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경주국립공원 문화재지정구역의 귀화식물 현황 및 관리방안
윤정원 ( Jung Won Yoon ),신현탁 ( Hyun Tak Shin ),이명훈 ( Myung Hoon Yi ),김기송 ( Gi Song Kim ),성정원 ( Jung Won Sung ),박기환 ( Ki Hwan Park ),이창현 ( Chang Hyun Lee ),김용식 ( Yong Shik Kim ) 한국환경생태학회 2012 한국환경생태학회지 Vol.26 No.4
경주국립공원 문화재지정구역에 분포하는 귀화식물은 총 14과 40속 45종 1변종 등 총 46분류군을 확인하였다. 귀화식물을 유형별로 구별해보면, 생활형은 1년생 초본이 17분류군(37%)으로 가장 많았으며, 다년생 초본이 16분류군 (34.8%), 2년생 초본이 11분류군(23.9%), 목본이 2분류군(4.3%)로 나타났다. 원산지 별로는 유럽이 17분류군(37%)으로 가장 많았으며, 그 다음으로 북아메리카에서 이입된 종이 16분류군(34.8%)으로 나타났다. 또한 귀화도는 3등급이 18분류군(40.9%)으로 가장 높다. 귀화식물 321분류군에 대한 본 연구대상지의 도시화 지수는 14.3%이며, 지구별 도시화 지수는 남산지구가 8.1%로 가장 높다. 경주국립공원은 사적형 공원으로 문화재가 매우 중요하나, 문화재 주변의식재 및 관리 또한 중요하다. 따라서 귀화식물의 경우 장기적인 모니터링과 생태적인 특성을 파악하여 체계적인 관리방안이 요구된다. The naturalized plant species in Gyeongju National Park was summarized as 46taxa including 14 families 40 genus 45 species 1 varieties. Among them, annual herbaceous species was 17taxa (37%) which is grouped as the biggest proportion and 16taxa (34.8%) for perennial herbaceous species and 11taxa (23.9%) for biannual herbaceous species and 2taxa (4.3%) for tree species. European origin was the biggest proportion as 17taxa (37%), and 16% (34.8%) from North America. The degree of naturalization (DoN) was the biggest for Degree III, V as 18taxa (39.1%). Regarding 321 naturalized plant species, the Urbanization Index in the studied area was 14.3%. The Namsam District showed 8.1% which is the highest DoN in the studied districts within the Gyeongju National Park. As the cultural properties is important in the Gyeongju National Park as a representatives for historical sites in Korea, planting and its management in the cultural properties is important tasks. The naturalized plant species in the studied area should be reasonably management.
윤정원 ( Jung Won Yoon ),김용식 ( Yong Shik Kim ),신현탁 ( Hyun Tak Shin ),김기송 ( Gi Song Kim ),성정원 ( Jung Won Sung ),이창현 ( Chang Hyeon Lee ),박기환 ( Ki Hwan Park ),이명훈 ( Myung Hoon Yi ) 한국환경생태학회 2013 한국환경생태학회지 Vol.27 No.2
본 연구는 경주국립공원(남산, 토함산, 단석산)의 관속식물상을 밝히고 주요 식물들의 분포를 조사하였다. 2011년 7월부터 2012년 5월까지 총 7회 조사하였다. 조사결과 관속식물은 96과 284속 385속 4아종 41변종 6품종으로 총 436분류군을 확인하였다. 그 중 산림청 지정 희귀식물은 7분류군, 특산식물은 13분류군이다. 식물구계학적 특정식물은 41분류군으로 Ⅴ등급 1분류군, Ⅳ등급 3분류군, Ⅲ등급 9분류군, Ⅱ등급 4분류군,Ⅰ등급 24분류군이다. 한편 귀화식물은 29분류군으로 확인하였으며, 귀화율은 6.65%, 도시화지수는 9.03%이다. 조사된 436분류군의 유용도는 목초용 자원식물이 182분류군(41.7%), 식용 176분류군(40.4%), 약용 147분류군(33.7%), 관상용 52분류군(11.9%), 목재용 18분류군(4.1%), 염료용 16분류군(3.7%), 섬유용 8분류군(1.8%), 공업용 자원식물이 1분류군(0.2%) 그리고 용도가 밝혀지지 않은 식물이 79분류군(18.1%)으로 나타났다. This study was carried out to investigate the vascular flora of Mt. Nam, Mt. Toham, and Mt. Danseok in Gyeongju National Park . The vascular plants were surveyed for 7 times from July 2011 to May 2012. The results were summarized as 436 taxa, 96families, 284 genera, 385 species, 4 subspecies, 41 varieties, and 6 forms. The 13 taxa were categorized as Korean endemic plants species and the other 7 taxa as rare plants species, which categorized by the Korea Forest Service. Based on the Floristic Degrees categorized by the Specific Distribution of Plants Species, one taxa grouped as the Floristic Degree Ⅴ, 3 for Floristic Degree Ⅳ, and 9 for Floristic Degree Ⅲ, 4 for Floristic Degree Ⅱ, and 24 taxa for Floristic Degree I. The naturalized plants were recorded as 29 taxa, and their Naturalization Ratio and Urbanization Index were recorded as 6.65%, and 9.03%, respectively. 436 taxa listed consists of 182 taxa(41.7%) of pasturing plant, 176 taxa(40.4%) of edible plants, 147 taxa(33.7%) of medicinal plants, 52 taxa(11.9%) of ornamental plants, 18 taxa(4.1%) of timber plants, 16 taxa(3.7%) of stain plants, 8 taxa(1.8%) of fiber plants, 1 taxa(0.2%) of industrial plants and 79 taxa(18.1%) of unknown plants.
