現代性和現代文學的審美意識問題

吳曉東 中國語文硏究會 1999 中國語文論叢 Vol.17 No.-

Effect of Trichostatin A on CNE2 Nasopharyngeal Carcinoma Cells - Genome-wide DNA Methylation Alteration

Yang, Xiao-Li,Zhang, Cheng-Dong,Wu, Hua-Yu,Wu, Yong-Hu,Zhang, Yue-Ning,Qin, Meng-Bin,Wu, Hua,Liu, Xiao-Chun,Lina, Xing,Lu, Shao-Ming Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.11

Trichostatin A (TSA) is a histone deacetylase (HDAC) inhibitor. We here investigated its effects on proliferation and apoptosis of the CNE2 carcinoma cell line, and attempted to establish genome-wide DNA methylation alteration due to differentially histone acetylation status. After cells were treated by TSA, the inhibitory rate of cell proliferation was examined with a CCK8 kit, and cell apoptosis was determined by flow cytometry. Compared to control, TSA inhibited CNE2 cell growth and induced apoptosis. Furthermore, TSA was found to induce genome-wide methylation alteration as assessed by genome-wide methylation array. Overall DNA methylation level of cells treated with TSA was higher than in controls. Function and pathway analysis revealed that many genes with methylation alteration were involved in key biological roles, such as apoptosis and cell proliferation. Three genes (DAP3, HSPB1 and CLDN) were independently confirmed by quantitative real-time PCR. Finally, we conclude that TSA inhibits CNE2 cell growth and induces apoptosis in vitro involving genome-wide DNA methylation alteration, so that it has promising application prospects in treatment of NPC in vivo. Although many unreported hypermethylated/hypomethylated genes should be further analyzed and validated, the pointers to new biomarkers and therapeutic strategies in the treatment of NPC should be stressed.

Stereo-digital image correlation in the behavior investigation of CFRP-steel composite members

Xiao-Yuan He,Yun-Tong Dai,Hai-Tao Wang,Tian-Yuan Ge,Gang Wu,Jian-Xiao Wan,Shuang-Yin Cao,Fu-Jun Yang 국제구조공학회 2017 Steel and Composite Structures, An International J Vol.23 No.6

The application of carbon fiber reinforced polymer (CFRP) in steel structures primarily includes two categories, i.e., the bond-critical application and the contact-critical application. Debonding failure and buckling failure are the main failure modes for these two applications. Conventional electrometric techniques may not provide precise results because of the limitations associated with single-point contact measurements. A nondestructive full-field measurement technique is a valuable alternative to conventional methods. In this study, the digital image correlation (DIC) technique was adopted to investigate the bond behavior and buckling behavior of CFRP-steel composite members. The CFRP-to-steel bonded joint and the CFRPstrengthened square hollow section (SHS) steel column were tested to verify the suitability of the DIC technique. The stereo- DIC technique was utilized to measure continuous deformation. The bond-slip relationship of the CFRP-to-steel interface was derived using the DIC data. Additionally, a multi-camera DIC system consisting of four stereo-DIC subsystems was proposed and applied to the compressive test of CFRP-strengthened SHS steel column. The precise buckling location and CFRP delamination of the CFRP-strengthened SHS steel column were identified. The experimental results confirm that the stereo-DIC technique can provide effective measurements for investigating the behaviors of CFRP-steel composite members.

Failure analysis of prestressed concrete containment vessels under internal pressure considering thermomechanical coupling

Wu Yu-Xiao,Fei Zi-Jian,Feng De-Cheng,Song Meng-Yan 한국원자력학회 2023 Nuclear Engineering and Technology Vol.55 No.12

After a loss of coolant accident (LOCA) in the prestressed concrete containment vessels (PCCVs) of nuclear power plants, the coupling of temperature and pressure can significantly affect the mechanical properties of the PCCVs. However, there is no consensus on how this coupling affects the failure mechanism of PCCVs. In this paper, a simplified finite element modeling method is proposed to study the effect of temperature and pressure coupling on PCCVs. The experiment results of a 1:4 scale PCCV model tested at Sandia National Laboratory (SNL) are compared with the results obtained from the proposed modeling approach. Seven working conditions are set up by varying the internal and external temperatures to investigate the failure mechanism of the PCCV model under the coupling effect of temperature and pressure. The results of this paper demonstrate that the finite element model established by the simplified finite element method proposed in this paper is highly consistent with the experimental results. Furthermore, the stress-displacement curve of the PCCV during loading can be divided into four stages, each of which corresponds to the damage to the concrete, steel liner, steel rebar, and prestressing tendon. Finally, the failure mechanism of the PCCV is significantly affected by temperature.

