL로 혈당 조절이 불안정하여 다시 췌도이식을 시행하였다. 2차 이식후 50일이 경과한 현재, 인슐린 요구량은 26U/일, C­펩타이드 1.8ng/mL, FPS 90∼120mg/dL로 다시 안정되었다. 결론:췌도이식은 반복이식이 가능하며, 본 환자의 경우 인슐린요구량 감소, 혈당의 안정화 및 C­펩타이드가 상승하여 이식한 췌도의 기능을 확인할 수 있었고, 향후 스테로이드 등 면역억제가 유지 용량으로 감량되면 인슐린 요구량은 더 감소될 것으로 기대된다. Over the past 20 years, significant advances have been made in human islet transplantation. However, cases of prolonged insulin independence after islet allotransplantation have rarely been reported and over time, a slight, gradual decrease in insulin secretion appears to occur, as suggested by the lower C-peptide. Although preliminary clinical success achieved over the past few years has been considerably higher with whole pancreatic transplant than with isolated islet grafts, both approaches remain experimental. Islet grafts might gain, over time, increasing credibility and might eventually provide an easier alternative in terms of grafting procedures and patient management, as compared with the more "traumatizing" whole-pancreas transplantation. Also, using islet, re-transplantation is possible. But it is not known whether re-transplantation of islet could be suitable for those patients who lost grafted islet function. The aim of the present study was to investigate the benefits of re-transplantation of islet in previously simultaneous islets-kidney transplant (SIK) patient who have lost graft function. Methods : The recipient was a 32 year old male. First islet transplantation was underwent at December 25, 1999. However, the grafted islets lost function after 70 days. So we performed re-transplantation of islets. The isolation of islet was conducted sterilely on a laminarflow hood and isolated by a modified Recordimethod. The islet was injected slowly into the liver via a cannular placed in the potalvein for 20 minutes. Results : Transplanted islets were 90,000 IEq at first islet transplantation, 370,000 IEq at second islet transplantation. The insulin requirement was reduced from 75-85 to 35-40 U/day, the basal C-peptide level was 1.5 ng/mL at 7 days posttransplant Unfortunately, the grafted islets lost function after 70 days. After second transplantation, the insulin requirement was reduced to 26 U/day. Conclusions : Despite the continuous need for exogenous insulin therapy, islet transplantation can prevent wide glucose fluctuations, thus resulting in normalization of glycemic control and improvement in HbAlc, and also, show that islets can be successfully and safely re-transplanted intraportally in patients who have lost previously grafted islet function (J Kor Diabetes Asso 457~466, 2000).

Destruction of waste insulating oil containing PCBs at high temperature

( Min-kwang Suk ),( Gang-woo Lee ),( Jae-jeong Lee ),( Min-chul Kim ),( Yang-do Kim ),( Jong-hyeon Jung ),( Kyung-seun Yoo ),( Byung-hyun Shon ) 한국폐기물자원순환학회 2023 I-CIPEC Vol.2012 No.0