Acupuncture treatment of a male patient suffering from long-term schizophrenia and sleep disorders

Bosch, Peggy,Staudte, Heike,Yeo, Sujung,Lee, Sook-Hyun,Lim, Sabina,van den Noort, Maurits Elsevier 2017 Journal of traditional Chinese medicine Vol.37 No.6

<P><B>Abstract</B></P> <P><B>Objective</B></P> <P>To investigate the effectiveness of acupuncture in the treatment of chronic schizophrenia and co-morbid sleep disorders.</P> <P><B>Methods</B></P> <P>A 42-year-old German male outpatient, suffering from long-term schizophrenia and sleep disorders, entered the study. Acupuncture was used as a non-pharmacological intervention. In addition to his ongoing Western Medicine (pharmacological) treatment, the patient received 12 weekly (non-standardized) acupuncture treatments in the clinic. The Traditional Chinese Medicine (TCM) diagnosis, the psychological assessment and the actiwatch data were compared before and after the acupuncture treatment.</P> <P><B>Results</B></P> <P>The TCM diagnosis revealed a Liver Fire pattern before the acupuncture treatment, which was still present, although to a lesser degree, after the treatment. The psychological assessment revealed no change in the positive symptoms, but a small decrease in the negative symptoms and the general psychopathology of the patient. This was further illustrated by the small decrease in the number of depressive symptoms. The subjective sleep disorders improved markedly after acupuncture treatment, but the daytime sleepiness did not. The actiwatch results showed that after acupuncture treatment, the patient was moving less during sleep, but no significant results were found for the other sleep parameters.</P> <P><B>Conclusion</B></P> <P>Acupuncture was found to be an effective non-pharmacological add-on method for treating subjective sleep disorders, and, to a lesser degree, objective sleep disorders and the negative symptoms of chronic schizophrenia. Future larger clinical trials with follow-up measurements are needed in order to replicate the present preliminary beneficial acupuncture findings and in order to determine whether the observed effects can be sustained.</P>

Schizophrenia, Depression, and Sleep Disorders: Their Traditional Oriental Medicine Equivalents

Peggy Bosch,Peter de Rover,Heike Staudte,임사비나,Maurits van den Noort 사단법인약침학회 2015 Journal of Acupuncture & Meridian Studies Vol.8 No.1

Psychiatric disorders can be described and treated from both a Western (allopathic) and an Eastern perspective, which should be taken into account when conducting research. Patients with schizophrenia or depression are likely to be undergoing Western treatment when they are referred to an acupuncturist for (add-on) treatment, and knowledge of both types of treatments is necessary to integrate them successfully. In this study, the different traditional Oriental medicine (TOM) diagnostic patterns in patients with a Western diagnosis of schizophrenia, depression, or sleep disorders are described from a literature and a clinical perspective. The data on 30 depression and 30 schizophrenia patients from a German study are presented. Our results show that if a psychiatric group, sorted in accordance to Western diagnostic principles, is diagnosed on the basis of TOM diagnostic patterns, it can be categorized into different groups of patients with psychiatric disorders; this finding has far-reaching consequences in scientific research on acupuncture. Moreover, we found a high prevalence of sleep disorders in patients with both schizophrenia and depression, which could be explained from the perspective of a TOM diagnostic pattern. Finally, we discuss sleep quality as a treatment objective that may play a crucial role in mediating acupuncture-induced treatment effects in patients with schizophrenia and depression.

Schizophrenia, Depression, and Sleep Disorders: Their Traditional Oriental Medicine Equivalents

Bosch, P.,de Rover, P.,Staudte, H.,Lim, S.,van den Noort, M. Elsevier Science B.V., Amsterdam 2015 JOURNAL OF ACUPUNCTURE AND MERIDIAN STUDIES Vol.8 No.1

Psychiatric disorders can be described and treated from both a Western (allopathic) and an Eastern perspective, which should be taken into account when conducting research. Patients with schizophrenia or depression are likely to be undergoing Western treatment when they are referred to an acupuncturist for (add-on) treatment, and knowledge of both types of treatments is necessary to integrate them successfully. In this study, the different Traditional Oriental Medicine (TOM) diagnostic patterns in patients with a Western diagnosis of schizophrenia, depression, or sleep disorders are described from a literature and a clinical perspective. The data on 30 depression and 30 schizophrenia patients from a German study are presented. Our results show that if a psychiatric group, sorted in accordance to Western diagnostic principles, is diagnosed on the basis of TOM diagnostic patterns, it can be categorized into different groups of patients with psychiatric disorders; this finding has far-reaching consequences in scientific research on acupuncture. Moreover, we found a high prevalence of sleep disorders in patients with both schizophrenia and depression, which could be explained from the perspective of a TOM diagnostic pattern. Finally, we discuss sleep quality as a treatment objective that may play a crucial role in mediating acupuncture-induced treatment effects in patients with schizophrenia and depression.

