Antinociceptive and anti-inflammatory activities of Pandanus fascicularis Lamk. leaves in animal models

Panda, Prabhudutta,Panda, DP,Panda, PK,Nayak, SS Kyung Hee Oriental Medicine Research Center 2008 Oriental pharmacy and experimental medicine Vol.7 No.5

The present study was carried out to elucidate the potential of, chloroform extract of Pandanus (P.) fascicularis Lamk (Family-Pandanaceae) leaves on antinociceptive, behavioral study and anti-inflammatory effects using various animal models The dried, powdered leaves of, P. fascicularis were extracted successively with petroleum ether ($60\;-\;80^{\circ}C$) and chloroform in soxhlet apparatus. The chloroform extract (yield 21.6% w/w with respected to dry powdered plant material) was selected for all experimental procedure. Two models were employed to investigate the effects on nociception, the tail immersion and hot plate method in Swiss albino mice and anti inflammatory effect were investigated by employing the carrageenan induced rat paw edema test in. adult Wister albino rats. Behavioral study was investigated by elevated plus maze method in Swiss albino mice. Results were revealed that the PFCE was found significant antinociceptive effect (P < 0.001) at the dose levels of 100, 200 and 400 mg/kg, orally in mice and produced remarkable antiinflammatory effect (P < 0.001) at the same dose levels used in the rats. Behavioral study of the PFCE has no significant anxiolysis effect when used orally. It concludes that, PFCE possessed remarkable antinociceptive effect and anti-inflammatory effect but no anxiolytic effect on animal models.

Numerical modeling and prediction of adhesion failure of adhesively bonded composite T-Joint structure

Subhransu K Panda,Pradeep K Mishra,Subrata K. Panda 국제구조공학회 2020 Structural Engineering and Mechanics, An Int'l Jou Vol.74 No.6

This study is reported the adhesion failure in adhesive bonded composite and specifically for the T-joint structure. Three-dimensional finite element analysis has been performed using a commercial tool and the necessary outcomes are obtained via an eight noded solid element (Solid 185-element) from the library of ANSYS. The structural analysis input has been incurred through ANSYS parametric design language (APDL) code. The normal and shear stress distributions along different layers of the joint structure have been evaluated as the final outcomes. Based on the stress distributions, failure location in the composite joint structure has been identified by using the Tsai-Wu stress failure criterion. It has been found that the failure index is maximum at the interface between flange and web part of the joint (top layer) which indicates the probable location of failure initiation. This kind of failures are considered as adhesion failure and the failure propagation is governed by strain energy release rate (SERR) of fracture mechanics. The different adhesion failure lengths are also considered at the failure location to calculate the SERR values i.e. mode I fracture (opening), mode II fracture (sliding) and mode III fracture (tearing) along the failure front. Also, virtual crack closure technique (VCCT) principle of fracture mechanics steps is used to calculate the above said SERRs. It is found that the mode I SERR is more dominating compared to other two modes of failure for the joint considered. Finally, the influences of various parametric (geometrical and material) effect on SERR of the joint structure are evaluated and discussed in details.

Plasma plume behavior of laser ablated cerium oxide: Effect of oxygen partial pressure

Panda, Arun Kumar,Singh, Akash,Mishra, Maneesha,Thirumurugesan, R.,Kuppusami, P.,Mohandas, E. Cambridge University Press 2014 Laser and particle beams Vol.32 No.3

<B>Abstract</B><P>This paper describes the spatial and temporal investigation of laser ablated plasma plume of cerium oxide target using Langmuir probe. Cerium oxide target was ablated using a KrF (λ ~ 248 nm) gas laser. Experimental studies confirmed that oxygen partial pressure of 2 × 10<SUP>−2</SUP> mbar is sufficient enough to get good quality films of cerium oxide. At this pressure, plume was diagnosed for their spatial and temporal behavior. Spatial distribution was investigated at a distance of 15 mm, 30 mm, and up to a maximum distance of 45 mm from the target, whereas temporal behavior has been recorded in the range of 0 to 50 µS with an interval of 0.5 µS. The average electron densities are found to be maximum at 30 mm from the target position and the plasma current of the laser ablated ceria is found to be maximum at 22 µS.</P>

