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RISS 인기검색어
- 검색키워드
- 저자 : Shihua Zhao (검색결과 4 건)
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Expression of Yeast YAP1 in Transgenic Arabidopsis Results in Increased Salt Tolerance
Jiqiang Zhao,Shanli Guo,Shihua Chen,Hui Zhang,Yanxiu Zhao 한국식물학회 2009 Journal of Plant Biology Vol.52 No.1
Soil salinity is a major abiotic stress that lowers agricultural production around the world. Mainly caused by elevated levels of NaCl, it induces a wide range of responses in plants. In addition to ion toxicity, high salt levels can induce oxidative stress with the formation and accumulation of reactive oxygen species (ROS). We introduced the transcription factor YAP1, originally from yeast (Saccharomyces cerevisiae), into Arabidopsis thaliana (ecotype Columbia). When treated with various NaCl concentrations, transgenic plants showed increased activities of antioxidant enzymes catalase, superoxide dismutase, ascorbate peroxidase, peroxidase, glutathione S-transferase, and glutathione reductase compared with the wild-type Arabidopsis. This demonstrated that an active oxygen scavenging system was enhanced to protect plants from salt stress by equilibrating ROS metabolism. Transgenic Arabidopsis maintained higher photosynthesis levels and lower amounts of H2O2, suggesting that ROS production was reduced. Physiological analysis implied that transgenic Arabidopsis might employ multiple mechanisms to improve its salt tolerance.
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Chen Cui,Xinyu Wang,Shihua Zhao 아시아심장혈관영상의학회 2020 Cardiovascular Imaging Asia Vol.4 No.3
A 35-year-old male with 7-year history of exertional dyspnea and abdominal distention had frequent premature ventricular contractions detected by Holter monitoring. Cardiovascular magnetic resonance (CMR) imaging demonstrated a significantly dilated left ventricle (LV) with severely reduced global systolic function. Coronary arterial stenosis was excluded with CT coronary angiography. However, transmural late gadolinium enhancement was detected by CMR in the lateral wall of the LV. The patient received cardiac transplantation. The diagnosis of left dominant arrhythmogenic right ventricular cardiomyopathy was made.
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Zhentao Li,Jie Dong,Jian Huang,Tao Guo,Shihua Wang,Xin Zhao,Qinghua Zhang 한국고분자학회 2020 Macromolecular Research Vol.28 No.1
In this work, two sets of high performance polyimide (PI) fibers fabricated by a more environmentally-friendly and highly efficient “reaction-spinning” method were firstly reported. The relationship between the spinning rate, chemical structure and the imidization degree of the PI precursor fibers were investigated, and the results indicated a moderate low spinning speed and relatively flexible molecular chains are both favorable for the partial imidization reaction in the spinning process. 2D WAXD results demonstrate that the rigid PDA-based PI fibers possess a higher alignment of polymer chains along the fiber axis during the spinning compared to the flexible ODA-based PIs, resulting in enhanced mechanical properties, with the tensile strength of 1.2-2.8 GPa and modulus of 53.6-111.2 GPa, respectively. Meanwhile, ODA sets of PI fibers exhibit a higher loop strength and knot strength than the commercial Aramid and PBO fibers. The process used in this study has a significant potential for realizing industrial level production of high strength and high modulus PI fibers.
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Chen Cui,Gang Yin,Minjie Lu,Xiuyu Chen,Sainan Cheng,Lu Li,Weipeng Yan,Yanyan Song,Sanjay Prasad,Yan Zhang,Shihua Zhao 대한영상의학회 2019 Korean Journal of Radiology Vol.20 No.1
Objective: Segmented cardiac cine magnetic resonance imaging (MRI) is the gold standard for cardiac ventricular volumetric assessment. In patients with difficulty in breath-holding or arrhythmia, this technique may generate images with inadequate quality for diagnosis. Real-time cardiac cine MRI has been developed to address this limitation. We aimed to assess the performance of retrospective electrocardiography-gated real-time cine MRI at 3T for left ventricular (LV) volume and mass measurement. Materials and Methods: Fifty-one patients were consecutively enrolled. A series of short-axis cine images covering the entire left ventricle using both segmented and real-time balanced steady-state free precession cardiac cine MRI were obtained. End-diastolic volume (EDV), end-systolic volume (ESV), stroke volume (SV), ejection fraction (EF), and LV mass were measured. The agreement and correlation of the parameters were assessed. Additionally, image quality was evaluated using European CMR Registry (Euro-CMR) score and structure visibility rating. Results: In patients without difficulty in breath-holding or arrhythmia, no significant difference was found in Euro-CMR score between the two techniques (0.3 ± 0.7 vs. 0.3 ± 0.5, p > 0.05). Good agreements and correlations were found between the techniques for measuring EDV, ESV, EF, SV, and LV mass. In patients with difficulty in breath-holding or arrhythmia, segmented cine MRI had a significant higher Euro-CMR score (2.3 ± 1.2 vs. 0.4 ± 0.5, p < 0.001). Conclusion: Real-time cine MRI at 3T allowed the assessment of LV volume with high accuracy and showed a significantly better image quality compared to that of segmented cine MRI in patients with difficulty in breath-holding and arrhythmia.
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