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      • 서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

        김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

        In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

      • SCOPUSKCI등재

        Bucillamine prevents cisplatin-induced ototoxicity through induction of glutathione and antioxidant genes

        Kim, Se-Jin,Ho Hur, Joon,Park, Channy,Kim, Hyung-Jin,Oh, Gi-Su,Lee, Joon No,Yoo, Su-Jin,Choe, Seong-Kyu,So, Hong-Seob,Lim, David J,Moon, Sung K,Park, Raekil Nature Publishing Group 2015 Experimental and molecular medicine Vol.47 No.2

        <P>Bucillamine is used for the treatment of rheumatoid arthritis. This study investigated the protective effects of bucillamine against cisplatin-induced damage in auditory cells, the organ of Corti from postnatal rats (P2) and adult Balb/C mice. Cisplatin increases the catalytic activity of caspase-3 and caspase-8 proteases and the production of free radicals, which were significantly suppressed by pretreatment with bucillamine. Bucillamine induces the intranuclear translocation of Nrf2 and thereby increases the expression of γ-glutamylcysteine synthetase (γ-GCS) and glutathione synthetase (GSS), which further induces intracellular antioxidant glutathione (GSH), heme oxygenase 1 (HO-1) and superoxide dismutase 2 (SOD2). However, knockdown studies of HO-1 and SOD2 suggest that the protective effect of bucillamine against cisplatin is independent of the enzymatic activity of HO-1 and SOD. Furthermore, pretreatment with bucillamine protects sensory hair cells on organ of Corti explants from cisplatin-induced cytotoxicity concomitantly with inhibition of caspase-3 activation. The auditory-brainstem-evoked response of cisplatin-injected mice shows marked increases in hearing threshold shifts, which was markedly suppressed by pretreatment with bucillamine <I>in vivo</I>. Taken together, bucillamine protects sensory hair cells from cisplatin through a scavenging effect on itself, as well as the induction of intracellular GSH.</P>

      • 보행시 발생되는 하지 운동근의 장력과 관절 토오크의 수리적 해석

        홍성표,이순호 忠南大學校體育科學硏究所 1994 體育科學硏究誌 Vol.12 No.1

        The purpose of this study is to present the mathematical interpretation on joint torque while being normal gait which include the muscle tension and use equation of motion with a double rigid-pendulum model. then, the estimates of the stance and swing phase were obtained from photoghaphs. When the angel of thigh(θ₁) and calf (θ₂) of lower leg measured from vertical direction to counterclockwise are compared, the results as follow; 1. It is possible to interpret the mathematical model on the joint torque of lower extremity with double rigid pendulum model. 2. With the conition of double rigid pendulum model, the length of center of mass does not effect at the change of angle.

      • 상체의 중량 변화에 따른 보행의 운동현상학적 특성

        홍성표,이순호 忠南大學校體育科學硏究所 1991 體育科學硏究誌 Vol.9 No.1

        The purpose of this study was to find out the effect for carrying load of 20% & 40% of body weight by means of two different carrying systems on selected kinematic characteristic describe the walking gait patterns. 1. The gait cycle-time for loading of upperpart of body during walking gait was the longest at back pack system Ⅱ. The period of double support of back pack system condition tended to increase with loading of body and swing period tended to decrease. 2. Angle displacement of knee and ankle of joint was the most large at toe off phase and the most short at heel for gait cycle period. The angle displacement of ankle and knee in the condition of exteral load of body was slight increase at double pack system condition and decrease at back pack system condition. 3. The body posture and gait pattern for double pack condition were more similar to those for normal walking than for the back pack system condition, suggest that the double pack system was Kinematically more effective than the conventional back pack system for carrying the loads investigated.

      • KCI등재

        생검펀치를 이용한 점액낭종의 절제

        홍은혜,최병재,이제호,최형준,손흥규,김성오 대한소아치과학회 2007 大韓小兒齒科學會誌 Vol.34 No.2

        점액낭종은 소타액선 분비관의 폐쇄나 파열로 타액이 저류되어 발생하는 연조직 부종이고, 비교적 높은 빈도로 발생하는 구강내 가성 낭종으로 스스로 파열되어 치유되기도 하지만 대개는 만성적으로 진행되어 몇 주에서 몇 달간 지속되기 때문에 치료가 필요하다. 점액 낭종의 발생시, 주변에 이환된 소타액선을 포함하여 제거하는 완전절제술 외에 재발율을 낮추기 위한 스테로이드의 국소적 주입, 냉동동결요법(cryotherapy), 미세조대술(micromarsupialization) 등의 여러 가지 치료방법이 제시되고 있다. 완전절제술의 한 방법으로 생검펀치(biopsy punch)를 이용할 수 있는데, 조작이 간편하고 출혈이 적으며 술 후 처치가 거의 필요없다는 장점이 있다. 이 증례는 점액낭종이 있고 행동 조절이 힘든 소아에서 생검펀치를 사용하여 점액낭종을 완전히 제거한 경우로, 양호한 결과를 얻었다. Mucocele is a clinical term of the localized superficial mucosal swelling caused by salivary retention after the obstruction or the rupture of minor salivary ducts. Various treatment methods have been suggested to lower its recurrence rate, including complete excision of lesion Biopsy punch can be used easily and simply for complete excision of mucocele. It has several advantages, such as convenience in use, low bleeding tendency, and nearly no requirements for post-operative management. In this case, biopsy punch was used for the removal of mucocele in an uncooperative child, which enable fast, simple and safe procedure, with a good result.