Effects of Dietary Non-phytate Phosphorus Levels on Egg Production, Shell Quality and Nutrient Retention in White Leghorn Layers

Panda, A.K.,Rao, S.V.Rama,Raju, M.V.L.N.,Bhanja, S.K. Asian Australasian Association of Animal Productio 2005 Animal Bioscience Vol.18 No.8

An experiment was conducted (28 to 44 weeks) to study the laying performance, shell quality, and nutrient retention of White Leghorn layers fed different levels of non-phytate phosphorus (NPP). Six levels of NPP (0.15, 0.18, 0.21, 0.24, 0.27 and 0.30%) at a constant calcium (Ca) level (3.5%) in maize-soya-deoiled rice bran based diets were formulated, and each experimental diet was offered ad libitum for 16 weeks to five replicates with five birds in each replicate. The body weight of WL layers fed diet containing 0.15% NPP was significantly (p<0.05) lower than those fed diet with 0.30% NPP, at 44 weeks of age. However, the hen day egg production, egg weight, daily feed intake and feed consumed per dozen eggs were not influenced by the variation in the NPP levels in the diet. The bone ash content was significantly (p<0.05) higher in the birds fed 0.30% NPP as compared with those fed diets up to 0.24% NPP. Bone ash content was intermediate in the birds fed diet containing 0.27% NPP. The tibia strength followed the same trend as that of bone ash. Dietary NPP content had no influence on serum Ca and protein concentration and activity of alkaline phosphatase. However, serum inorganic P concentration increased linearly with NPP content in the diet. The concentration of P was significantly (p<0.05) higher in the birds fed 0.27% NPP or higher as compared with those fed 0.15% NPP. Levels of dietary NPP had no influence on egg quality parameters like shell wt, shell thickness, shell strength and specific gravity. The retention of nutrients such as DM, N and Ca were comparable among the WL layers fed different levels of NPP. However, the retention of P decreased linearly with increase in the level of NPP in the diet. The retention of P in the birds fed diets up to 0.24% NPP in the diet was comparable, however further increasing the content of NPP (either 0.27% or 0.30%) reduced the retention of P. Based on the results of the present study, 0.15% NPP (180 mg/b/d) in the diets of WL layers is adequate for optimum production performance during 28 to 44 weeks of age, however, WL layers require 0.27% NPP (324 mg /b/d) in the diet for optimum production with better bone mineralization.

Synergistic interactions of Aegle marmelos leaf, Emblica officinalis fruit and Ocimum sanctum leaf extracts in the regulation of hyperthyroidism and / or hyperglycaemia

Panda, Sunanda,Kar, Anand Kyung Hee Oriental Medicine Research Center 2004 Oriental pharmacy and experimental medicine Vol.4 No.1

The effects of Aegle marmelos (Rutaceae) leaf, Emblica officinalis (Euphorbiaceae) fruit and Ocimum sanctum. (Labiateae) leaf extracts were studied in L-thyroxine (0.5 mg/kg) induced hyperthyroidic mice. Separately combined effects of these three plant extracts and of a commonly used antithyroidic drug, Propyl thiouracil (PTU) were investigated for comparison. Serum concentration of thyroxine $(T_4)$, triiodothyronine $(T_3)$, glucose and the activity of hepatic Glucose 6-Phosphatase (G-6-Pase) were considered as main parameters. Hepatic lipid peroxidation (LPO), superoxide dismutase (SOD) and Catalase (CAT) activities were also studied to reveal the toxic effect of the plant extracts, if any. While exogenous $T_4$ enhanced serum concentration of $T_4$, $T_3$, glucose and the activity of hepatic G-6-Pase, a simultaneous administration of either A. marmelos leaf (1.0 mg/kg), E. officinalis fruit( 30 mg/kg) and O. sanctum leaf (50 mg/kg) extracts, to hyperthyroidic animals decreased all these parameters. However, the effects were more pronounced, as nearly normal thyroid function and serum glucose concentration were exhibited when all three plant extracts were administered together. A decrease in LPO and a concomitant increase in SOD and the CAT activities indicated the safe and antiperoxidative nature of the plant extracts, administered either alone or in combination. Our findings reveal that the three test plant materials exhibit synergistic effects without any hepatotoxicity, suggesting their potential use in the amelioration of hyperthyroidism and/ or hyperglycaemia.

