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        Multiphysical Design and Optimization of High-Speed Permanent Magnet Synchronous Motor with Sinusoidal Segmented Permanent Magnet Structure

        Liu Chengcheng,Zhang Hongming,Wang Shaoheng,Wang Youhua,Lei Gang,Zhu Jianguo 대한전기학회 2024 Journal of Electrical Engineering & Technology Vol.19 No.3

        High speed permanent magnet synchronous motor (HSPMSM) is an important driving motor for electric vehicles. Compared with the electric motor operated under normal speed, it is critical to reduce the torque ripple, vibration, and noise of the HSPMSM. Furthermore, The air-gap fux density total harmonic distortion and electromotive force total harmonic distortion determine by torque performance and vibration noise. This article uses analytical methods to analyze the infuence of permanent magnet sinusoidal segmentation (PMS) on the electromagnetic performance of surface-mounted HSPMSM. The fnite element method is used to calculate the infuence of diferent permanent magnet segmentation numbers, diferent adjacent permanent magnet decreasing thickness, and diferent center PM width on the electromagnetic performance of permanent magnet sinusoidal segmented surface-mounted high-speed permanent magnet synchronous motor (M2). Comparing the efectiveness of PMS in surface-mounted HSPMSM and interior HSPMSM. Furthermore, the rotor dynamics analysis and vibration noise analysis on M2 are performed, and the infuence of PMS on the stress and vibration noise of both motors’ rotors is summarized. This article proposes a parameter preprocessing grouping multiphysical multi-objective high-dimensional multilevel optimization method. Taking M2 as an example, a global optimization design was carried out for the high-dimensional structural parameters brought by PMS, which improved the electromagnetic performance of M2 and reduced the vibration noise and rotor stress.

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        Chinese Society of Allergy Guidelines for Diagnosis and Treatment of Allergic Rhinitis

        Lei Cheng,Jianjun Chen,Qingling Fu,Shaoheng He,Huabin Li,Zheng Liu,Guolin Tan,Zezhang Tao,Dehui Wang,Weiping Wen,Rui Xu,Yu Xu,Qintai Yang,Chonghua Zhang,Gehua Zhang,Ruxin Zhang,Yuan Zhang,Bing Zhou,Do 대한천식알레르기학회 2018 Allergy, Asthma & Immunology Research Vol.10 No.4

        Allergic rhinitis (AR) is a global health problem that causes major illnesses and disabilities worldwide. Epidemiologic studies have demonstrated that the prevalence of AR has increased progressively over the last few decades in more developed countries and currently affects up to 40% of the population worldwide. Likewise, a rising trend of AR has also been observed over the last 2-3 decades in developing countries including China, with the prevalence of AR varying widely in these countries. A survey of self-reported AR over a 6-year period in the general Chinese adult population reported that the standardized prevalence of adult AR increased from 11.1% in 2005 to 17.6% in 2011. An increasing number of original articles and imporclinical trials on the epidemiology, pathophysiologic mechanisms, diagnosis, management and comorbidities of AR in Chinese subjects have been published in international peer-reviewed journals over the past 2 decades, and substantially added to our understanding of this disease as a global problem. Although guidelines for the diagnosis and treatment of AR in Chinese subjects have also been published, they have not been translated into English and therefore not generally accessible for reference to non-Chinese speaking international medical communities. Moreover, methods for the diagnosis and treatment of AR in China have not been standardized entirely and some patients are still treated according to regional preferences. Thus, the present guidelines have been developed by the Chinese Society of Allergy to be accessible to both national and international medical communities involved in the management of AR patients. These guidelines have been prepared in line with existing international guidelines to provide evidence-based recommendations for the diagnosis and management of AR in China.

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        Altered Expression of Substance P and NK1R in CCR3+ and CD123+HLA-DR− Basophils Under Airway Allergic Conditions

        Geng Shiyang,Xie Hua,Chen Liping,Chen Dong,Lu Sijing,Zhao Nan,Yang Ruiming,Wang Zhao,He Shaoheng,Zhang Huiyun 대한천식알레르기학회 2022 Allergy, Asthma & Immunology Research Vol.14 No.6

        Purpose: To explore expression of SP and NK1R in basophils of allergic asthma (AA), allergic rhinitis (AR) and AR combined with AA (ARA), and influence of allergens and immunoglobulin E (IgE) mediated mechanisms on SP and NK1R expression. Methods: Expression of SP and NK1R was detected by flow cytometry, NK1R mRNA expression was detected by real time quantitative polymerase chain reaction (qPCR), and mouse AR and AA models were employed for in vivo study. Results: SP+ and NK1R+ cells increased in CCR3+ and CD123+HLA-DR− granulocytes of AA. PPE elevated proportions of SP+ cells in CCR3+ and CD123+HLA-DR− granulocytes, whereas ASWE and HDME augmented SP+ cells in CD123+HLA-DR− granulocytes of AR and ARA patients. ASWE, HDME and PPE increased proportions of NK1R+ cells in CCR3+ PBMC and CD123+HLA-DR− granulocytes of AR patients. OVA, Der p1, IL-33, IL-37, IgE and SP enhanced NK1R expression on KU812 cells. NK1R expressing basophils were increased in blood of OVA sensitized and challenged AR and AA mice. FcεRI-KO AA mice seemed to have less NK1R+ basophils than WT AA mice in their blood. Conclusion: CCR3+ and CD123+HLA-DR− cells are likely involved in AA and AR via SP and NK1R. IgE-related mechanism may participate in upregulation of NK1R expression.

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