A new compound operation method of the numerical solutions And analytic solution of partial differential equation

Yu-Jie Ren,Yan-Juan Li,Fu-Gui Song,Hong-Qing Zhang 한국멀티미디어학회 2006 한국멀티미디어학회 국제학술대회 Vol.2006 No.-

In the paper, a new compound operation method of the numerical solutions and analytic solution (if exist) is proposed to constructing explicit solutions for nonlinear partial differential equations based on computation system MATLAB. The validity and reliability of the method is tested by its application to the Toda-Lattice equations in (2+1) dimensions. More new explicit solutions are found. The compound operation method can be also applied to other nonlinear partial differential equations.

A mechanization method on the mixed operation of the numerical solutions, analytic solution, and showing their figures simultaneously for differential equation

Yu-Jie Ren,Fu-Gui Song,Yan-Juan Li,Hong-Qing Zhang 한국멀티미디어학회 2006 한국멀티미디어학회 국제학술대회 Vol.2006 No.-

In the paper, a new mechanization method on the mixed operation of the numerical solutions, analytic solution (if exist), and showing their figures simultaneously for differential equation and their MATLAB programs are presented. With the aid of computer software MATLAB, Euler's method is chosen to illustrate the validity and advantages of the method. As a result, we can not only see the analytic solution, numerical solutions, and their errors but also observe how step size affects the error of the numerical solutions by a figure. The mechanization method can be also applied to other numerical method.

Research on Wormhole Attack Detection Algorithm in Space Information Networks

Yu Geng,Zhang jie,Zhang Yongfang,Ye ning,Ren Kaiya 보안공학연구지원센터 2016 International Journal of Security and Its Applicat Vol.10 No.5

Wormhole attack is a coordinated attack that launched by two or more malicious node. With a high quality private link malicious node, attracted traffic, attacked routing protocol, destroyed network topology, has a great threat to space information network. We propose a wormhole attack detection algorithm based on abnormal topology and time delay in space information network and the algorithm is mainly composed of two phases: finding abnormal topology and getting the malicious node. According to the number of nodes which are mutually non-one-hop neighbors in the normal network and the abnormal topology in backbone get the suspicious neighbors. To confirm the fake link, uses the round trip time to detect suspicious neighbors. Sends warning messages to isolate false neighbors or malicious nodes to ensure the security of the network. Using the network simulation software NS2 analyses the performance of the detection algorithm. The simulation results show that the proposed algorithm can detect wormhole also has high detection rate and a low false positive rate.

Rodent peri-implantitis models: a systematic review and meta-analysis of morphological changes

Ren Jie Jacob Chew,Jacinta Xiaotong Lu,Yu Fan Sim,Alvin Boon Keng Yeo 대한치주과학회 2022 Journal of Periodontal & Implant Science Vol.52 No.6

Purpose: Rodent models have emerged as an alternative to established larger animal models for peri-implantitis research. However, the construct validity of rodent models is controversial due to a lack of consensus regarding their histological, morphological, and biochemical characteristics. This systematic review sought to validate rodent models by characterizing their morphological changes, particularly marginal bone loss (MBL), a hallmark of peri-implantitis. Methods: This review was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. A literature search was performed electronically using MEDLINE (PubMed), and Embase, identifying pre-clinical studies reporting MBL after experimental peri-implantitis induction in rodents. Each study’s risk of bias was assessed using the Systematic Review Center for Laboratory animal Experimentation (SYRCLE) risk of bias tool. A meta-analysis was performed for the difference in MBL, comparing healthy implants to those with experimental peri-implantitis. Results: Of the 1,014 unique records retrieved, 23 studies that met the eligibility criteria were included. Peri-implantitis was induced using 4 methods: ligatures, lipopolysaccharide, microbial infection, and titanium particles. Studies presented high to unclear risks of bias. During the osseointegration phase, 11.6% and 6.4%-11.3% of implants inserted in mice and rats, respectively, had failed to osseointegrate. Twelve studies were included in the meta-analysis of the linear MBL measured using micro-computed tomography. Following experimental peri-implantitis, the MBL was estimated to be 0.25 mm (95% confidence interval [CI], 0.14–0.36 mm) in mice and 0.26 mm (95% CI, 0.19–0.34 mm) in rats. The resulting peri-implant MBL was circumferential, consisting of supra- and infrabony components. Conclusions: Experimental peri-implantitis in rodent models results in circumferential MBL, with morphology consistent with the clinical presentation of peri-implantitis. While rodent models are promising, there is still a need to further characterize their healing potentials, standardize experiment protocols, and improve the reporting of results and methodology.