Remote-Controlled Experiment with Integrated Verification of Learning Outcome

Staudt, Volker,Menzner, Stefan,Baue, Pavol The Korean Institute of Power Electronics 2010 JOURNAL OF POWER ELECTRONICS Vol.10 No.6

Experiments in electrical engineering should mirror the key components of successful research and development: Understand the basic theory needed, test the resulting concepts by simulation and verify these, finally, in the experiment. For optimal learning outcome continuous monitoring of the progress of each individual student is necessary, immediately repeating those subjects which have not been learned successfully. Classically, this is the task of the teacher. In case of remote-controlled experiments this monitoring process and the repetition of subjects should be automated for optimal learning outcome. This paper describes a remote-controlled experiment combining theory, simulation and the experiment itself with an automated monitoring process. Only the evaluation of the experimental results and their comparison to the simulation results has to be checked by a teacher. This paper describes the details of the educational structure for a remote-controlled experiment introducing active filtering of harmonics. For better understanding the content of the learning material (theory and simulation) as well as the results of the experiment and the underlying booking system are shortly presented.

Advanced Simulation Concept for the Power Train of an AC Locomotive and its Verification

Volker Staudt,Carsten Heising,A. Steimel 전력전자학회 2007 ICPE(ISPE)논문집 Vol.- No.-

Recent AC railway traction vehicles contain two main power electronic components in the power train, the four-quadrant converter and the three-phase machine-side inverter. They are joined by a common DC-link capacitor and ? often ? a resonant circuit tuned to twice the supply frequency. Converter and inverter are mainly controlled separately. The overall performance of the traction vehicle can be improved considerably by an integrated control of converter and inverter, explicitly taking into account the dynamics of the DC-link filter. This requires, however, enhanced control and simulation effort. The simulation has to deal with a hybrid system, described on the one hand by continuous differential equations and on the other hand by converter switching functions. The continuous part of the system is described by state-space equations solved by the Bulirsch-Stoer implementation of the Richardson Extrapolation, the switchings are modeled using Petri Nets. This combination allows high-speed simulations of the complete system at suitable precision. For verification the simulation results are compared to measurements made at a 50-㎾ laboratory test set-up of the complete power train. At this early stage of the project, simple control schemes are used for first tests of simulation and test set-up. Measured and simulated quantities are in very good agreement, allowing to proceed to more sophisticated control schemes.

Remote-Controlled Experiment with Integrated Verification of Learning Outcome

Volker Staudt,Stefan Menzner,Pavol Bauer 전력전자학회 2010 JOURNAL OF POWER ELECTRONICS Vol.10 No.6

Experiments in electrical engineering should mirror the key components of successful research and development: Understand the basic theory needed, test the resulting concepts by simulation and verify these, finally, in the experiment. For optimal learning outcome continuous monitoring of the progress of each individual student is necessary, immediately repeating those subjects which have not been learned successfully. Classically, this is the task of the teacher. In case of remote-controlled experiments this monitoring process and the repetition of subjects should be automated for optimal learning outcome. This paper describes a remote-controlled experiment combining theory, simulation and the experiment itself with an automated monitoring process. Only the evaluation of the experimental results and their comparison to the simulation results has to be checked by a teacher. This paper describes the details of the educational structure for a remote-controlled experiment introducing active filtering of harmonics. For better understanding the content of the learning material (theory and simulation) as well as the results of the experiment and the underlying booking system are shortly presented.

The bio-complex reaction pattern in vertebrate cells reduces cytokine-induced cellular adhesion molecule mRNA expression in human endothelial cells by attenuation of NF-kappaB translocation

( Cindy Ronnau ),( Herbert E. H. Liebermann ),( Franz Helbig ),( Alexander Staudt ),( Stephan B. Felix ),( Ralf Ewert ),( Martin Landsberger ) 생화학분자생물학회 2009 BMB Reports Vol.42 No.2