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      • 김삿갓의 자아 찾기, 웃음과 울음

        김준형 ( Kim Joon-hyeong ) 동방비교연구회 (구 한국동방문학비교연구회) 2016 동방문학비교연구 Vol.6 No.-

        김립은 `시`를 통해 자신의 존재 이유를 찾았다. 그의 시는 때로는 비유적으로, 때로는 직설적으로 세상에 대해 말한다. 욕설과 조롱의 시. 그 때문에 그는 학자들에게 비판을 받기도 했다. 그러나 우리가 주목해야 점은 욕설과 조롱 자체가 아니다. 오히려 그 이면에 담긴 김립의 사유가 더 중요하다. 노골적인 웃음 뒤에 감춰진 서글픈 자기 연민. 이 글에서 주목한 키워드다. 김립의 방랑은 개인적 분노에서 출발한다. 시간이 지나면서 그 분노는 사회로 향했다. 사회적 모순에 대한 분노가 크지만, 그는 아무 것도 할 수 없다. 그런 자신에 대한 부끄러움도 커졌다. 그의 시에 등장하는 사회에 대한 공격, 민중에 대한 애정, 자아 성찰은 이런 배경에서 만들어졌다. 특히 그의 시를 지배하는 웃음은 그 이면에 주목할 필요가 있다. 한바탕 웃고 넘어가면 그만인 작품 뒤에 숨겨진 통곡. 그것은 탈출구조차 찾지 못한 김립 시의 실체이기 때문이다. 그의 시가 울분의 시대를 살았던 식민지 지식인들 사이에서 널리 애송되었다는 점도 그와 맥을 같이 한다. The Joseon Dynasty poet Kim Lib (金笠) found his raison d`etre through poetry. Popularly known as “Kim Sat-gat the Wandering Minstrel,” Kim Lib, or Kim Byeong-yeon (金炳淵, 1807~ 1863) as his real name, speaks of the world sometimes metaphorically or sometimes bluntly. Because he wrote poems of profanity and mockery, he was often criticized by scholars. But, what should be noted as important is not profanity or mockery per se but the poet`s personal reason behind his works. The keyword is sad self-pity hidden behind obvious laughter. Kim Lib`s wandering started from personal rage. As time passed by, the rage was directed towards society. He was angry against social contradiction but he could not do anything. His sense of shame toward himself grew larger. His attack against society, affection for people and self-examination appearing his poems were made from such a background. Laughter in particular that dominates Kim`s poems should be noted in this regard. Behind the poems inviting simple bursts of laughter are wails of pain. That is the true nature of Kim Lib who could not find his way out.

      • KCI등재

        Tetrameric β를 이용한 고초균 포자에서의 미생물 표면 발현 모체 선별

        김준형,반재구,김병기,Kim, June-Hyung,Pan, Jae-Gu,Kim, Byung-Gee 한국생물공학회 2011 KSBB Journal Vol.26 No.3

        Using tetrameric ${\beta}$-galactosidase as a model protein, anchoring motives were screened in Bacillus subtilis spore display system. Eleven spore coat proteins were selected considering their expression levels and the location in the spore coat layer. After chromosomal single-copy homologous integration in the amyE site of Bacillus subtilis chromosome, cotE and cotG were chosen as possible spore surface anchoring motives with their higher whole cell ${\beta}$-galactosidase activity. PAGE and Wester blot of extracted fraction of outer layer of purified spore, which express CotE-LacZ or CotG-LacZ fusion verified the existence of exact size of fusion protein and its location in outer coat layer of purified spore. ${\beta}$-galactosidase activity of spore with CotE-LacZ or CotG-LacZ fusion reached its highest value around 16~20 h of culture time in terms of whole cell and purified spore. After intensive spore purification with lysozyme treatment and renografin treatment, spore of BJH135, which expresses CotE-LacZ, retained only 1~2% of its whole cell ${\beta}$-galactosidase activity. Whereas spore of BJH136, which has cotG-lacZ cassette in the chromosome, retained 10~15% of its whole cell ${\beta}$-galactosidase activity, proving minor perturbation of CotG-LacZ, when incorporated in the spore coat layer of Bacillus subtilis compared to CotE-LacZ. Usage of Bacillus subtilis WB700, of which 7 proteases are knocked-out and thereby resulting in 99.7% decrease in protease activity of the host, did not prevent the proteolytic degradation of spore surface expressed CotG-LacZ fusion protein.

