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Hirsutism may indicate tumor etiology of the ovary: a case report of leydig cell hyperplasia
( Gil Jae Jung ),( Hae Ryung Choi ),( Ye Jin Seon ),( So Ryeong Kim ),( Hwan Shin ),( Ji Hye Kim ),( Yun Dan Kang ),( Jin Wan Park ),( Jong Soo Kim ) 대한산부인과학회 2020 대한산부인과학회 학술대회 Vol.106 No.-
We report a case of a 59-year-old woman who complaint excessive beard. She had hypertension and obesity and had undergone a previous right salpingo-oopherectomy and total thyroidectomy. On physical examination, she had male-pattern balding and excessive beard, sternal and peri-areolar terminal hair growth. The clitoris was moderately enlarged. Only serum testosterone elevated 5.8 ng/ml which 193 times than normal. In CT and MRI scan, 7*3cm sized tumor was observed in endometrium with adenomyotic uterus and atrophic left ovary. She underwent total hysterectomy with left oophorectomy. Histopathological examination and immunohistochemistry verified the diagnosis of an leydig cell hyperplasia in left ovary. Serum testosterone normalized and the virilization progressively subsided over the following few months. This report underlined that careful research of patient history of virilization for diagnosis of androgen producing tumor after menopause.
( Ye-ri Ji ),( Yoo-sun Hong ),( Dongyeop Lee ),( Ji-heon Hong ),( Jae-ho Yu ),( Jin-seop Kim ),( Seong-gil Kim ) 대한물리치료학회 2021 대한물리치료학회지 Vol.33 No.6
Purpose: This study aims to measure the improvement of balanced ability and rapid response of 30 healthy adults by performing dynamic stretching, static stretching, and sargent jump. Methods: The sample 30 peoples without any musculoskeletal disease who volunteered to be the subject of the study. We measured all subjects on following metrics to evaluate the function and stability under the normal condition, with dynamic stretching (DS) group, static stretching (SS) group: vertical jump height and reaching distance Anterior, Posteromedial, Posterolateral and NO (Normal eye open), NC (Normal eye close), PO (Pillow with eye open), and PC (Pillow with close eye) were evaluated. All measures were analyzed using independent t-test and One-way repeated Anova. Results: There was a significant increase in SJH (Sargent jump) in both groups (p<0.05). In Y-balance test, there was a significant increase in both groups except for the ANT (Anterior) direction, and there was a significant increase only in the SS group in the ANT (Anterior) direction (p< 0.05). There was no significant difference between the DS group and the SS group (p >0.05). There was no significant improvement in ST (Stability Index) and WDI (Weight Distribution Index) in both groups (p>0.05). Conclusion: Both DS and SS showed significant improvement in SJH and Y-balance tests, which are dynamic functions, but had no significant effect on static balance ability.
Ye-Jong Park,Shin Hwang,Ki-Hun Kim,Young-Joo Lee,Chul-Soo Ahn,Deok-Bog Moon,Kwang-Min Park,Tae-Yong Ha,Gi-Won Song,Dong-Hwan Jung,Gil-Chun Park,Jae-Hun Lee,Sung-Gyu Lee 한국간담췌외과학회 2013 한국간담췌외과학회지 Vol.17 No.3
Backgrounds/Aims: Laparoscopic cholecystectomy (LC) has become a standard procedure for treatment of benign gallbladder diseases. There has been a small proportion of gallbladder cancer (GBC) which was incidentally found in the gallbladder specimen, and LC has been tried in some patients with faintly suspected GBC. This study intended to analyze the prognosis of patients with pT1b/T2 GBC who have undergone LC and the outcome of extended re-operation. Methods: After analyzing the institutional profiles of 500 GBC patients who have undergone surgical resection, we selected 64 patients who underwent LC initially from January 1996 to December 2008 and whose gallbladder pathology was confined to pT1b or pT2 lesions. Of them, 34 patients (53.1%) underwent extended reoperation. Their medical records were reviewed retrospectively. Results: In the LC only group (n=30), mean age of the 16 pT1 patients was 65.7±12.5 years and mean age of the 14 pT2 patients was 66.7±10.1 years. In the reoperation group (n=34), mean age of the 8 pT1b patients was 52.6±9.9 years and in 26 pT2 patients, mean age was 59.2±7.9 years. The reoperation group showed a younger patient age pattern than the LC only group (p=0.001). The types of reoperation were liver resection with lymph node (LN) dissection in 17, bile duct resection with LN dissection in 2, and hepatectomy and bile duct resection with LN dissection in 15. In the LC only group, the 5-year survival rate (5-YSR) was 70.3% in pT1b and 43.2% in pT2. In the reoperation group, 5-YSR was 62.5% in pT1b (n=8) and 59.5% in pT2 (n=26). A survival comparison between the two groups showed no significant survival gain in pT1 patients (p=0.69) and in pT2 patients (p=0.14). In our whole database analysis, 5-YSR of pT1bNx lesions was 70% after cholecystectomy and 78% after extended cholecystectomy. Lymph node metastasis was identified in 11% of pT1b lesions. For pT2N0 lesions, overall 5-YSR was 62% after R0 resection, showing no survival difference between primary extended surgery and LC-redo operation (p=0.45). Conclusions: The survival gain of reoperation was not evident in pT1b lesions. In contrast, some noticeable but not statistically significant survival difference was observed in pT2 lesions. Thus, reoperation for pT1b/T2 GBC following LC is indicated for individualized reasons, especially in patients with pT1b lesions. Old age was one of the important factors in deciding not to reoperate.