Effects of Cementitious Coating on Steel in Simulated Concrete Pore Solution

Wu, Xiao Lin(오효림),Kim, Sang Hyo(김상효),Ann, Ki Yong(안기용) 한국콘크리트학회 2010 한국콘크리트학회 학술대회 논문집 Vol.2010 No.5

Clinical Study on Fluvoxamine Combined with Oxycodone Prolonged-Release Tablets in Treating Patients with Moderate to Severe Cancer Pain

Xiao, Yang,Liu, Jun,Huang, Xin-En,Ca, Li-Hua,Ma, Yi-Min,Wei, Wei,Zhang, Rong-Xia,Huang, Xiao-Hong,Chang, Juan,Wu, Yi-Jia Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.23

Objective: To observe treatment effects and safety of fluvoxamine combined with oxycodone prolonged-release tablets in treating patients with moderate to severe cancer pain. Methods: Patients confirmed pathologically with cancer and complicated with moderate to severe pain, were divided into control and experimental groups. Oxycodone prolonged-release tablets, with or without fluvoxamine, were administrated to all study patients until pain relief. Degree of pain relief, dose of oxycodone prolonged-release tablets, side effects and quality of life were compared before and after treatment. Results: In total, 120 patients were recruited. No statistically significant difference was detected regarding age, gender, types of cancer, KPS between two groups of patients (P>0.05). Baseline pain score of patients with moderate pain in treatment and control group was $4.9{\pm}0.8$ and $5.1{\pm}0.8$, respectively; and decreased to $1.8{\pm}1.1$ and $1.2{\pm}1.1$ after treatment, respectively. Pain intensity was significantly reduced in the treatment group (P=0.028). Average daily consumption of oxycodone prolonged-release tablets was ($54.0{\pm}19.6$) mg and ($44.7{\pm}18.7$) mg respectively, which is lower in treatment grpup than in control group, but the difference was not statistically significant (P=0.065). Baseline pain score of patients with severe pain in treatment and control groups were $8.3{\pm}1.1$ and $8.3{\pm}1.1$, respectively; and pain intensity after treatment decreased to $2.9{\pm}1.0$ and $2.3{\pm}1.0$. Pain intensity was significantly reduced in the treatment group, with statistical significance (P=0.026). Average daily consumption of oxycodone prolonged-release tablets was ($132.0{\pm}42.2$) mg and ($110.7{\pm}33.9$) mg, respectively, which is lower in treatment group than in control group, and the difference was statistically significant (P=0.035). In terms of quality of life, patients in treatment group had better performance status, daily activity, mood, and sleep than that in control group (P < 0.05). Patients in two groups had similar side effects, eg., constipation, nausea/vomiting, lethargy, dizziness, itchy skin, dysuria, and ataxia. Lower incidence of nausea/vomiting, lethargy, was obtained from patients in treatment than in control group, while significant low constipation was observed in treatment than in control group (35.0% vs 49.2%, P=0.026). Conclusion: Fluvoxamine combined with oxycodone prolonged-release tablets could be more effective in treating patients with cancer pain, and could reduce the dosage of oxycodone prolonged-release tablets and thus be associated with lower side effects, and improved quality of life.