      • KCI등재

        외측대퇴회선동맥 상행가지의 천공지피판을 이용한 대전자부 욕창의 재건

        김준형,어수락,조상헌,Kim, Jun-Hyung,Eo, Su-Rak,Cho, Sang-Hun 대한성형외과학회 2010 Archives of Plastic Surgery Vol.37 No.5

        Purpose: Trochanteric pressure sores management has been improved through the development of musculocutaneous flaps. But it has many drawbacks such as donor site morbidity and functional muscle sacrifice. With the introduction of perforator flap, it is possible to use in every location where musculocutaneous perforators are present. We have reconstructed trochanteric pressure sores using perforator-based flaps from the ascending branch of lateral circumflex femoral artery. Methods: Between May of 2006 and April of 2008, we performed six cases of perforator-based flap from the ascending branch of lateral circumflex femoral artery for the coverage of trochanteric pressure sores. For identifying perforators, a line was drawn from the anterior superior iliac spine to the superolateral border of the patella as the vertical axis, from the pubis to the trochanteric prominence as the horizontal axis. In the lateral aspect of the intersection of these two axes, various flap were designed according to its defects. The flap was raised in the subcutaneous plane above the fascia and the pedicle was traced by doppler and identified. The pedicle was meticulously dissected not to injure the periadventitial tissues and transposed to the defect. The donor site was closed primarily. Results: The mean age of patients was 56.2 years. Four male and two female patients were studied. Five patients were paraplegic. The mean defect size was $6{\times}4\;cm$. The largest flap dimension was $14{\times}7\;cm$. Donor sites were closed primarily without any complications. All flaps survived completely without necrosis, hematoma or infection. There were no recurrence during the follow-up period. Conclusion: Trochanteric pressure sores using perforator-based flap from the ascending branch of lateral circumflex femoral artery can be performed safely and it would be a reliable option for coverage of trochanteric pressure sores with minimal donor site morbidity.

      • KCI등재

        한국인 전립선비대증 환자에서 두타스테리드의 안전성 평가를 위한 시판 후 조사

        김준형,배지영,오신영,이일섭,Kim, Joon-Hyung,Bae, Ji-Young,Oh, Shin-Young,Lee, Yil-Seob 대한임상약리학회 2012 臨床藥理學會誌 Vol.20 No.1

        Background: Dutasteride is an inhibitor of both types I and II 5 alpha-reductase and was approved in Korea in April 2004. This post-marketing surveillance was to assess the safety of dutasteride in Korean patients with benign prostate hyperplasia in real life and to elucidate the risk factors related adverse events. Methods: From December 2004 to January 2010, 3,977 patients were enrolled by 184 urologists. According to post-marketing surveillance regulation, patients were enrolled consecutively. Patients administered dutasteride at least once were included in safety assessment. The incidences of any adverse events and serious adverse events were evaluated. Multiple logistic regression method was used to identify risk factors related to adverse events. Results: The safety assessment included 3,870 patients with the mean age of 67.3 years. The incidence of adverse events was 3.8%. The most frequent adverse event was impotence (75 cases, 1.9%), libido decrease (49 cases, 1.3%), ejaculation disorder (30 cases, 0.8%), and gynecomastia (5 cases, 0.1%). The incidence of unexpected adverse events was 0.5% and cerebral infarction, lung cancer, pulmonary embolism, and diarrhea were reported as serious adverse events. Conclusion: In this survey, impotence was the most frequently reported adverse events. Dutasteride was well tolerated in Korean patients with benign prostate hyperplasia. These results updated the safety information and would provide important additional information for prescribers.

      • KCI등재

        AC-PDP용 인산염 결정화 유리의 유전적 특성에 관한 연구

        김준형,연석주,Kim, Joon-Hyung,Yon, Seog-Joo 한국결정성장학회 2007 韓國結晶成長學會誌 Vol.17 No.3

        인산염계 유리를 사용하여 PDP 소자의 하판유전체 후막을 제작하였다. 유전체 후막의 제조는 soda-lime glass위에 silk screen printing 법을 사용하였다. 기판과 유전체후막의 열팽창계수를 맞추기 위하여 $TiO_2$와 $Al_2O_3$를 충진제로 사용하였다. 유전체의 결정화 거동은 DTA, XRD를 사용하였으며 광학적 열적 전기적인 특성을 알아보기 위하여 UV-spectrometer, Dilatometer, Impedance Analyser를 사용하였다. 실험결과 주 결정상은 메타인산아연과 피로인산아연으로 나타났다. $TiO_2$의 첨가로 인하여 반사율은 높아졌으나 상대적으로 유전상수는 높아졌다. 또한 $Al_2O_3$를 첨가한 경우 반사율은 크게 변화가 없었으나 유전상수 값은 낮아졌다. 또한 열팽창 계수는 약 $62{\times}10^{-7}/^{\circ}C$ 정도였다. Dielectric layer of phosphate glass for plasma display panel (PDP) device made by silk screen printing on soda-lime glass. For regulate thermal expansion coefficient (CTE) of between substrate glass and dielectric layer use addition of $Al_2O_3$ and $TiO_2$. The crystallization process of glass-ceramics for dielectric layer have been examined by DTA, XRD some of optical, electrical properties of the dielectric layer were evaluated by UV-spectrometer, dilatometer, impedance analyser. The principal crystalline phase was identified as zinc metaphosphate [$Zn(PO_3)_2$] and zinc pyrophosphate [$Zn_2P_2O_7$]. Reflectance and dielectric constance increased with the addition of $TiO_2$ filler, dielectric constant lower the out side reflectance unchanging of the adding of $Al_2O_3$ filler. Besides CTE was at about $62{\times}10^{-7}/^{\circ}C$.