Facile Self-Assembly of Fe3O4 Nanoparticles@WS2 Nanosheets: A Promising Candidate for Supercapacitor Electrode

Yu Dai,Xiao Wu,Dawei Sha,Ming Chen,Han Zou,Jie Ren,Jingjing Wang,Xuehua Yan 대한금속·재료학회 2016 ELECTRONIC MATERIALS LETTERS Vol.12 No.6

Graphene-like dichalcogenides with huge surface area and nanostructuredtransition metal oxides with extraordinarily high theoretical capacities could becomposited as promising electrode candidates for supercapacitors. In this work,monolayer and few-layers WS2 nanosheets were exfoliated by combination ofball-milling and sonication. A facile strategy for the hierarchical self-assembly ofFe3O4 nanoparticles (Fe3O4NPs) on WS2 nanosheets was developed to synthesizeFe3O4NPs@WS2 nanocomposites via hydrothermal method. Fe3O4NPs areuniformly dispersed on the WS2 nanosheets without aggregation. The particlesize of Fe3O4NPs is about 3 nm. The nanocomposite shows strong enhancementsof electrochemical behaviors. This self-assembly synthesis strategy may havegreat prospects for other 0D/2D nanocomposites in supercapacitors and otherenergy devices.

Rodent peri-implantitis models: a systematic review and meta-analysis of morphological changes

Ren Jie Jacob Chew,Jacinta Xiaotong Lu,Yu Fan Sim,Alvin Boon Keng Yeo Korean Academy of Periodontology 2022 Journal of Periodontal & Implant Science Vol.52 No.6

Purpose: Rodent models have emerged as an alternative to established larger animal models for peri-implantitis research. However, the construct validity of rodent models is controversial due to a lack of consensus regarding their histological, morphological, and biochemical characteristics. This systematic review sought to validate rodent models by characterizing their morphological changes, particularly marginal bone loss (MBL), a hallmark of peri-implantitis. Methods: This review was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. A literature search was performed electronically using MEDLINE (PubMed), and Embase, identifying pre-clinical studies reporting MBL after experimental peri-implantitis induction in rodents. Each study's risk of bias was assessed using the Systematic Review Center for Laboratory animal Experimentation (SYRCLE) risk of bias tool. A meta-analysis was performed for the difference in MBL, comparing healthy implants to those with experimental peri-implantitis. Results: Of the 1,014 unique records retrieved, 23 studies that met the eligibility criteria were included. Peri-implantitis was induced using 4 methods: ligatures, lipopolysaccharide, microbial infection, and titanium particles. Studies presented high to unclear risks of bias. During the osseointegration phase, 11.6% and 6.4%-11.3% of implants inserted in mice and rats, respectively, had failed to osseointegrate. Twelve studies were included in the meta-analysis of the linear MBL measured using micro-computed tomography. Following experimental peri-implantitis, the MBL was estimated to be 0.25 mm (95% confidence interval [CI], 0.14-0.36 mm) in mice and 0.26 mm (95% CI, 0.19-0.34 mm) in rats. The resulting peri-implant MBL was circumferential, consisting of supra- and infrabony components. Conclusions: Experimental peri-implantitis in rodent models results in circumferential MBL, with morphology consistent with the clinical presentation of peri-implantitis. While rodent models are promising, there is still a need to further characterize their healing potentials, standardize experiment protocols, and improve the reporting of results and methodology.