Chansong Kim,Jin Woong Lee,허준혁,Cheolhyun Park,Dai-Hwan Kim,Gyu Sung Yi1,Ho Chang Kang,Hyun Suk Jung,Hyunjung Shin,Jung Heon Lee 한국생체재료학회 2022 생체재료학회지 Vol.26 No.1
Background: A considerable number of studies has been carried out to develop alloplastic bone graft materials such as hydroxyapatite (HAP) that mimic the hierarchical structure of natural bones with multiple levels of pores: macro-, micro-, and nanopores. Although nanopores are known to play many essential roles in natural bones, only a few studies have focused on HAPs containing them; none of those studies investigated the functions of nanopores in biological systems. Method: We developed a simple yet powerful method to introduce nanopores into alloplastic HAP bone graft materials in large quantities by simply pressing HAP nanoparticles and sintering them at a low temperature. Results: The size of nanopores in HAP scaffolds can be controlled between 16.5 and 30.2 nm by changing the sintering temperature. When nanopores with a size of ~ 30.2 nm, similar to that of nanopores in natural bones, are introduced into HAP scaffolds, the mechanical strength and cell proliferation and differentiation rates are significantly increased. The developed HAP scaffolds containing nanopores (SNPs) are biocompatible, with negligible erythema and inflammatory reactions. In addition, they enhance the bone regeneration when are implanted into a rabbit model. Furthermore, the bone regeneration efficiency of the HAP-based SNP is better than that of a commercially available bone graft material. Conclusion: Nanopores of HAP scaffolds are very important for improving the bone regeneration efficiency and may be one of the key factors to consider in designing highly efficient next-generation alloplastic bone graft materials.
Shin, Minkyung,Yi, Eun Hee,Kim, Byung-Hak,Shin, Jae-Cheon,Park, Jung Youl,Cho, Chung-Hyun,Park, Jong-Wan,Choi, Kang-Yell,Ye, Sang-Kyu Korean Society for Molecular and Cellular Biology 2016 Molecules and cells Vol.39 No.11
The ${\beta}$-catenin functions as an adhesion molecule and a component of the Wnt signaling pathway. In the absence of the Wnt ligand, ${\beta}$-catenin is constantly phosphorylated, which designates it for degradation by the APC complex. This process is one of the key regulatory mechanisms of ${\beta}$-catenin. The level of ${\beta}$-catenin is also controlled by the E3 ubiquitin protein ligase SIAH-1 via a phosphorylation-independent degradation pathway. Similar to ${\beta}$-catenin, STAT3 is responsible for various cellular processes, such as survival, proliferation, and differentiation. However, little is known about how these molecules work together to regulate diverse cellular processes. In this study, we investigated the regulatory relationship between STAT3 and ${\beta}$-catenin in HEK293T cells. To our knowledge, this is the first study to report that ${\beta}$-catenin-TCF-4 transcriptional activity was suppressed by phosphorylated STAT3; furthermore, STAT3 inactivation abolished this effect and elevated activated ${\beta}$-catenin levels. STAT3 also showed a strong interaction with SIAH-1, a regulator of active ${\beta}$-catenin via degradation, which stabilized SIAH-1 and increased its interaction with ${\beta}$-catenin. These results suggest that activated STAT3 regulates active ${\beta}$-catenin protein levels via stabilization of SIAH-1 and the subsequent ubiquitin-dependent proteasomal degradation of ${\beta}$-catenin in HEK293T cells.