BTC-9500 : General Aspect of Developments

Xiao Fei Wu 대한전자공학회 1998 대한전자공학회 워크샵 Vol.1998 No.-

A Comparative Study of Chinese and Western Film Colors

Xiao-Hui Wu(우시아오훼이) 한국엔터테인먼트산업학회 2019 한국엔터테인먼트산업학회논문지 Vol.13 No.4

영화는 흑백영화부터 컬러영화로 접어들면서 스크린영상이 질적인 변화를 가져왔다. 영화 속의 색채는 물상의 객관적인 모습을 원한재현기능을 가지고 있을 뿐만 아니라 다른 주관적인 감정을 전달하는 기능도 가지고 있다. 색채 외에는 표현할 수 없는 예술적인 효과를 표현할 수 있고 스토리 자체가 전달하지 못하는 컨텐츠도 전달할 수 있다. 그러므로 영화색채는 영화언어의 중요한 구성요소가 되었다. 영화 속에 색채는 단화면색채, 신색채, 영화전체의 색채기조 및 줄거리에 따라 만드는 여러 가지 색채체인으로 스크린에서 나타났다. 영화예술 수법은 몽타주조법을 사용해서 화면 속에 색채도 몽타주형식이 형성되며 이것이 색채몽타주라고 부른다. 대중들이 색채에 주관적인 평가가 색채언어에 대한 받아들인 수준은 각 부분적인 색조사이에 상호작용에 의해 표현할 수 있다. 색채의 독특한 속성은 색채가 구조상태에 들어가야 하는 것을 결정하였다. 그래야 색채의 고유한 매력을 표현할 수 있다. 영화색채가 이런 ‘색채구조’의 층면에 들어가야 진정한 신미가치를 가질 수 있다. 본문은 동서양감독들의 색채사유와 동서양 영화색채에 담고 있는 문화의 차이 두 가지 측면을 통해 동서양영화 색채에 대해 비교적 연구를 하고자 한다. 서양감독들은 색채의 구조성을 강조하여 색조몽타주방식으로 인물의 감정을 표현하는 것을 중시하며 주관적 색채를 부여하는 특징을 구체적으로 드러낸다. 중국영화의 경우는 제5대 감독으로부터 영화색채언어의 새로운 장이 열리기 시작한다. 감정과 경치가 서로 융화하다가 ‘의상합일’의 영화 특징을 알렸다. The film enters the color film from black and white, and the screen image changes qualitatively. The color in the film not only has the reproduction function of the restoration object like the objective appearance, but also has the function of conveying different subjective emotions. It can express the color and can’t express it. The artistic effect conveys the information content that the story itself can’t convey, so the color of the film becomes an important part of the film language. The color in the film is presented on the screen in the form of single-screen color, scene color, full-color color tone, and various color chains designed according to different contradictions and conflicts. Because the film art and art means are assembled by montage, he colors in the picture also form a montage form. People call it "color montage". People"s subjective nature of color criticism and acceptance of color language also depend on various local tones. The accurate expression of the relationship, the unique attribute of color determines that the color must enter the structural state in order to express its unique charm. The color of the film only has the real aesthetic value when it enters the level of "color structure". This paper studies the color of Chinese and Western films from the differences between the color thinking of Chinese and Western film directors and the cultural implication of Chinese and Western film colors. The western film director emphasizes the structure of color and pays attention to the use of tonal montage to convey the characters. Emotions reflect the characteristics of a subjective color. Beginning with the "fifth-generation" director of Chinese film, the new journey of film color language has been opened. In the process of blending love and scenery, the film style of "image-in-one" has been achieved.

Patterns of Lymph Node Recurrence after Radical Surgery Impacting on Survival of Patients with pT1-3N0M0 Thoracic Esophageal Squamous Cell Carcinoma

Xiao-li Chen,,Tian-wu Chen,Zhi-jia Fang,Xiao-ming Zhang,Zhen-lin Li,Hang Li,Hong-jie Tang,Li Zhou,Dan Wang,Zishu Zhang 대한의학회 2014 Journal of Korean medical science Vol.29 No.2

The aim of this study was to investigate how patterns of lymph nodes recurrence after radical surgery impact on survival of patients with pT1-3N0M0 thoracic esophageal squamous cell carcinoma. One hundred eighty consecutive patients with thoracic esophageal squamous cell carcinoma underwent radical surgery, and the tumors were staged as pT1-3N0M0 by postoperative pathology. Lymph nodes recurrence was detected with computed tomography 3-120 months after the treatment. The patterns of lymph nodes recurrence including stations, fields and locations of recurrent lymph nodes, and impacts on patterns of survival were statistically analyzed. There was a decreasing trend of overall survival with increasing stations or fields of postoperative lymph nodes involved (all P<0.05). Univariate analysis showed that stations or fields of lymph nodes recurrence, and abdominal or cervical lymph nodes involved were prognostic factors for survival(all P<0.05). Cox analyses revealed that the field was an independent factor (P<0.05, odds ratio=2.73). Lymph nodes involved occurred predominantly in cervix and upper mediastinum (P<0.05). In conclusion, patterns of lymph node recurrence especially the fields of lymph nodes involved are significant prognostic factors for survival of patients with pT1-3N0M0 thoracic esophageal squamous cell carcinoma.

Letters to the Editor : Successful Treatment of Hailey-Hailey Disease with Aminolevulinic Acid Photodynamic Therapy

( Xiao Xiao Yan ),( Hong Qing Tian ),( Chang Liang Wang ),( Bao Qi Yang ),( Wei Zhi Wu ),( Fu Ren Zhang ) 대한피부과학회 2015 Annals of Dermatology Vol.27 No.3