A national survey on how to improve traditional Chinese medicine learning internationally: Perceptions from both teachers and students

Zhu Yu-Hang,Yan Wu,Hao Zhang,Yanfei Zhao,Yule Ren,Wei Hu,Pan Li,Huiyi Wang,Ying Wang,Boda Zhang,Yujie Wang,Hongwen Yuan,Jiping Zhang,Wenqiang Li,Yufang Zhao,Jie Zhao,Yedong Shi,Yanye Shu,Xiao Zhang,Ya 한국한의학연구원 2022 Integrative Medicine Research Vol.11 No.4

Background With the increasing popularity of traditional Chinese medicine (TCM) by the global community, how to teach basic knowledge of TCM to international students and improve the teaching quality are important issues for teachers of TCM. The present study was to analyze the perceptions from both students and teachers on how to improve TCM learning internationally. Methods A cross-sectional national survey was conducted at 23 universities/colleges across China. A structured, self-reported on-line questionnaire was administered to 34 Chinese teachers who taught TCM course in English and to 1016 international undergraduates who were enrolled in the TCM course in China between 2017 and 2021. Results Thirty-three (97.1%) teachers and 900 (88.6%) undergraduates agreed Chinese culture should be fully integrated into TCM courses. All teachers and 944 (92.9%) undergraduates thought that TCM had important significance in the clinical practice. All teachers and 995 (97.9%) undergraduates agreed that modern research of TCM is valuable. Thirty-three (97.1%) teachers and 959 (94.4%) undergraduates thought comparing traditional medicine in different countries with TCM can help the students better understand TCM. Thirty-two (94.1%) teachers and 962 (94.7%) undergraduates agreed on the use of practical teaching method with case reports. From the perceptions of the undergraduates, the top three beneficial learning styles were practice (34.3%), teacher's lectures (32.5%), case studies (10.4%). The first choice of learning mode was attending to face-to-face teaching (82.3%). The top three interesting contents were acupuncture (75.5%), Chinese herbal medicine (63.8%), and massage (55.0%). Conclusion To improve TCM learning among international undergraduates majoring in conventional medicine, integration of Chinese culture into TCM course, comparison of traditional medicine in different countries with TCM, application of the teaching method with case reports, and emphasization of clinical practice as well as modern research on TCM should be fully considered.

Continuous DC-CIK Infusions Restore CD8⁺ Cellular Immunity, Physical Activity and Improve Clinical Efficacy in Advanced Cancer Patients Unresponsive to Conventional Treatments

Zhao, Yan-Jie,Jiang, Ni,Song, Qing-Kun,Wu, Jiang-Ping,Song, Yu-Guang,Zhang, Hong-Mei,Chen, Feng,Zhou, Lei,Wang, Xiao-Li,Zhou, Xin-Na,Yang, Hua-Bing,Ren, Jun,Lyerly, Herbert Kim Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.6