Study on the Ophthalmic Diseases in ICR Mice and BALB/c Mice
PARK, Shin Ae,JEONG, Seong Mok,YI, Na Young,KIM, Min Su,JEONG, Man Bok,SUH, Jun Gyo,OH, Yang Seok,WON, Moo Ho,NAM, Tchi Chou,PARK, Jae Hak,SEO, Kang Moon Japanese Association for Laboratory Animal Science 2006 Experimental animals Vol.55 No.2
<P>In pharmaceutical companies and research institutes, many toxicity tests are performed with laboratory animals. This study was performed to produce reference data for eye toxicity tests and to investigate the ophthalmic diseases of 408 ICR mice and 119 BALB/c mice, which are commonly used as subjects in toxicity tests. The experimental animals without clinical disorders were selected regardless of sex. The ophthalmic diseases were examined by using special ophthalmic instruments: direct ophthalmoscope, indirect ophthalmoscope, slit-lamp biomicroscope and focal illuminator. The most prevalent ocular variation within normal limits was hyaloid vessel remnant (ICR mice, 28.2%; BALB/c mice, 31.9%) and the incidence gradually decreased with age. The ocular diseases found in ICR mice were retinal degeneration (9.8%), corneal scar (4.2%), focal cataract (2.2%), anisocoria (1.2%), corneal ulcer (0.2%) and uveitis (0.2%). In BALB/c mice, corneal scar (9.2%), focal cataract (1.7%) and corneal ulcer (0.8%) were the ocular diseases found.</P>
Park Shin Young,Choi Gawon,Lee Hyeyoung,Kim Na-young,Lee Seon-young,Kim Kyungnam,Shin Soyoung,Jang Eunsu,Moon YoungSin,Oh KwangHwan,Choi JaeRin,Lee Sang-Eun,Kim Young-Man,Kim Jieun,Yi Seonju,Gwack Jin 질병관리본부 2020 Osong Public Health and Research Persptectives Vol.11 No.4
This study describes the epidemiological characteristics of coronavirus disease 2019 (COVID-19) based on reported cases from long-term care facilities. As of April 20th, 2020, 3 long-term care facilities in a metropolitan area of South Korea had reported cases of COVID-19. These facilities’ employees were presumed to be the sources of infection. There were 2 nursing hospitals that did not report any additional cases. One nursing home had a total of 25 cases, with an attack rate of 51.4% (95% CI 35.6–67.0), and a fatality rate of 38.9% (95% CI 20.3–61.4) among residents. The results from this study suggest that early detection and maintenance of infection control minimizes the risk of rapid transmission.
Park, Shin-Young,Cho, Ju Hwan,Oh, Doo-Yi,Park, Jung-Won,Ahn, Myung-Ju,Han, Joong-Soo,Oh, Jae-Won American Society for Biochemistry and Molecular Bi 2009 The Journal of biological chemistry Vol.284 No.30
<P>The purpose of this study was to identify the role of phospholipase D1 (PLD1) in Der f 2-induced interleukin (IL)-13 production. The major house dust mite allergen, Der f 2, increased PLD activity in human bronchial epithelial cells (BEAS-2B), and dominant negative PLD1 or PLD1 siRNA decreased Der f 2-induced IL-13 expression and production. Treatment of Der f 2 activated the phospholipase Cgamma (PLCgamma)/protein kinase Calpha (PKCalpha)/p38 MAPK pathway. Der f 2-induced PLD activation was attenuated by PLCgamma inhibitors (U73122 and PAO), PKCalpha inhibitors (RO320432 and GO6976), and p38 MAPK inhibitors (SB203580 and SB202190). These results indicate that PLCgamma, PKCalpha, and p38 MAPK act as upstream activators of PLD in Der f 2-treated BEAS-2B cells. Furthermore, expression and production of IL-13 increased by Der f 2 were also blocked by inhibition of PLCgamma, PKCalpha, or p38 MAPK, indicating that IL-13 expression and production are related to a PLCgamma/PKCalpha/p38 MAPK pathway. We found that activating transcription factor-2 (ATF-2) was activated by Der f 2 in BEAS-2B cells and activation of ATF-2 was controlled by PLD1. When ATF-2 activity was blocked with ATF-2 siRNA, Der f 2-induced IL-13 expression and production were decreased. Thus, ATF-2 might be one of the transcriptional factors for the expression of IL-13 in Der f 2-treated BEAS-2B cells. Taken together, PLD1 acts as an important regulator in Der f 2-induced expression and production of IL-13 through activation of ATF-2 in BEAS-2B cells.</P>
Distribution of Rare Plants and Endemic Plants in Jirisan National Park
Shin, Hyun-Tak,Yi, Myung-Hoon,Yoon, Jung-Won,Yoo, Ji-Hyun,Lee, Byoung-Chun,Park, Eun-Hee national science museum of korea 2010 Journal of Korean nature Vol.3 No.4
The results of the study of the rare and regional species of the Jirisan (Mt.) Korea National Park has reported 3 CR species, including the Allium victorialis var. platyphyllum, 4 EN species, including Rhododendron tschonoskii, 7 VU species, including Cacalia pseudo-taimingasa, 11 LC species, including Lilium distichum, and 3 DD species, including Aconitum chiisanense, which makes a total of 28 species. In terms of species exclusive to the region, a total of 7 species, including Fraxinus chiisanensis, Pseudostellaria heterophylla, Filipendula formosa and Cirsium chanroenicum, were confirmed, and since they were distributed widely in the Jeonji region of Jirisan (Mt.), there was minimal damage. Since rare species are localized in the region of Agosan (Mt.), there has been continuous damage due to visitors and hikers to the area, and there seems to be the need to handle the decreasing habitat for Allium victorialis var. platyphyllum, Juniperus chinensis var. sargentii and Trientalis europaea.