      • KCI등재
      • SCOPUSKCI등재

        꽃며느리밥풀 Ethyl acetate 분획물의 예쁜 꼬마선충에 대한 항산화 효과

        김준형,박창범,박종현,권강무,황인현,마상용,오석흥,김대근,Kim, Jun Hyeong,Park, Chang Bum,Park, Jong Hyun,Kwon, Kang Mu,Hwang, In Hyun,Ma, Sang Yong,Oh, Suk-Heung,Kim, Dae Keun 한국생약학회 2022 생약학회지 Vol.53 No.2

        Caenorhabditis elegans model system was used to investigate the antioxidant activity of methanol extract of Melampyrum roseum (Scrophulariaceae). The ethyl acetate soluble fraction of the M. roseum methanol extract showed the best DPPH radical scavenging activity. The ethyl acetate fraction was measured for the activity of superoxide dismutase (SOD), catalase, and oxidative stress tolerance by using C. elegans along with reactive oxygen species (ROS) level. In addition, to confirm that the regulation of the stress response gene is responsible for the increased stress tolerance of C. elegans treated by the ethyl acetate fraction, SOD-3 expression was measured using a transgenic strain. As a result, the ethyl acetate fraction increased SOD and catalase activity, and decreased ROS accumulation in a dose-dependent manner. In addition, the ethyl acetate fraction-treated CF1553 worm showed higher SOD-3::GFP intensity than the control worm.

      • Adaptive Load Balancing based on Consistency

        김준형,오하령,이재문,Kim, Jun-Hyeong,O, Ha-Ryeong,Lee, Jae-Mun 한국정보처리학회 1995 정보처리논문지 Vol.2 No.3

        부하 평형은 과부하 사이트의 부하종 일부를 다른 사이트로 옮김으로써 분산 처리 시스템의 성능 개선을 꾀한다. 본 논문에서는 source-initiate와 server-initiate 방 식을 모두 지원하며 극단적인 예로서 m/m/1 대기행렬(부하 비평형)과 m/m/n 대기 행렬 (완전한 부하 평형)도 모델화 할 수 있는 부하 평형 방식을 제안하였다. 이 방식은 상 태 변수를 각 사이트에 복제하고 각 복사본의 일치성을 완화한다. 그리고 오래된 스케 줄러가 통신을 하지 않고도 부하 평형을 보장할 수 있는 충분조건을 요도하였다. 이 모델을 이용하면 부하 평형의 문제가 상태의 일관성을 유지하는 문제로 바뀌게 되며 기존의 비딩 알고리즘보다 통신량이 적어지게 된다. 이벤트 트레이싱 방법으로 모의 실험하였으며 2개의 극단적인 경우 및 비딩알고리즘과 비교하였다. 그 결과 평균 응답 시간과 통신량에 있어서 비딩알고리즘보다 각각 0-35%, 40-100%의 성능향상을 보였다. 마지막으로 각 시스템 피라미터의 영향을 분석하였다. Load balancing attempts to improve the performance of a distributed computing system by transferring some of the workload of a congested site to others. A load balancing scheme that supports both the source-initiated and the server- initiated load balancing is proposed in this paper. It can model both the m/m/1 queue(no load balancing) and the m/m/n queue(perfect load balancing) as the extreme State variables are replicated into every site, and copy consistency constraints are relaxed more weakly. We propose weak copy consistency constraints which correlate the outdated state information to that of the current state. We also derive sufficient conditions under which each scheduler can guarantee the load balancing without communication Using this model, the problem of load balancing is converted to that of maintaining the consistency of states and communication overhead becomes less than that of the bidding algorithm. The scheme is simulated by event tracing, compared to the two extreme cases and the bidding algorithm. The results show that the mean response time and the number of messages are reduced by 0-35% and 40-100% respectively, compared with the bidding algorithm. Finally the effects of some system parameters are described.

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