Background: There are few choices for treatment of advanced cancer patients who do not respond to or tolerate conventional anti-cancer treatments. Therefore this study aimed to deploy the benefits and clinical efficacy of continuous dendritic cell-cytokine induced killer cell infusions in such patients. Materials and Methods: A total of 381 infusions (from 67 advanced cases recruited) were included in this study. All patients underwent peripheral blood mononuclear cell apheresis for the following cellular therapy and dendritic cells-cytokine induced killer cells were expanded in vitro. Peripheral blood T lymphocyte subsets were quantified through flow cytometry to address the cellular immunity status. Clinical efficacy and physical activities were evaluated by RECIST criteria and Eastern Cooperative Oncology Group scores respectively. Logistic regression model was used to estimate the association between cellular infusions and clinical benefits. Results: An average of $5.7{\pm}2.94{\times}10^9$ induced cells were infused each time and patients were exposed to 6 infusions. Cellular immunity was improved in that cytotoxic $CD8^+CD28^+$ T lymphocytes were increased by 74% and suppressive $CD8^+CD28^-$ T lymphocytes were elevated by 16% (p<0.05). Continuous infusion of dendritic cells-cytokine induced killer cells was associated with improvement of both patient status and cellular immunity. A median of six infusions were capable of reducing risk of progression by 70% (95%CI 0.10-0.91). Every elevation of one ECOG score corresponded to a 3.90-fold higher progression risk (p<0.05) and 1% increase of $CD8^+CD28^-$ T cell proportion reflecting a 5% higher risk of progression (p<0.05). Conclusions: In advanced cancer patients, continuous dendritic cell-cytokine induced killer cell infusions are capable of recovering cellular immunity, improving patient status and quality of life in those who are unresponsive to conventional cancer treatment.

Intra-operative Rectal Washout with Saline Solution Can Effectively Prevent Anastomotic Recurrence: a Meta-analysis

Zhou, Can,Ren, Yu,Wang, Ke,Liu, Jie,He, Jian-Jun,Liu, Pei-Jun Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.12

Background and Objective: Rectal washout with saline solution may theoretically prevent anastomotic recurrence in patients with resectable rectal cancer, although exact clinical effects have not yet been determined. In order to derive a more precise estimation of the relationship, the present meta-analysis was performed. Method: Relevant studies were identified by a search of Medline, Embase and Google Website with no restrictions to September 1, 2013, and included in the systematic review and meta-analysis. Results: 5 trials (642 participants) were included to assess the association between rectal washout with saline solution and anastomotic recurrence. The rate of anastomotic recurrence (AR) was 6.23% (40/642), with the pooled OR derived from the five studies being 0.32 (95 % CI=0.15-0.70, P=0.004). The pooled OR derived from the TME and radical resection subgroups were 0.72 (95%CI=0.16-3.12, P=0.66) and 0.51 (95%CI=0.13-1.96, P=0.32), respectively. Conclusion: Results from this analysis show that intra-operative rectal washout with mere saline solution largely reduces the risk of anastomotic recurrences in patients with resectable rectal cancer.

Mangiferin loaded magnetic PCEC microspheres: preparation, characterization and antitumor activity studies in vitro

WenJing Xiao,Jun Hou,Jie Ma,BoTao Yu,JianDong Ren,WeiHua Jin,Juan Wu,DeZhi Zheng,KaiHua Fan 대한약학회 2021 Archives of Pharmacal Research Vol.44 No.8

Mangiferin is a promising effective chemopreventiveagent against various tumors. However, itsclinical use is limited by poor water solubility and lowbioavailability. In this article, mangiferin loaded magneticPCEC microspheres (MG-MS) were designed, characterizedand the antitumor activity of MG-MS was evaluatedin vitro. The magnetic nanoparticles (MNP) were synthesizedvia the high-temperature reaction of ironacetylacetonate in phenyl ether in the presence of oleic acidand oleylamine. Poly (ε-caprolactone)-poly (ethyleneglycol)-poly (ε-caprolactone) (PCL-PEG-PCL, PCEC)copolymers were formed by ring-opening copolymerizationof ε-CL initiated by PEG-diol using Sn(Oct)2 as acatalyst and MG-MS were prepared by solvent diffusionmethod. MNP, PCEC copolymer, and MG-MS werecharacterized by GPC, TEM, XRD, FT-IR, 1H-NMP andMalvern Laser Particle Sizer. Meanwhile, the antiproliferativeactivity in vitro and in vitro release behavior of thismicrospheres were studied in detail. The results indicatethat the obtained magnetic microspheres might have greatpotential as an effective carrier for mangiferin used incancer chemotherapy.