      • 인터넷 캐쉬를 위한 멀티미디어 데이터의 재배치 정책

        홍현옥,임은지,박성호 동의공업대학 2000 論文集 Vol.26 No.1

        Through the dramatic growth of Internet, it becomes easy for people to access geographically distributed vast amounts of information. But, currently Internet is suffering from problems such as server overload, network congestion and client response time. In addition, currently the number of continuous media data such as audio and video is growing rapidly. In this paper, we propose SCU(Smallest Caching Utility) proxy caching scheme that stores a portion of continuous media stream or entire stream on the Internet. The proposed scheme reduces client latency and maximizes the amount of data served directly from cache without accessing the central server. By caching the initial fraction of stream data, service startup latency can be reduced. And, by varying the size of the fraction of stream to be cached according to variation of stream popularity, we can utilize the cache space efficiently and maximize the amounts of data served directly from cache. We use the caching utility formula of each stream for the measurement of cache replacement. The way to measure popularity of continuous media stream should be different from that of traditional data such as text and image. We propose the method of measuring popularity of stream using the amounts of data played by clients. We have performed simulations to evaluate our caching policy, Simulation results show that our caching policy outperforms other caching algorithms such as LRU, LFU and SIZE in aspects of BHR(byte hit ratio), initial latency and replacement overhead.

      • KCI등재후보

        CMP 폐액의 고액분리에서 응집제의 영향에 관한 연구

        홍성호,오석환 대한상하수도학회 2002 상하수도학회지 Vol.16 No.2

        A coagulation was applied to separate the solid and liquid from waste CMP generated from the CMP process. Three different coagulants - PACl, MgCl_2 and Ca(OH)^2 was used to find the best coagulant and optimum condition of each coagulant for water and solid recovery. When the solid content was 0.lwt%, the adequate flocculation speed was 10 to 30 rpm for PACl. However, the flocculation speed was not critical for MgCl_2 and Ca(OH)_2 at any dosage. Minimum sedimentation time was 30 minutes to get less than 1NTU of turbidity, the sludge volume was 10 to 15% and 50 to 55% for 0.1wt% and 0.5wt% of waste CMP slurry, respectively. According to the experimental results such as turbidity, zeta potential and heavy metal concentration in the supernatant PACl was the best coagulant for water recovery.

      • 벼 직파재배 기계화 기술개발에 관한 고찰

        홍종호,이성범,김성엽 안성산업대학교 2002 論文集 Vol.33 No.-

        This study was conducted to suggest the mechanization strategy for rice direct seeding cultivation through reviewing the current rice cultivation status and its problem. The rice direct seeding cultivation can contribute to reduce production cost as well as to enhance the mechanization technology and related machine development. The objects and directions for rice direct seeding cultivation strategy, reviewed in this study, could be summarized as follows : 1. The breeding status for direct seeding cultivation is less uniform than transplanting cultivation, especially in large scale farming area. So, precision farming techniques for the operations such as seeding, fertilizing, water control etc., and proper farm machinery utilization system suitable for large scale farming area should be identified and introduced. 2. In order to get the effect of direct seeding cultivation such as reduction in production cost and save labor requirement, the following seeding machines should be developed and used in direct seeding cultivation, i.e. no or partial plowing machine, direct seeder for dry field, and direct seeder for wet field, which can be used for simultaneous operation of seeding, fertilizing, and weeding. 3. Governmental & private organizations concerned with agriculture and farm machinery should agree positively with the direct seeding cultivation policy. 4. It is urgent that development of precision farming technology and its mechanization suitable for korean field conditions with the assistance of information technology such as GPS and GIS.

      • 자전거의 페달반력 측정 시스템 개발

        홍성표,이창섭,이순호 忠南大學校體育科學硏究所 1997 體育科學硏究誌 Vol.15 No.1

        The purpose of this study was to develop the measurement system of pedal reaction-force for the bicycle that measures two-dimension force with loadcell on the pedal. The system consisted of sensor part, data collection part and software part for control. The sensor part consisted of preamplier and signal condition circuit. It was consisted of high intensity circuit to decrease the noise and to improve response trait. The data collection part with 12 bit was collected for the data by timing mode on trigger signal. The signal of the sensor was controlled for the sampling speed by way of the software in computer. Measuring system on pedal reaction force testified the utilization through calibration and the experimental test.

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