Synthesis of Regioselectively Diiodinated Porphyrins; 5,20-Diaryl-12,13-diiodoporphyrins

Panda, Pradeepta K.,Padhy, Sasmita,Ha, Kwon-Soo,Lee, Chang-Hee Korean Chemical Society 2004 Bulletin of the Korean Chemical Society Vol.25 No.9

Validation of primary formaldehyde gas standards prepared by dynamic thermogravimetry through a tri-national comparison of gaseous formaldehyde amount fraction

Panda, N.,Kim, M.,Aoki, N.,Zhou, Z.,Shimosaka, T.,Kim, Y.,Lee, S.,Kim, D. Springer Science + Business Media 2016 Accreditation and quality assurance Vol.21 No.4

<P>A validation study for primary formaldehyde gas standards was performed at three National Metrology Institutes: the Korea Research Institute of Standards and Science (KRISS), the National Metrology Institute of Japan (NMIJ) and the National Institute of Metrology of China (NIM). The studied materials had a nominal amount fraction of 2 mu mol/mol formaldehyde in nitrogen balance and were prepared in 10-L aluminum cylinders by KRISS. The impurities in the materials were analyzed using a gas chromatograph/atomic emission detector and a Fourier-transform infrared spectrometer (FTIR). The stability of the materials was assessed for 1 year by KRISS using paraformaldehyde as a source for the primary standard gas and a cavity ring-down spectrometer (CRDS) instrument as the measurement method. The amount fraction of formaldehyde in the materials decreased linearly by 0.74 % each month. The studied materials that exhibited similar linear rates of decline were distributed to the participants. After the measurement was completed by the participants, the materials were returned to KRISS and the stability analysis based on the primary standard maintained at KRISS was repeated. NMIJ analyzed the materials using paraformaldehyde as the source of the primary standard of formaldehyde and FTIR analysis, whereas NIM used trioxane as the primary standard gas source and CRDS analysis. The results of the comparison revealed good agreement between the results and were within the expanded uncertainty of 2 % although each of them used different combinations of methods in the generation of primary gas standards and measurements.</P>

Solubilization by $\beta$-Cyclodextrin: A Fluorescence Quenching Study

Panda, M.,Mishra, A.K. Korean Society of Photoscience 2002 Journal of Photosciences Vol.9 No.3

Solubility of carbon tetrachloride ($CCl_4$) in water increases appreciably in presence of $\beta$-cyclodextrin ($\beta$CD). $CCl_4$ is a very good quencher of 1-naphthol (1ROH) fluorescence. By studying the quenching of fluorescence of 1ROH included in $\beta$CD cavity, it was found that there is an increase in the availability of $CCl_4$ around $\beta$CD in the aqueous medium. This could help to rationalize the enhanced solubility of $CCl_4$.

Water Quality Assessment for Wells Located Near Municipal Waste Dumping Sites in Bhubaneswar City, India

Panda, S.P.,Mishra, C.S.K.,Muduli, R.,Behera, D.K.,Kim, Jung Wk 서울대학교 환경대학원 2004 環境論叢 Vol.42 No.-

Certain physicochemical and biological characteristics of well waters located near major solid waste disposal sites of Bhubaneswar city were studied in the dry and wet seasons of 2001 and 2002. Higher levels of NO₃^(-), PO₄^(--), Cl^(-), SO₄^(---), Fe, Ca, Mg, total hardness, and total and fecal coliform bacteria have been observed in the water samples in wet seasons relative to dry seasons. Most of the physicochemical and biological parameters exceeded the Indian drinking water standards prescribed by IS:10500:1991. The results indicated that in wet seasons, the well waters within 50 meters from municipal waste dumping sites were not suitable for drinking.

Dynamic friction behavior of ultrananocrystalline diamond films: A depth-resolved chemical phase analysis

Panda, Kalpataru,Rani, Revati,Kumar, Niranjan,Sankaran, Kamatchi Jothiramalingam,Park, Jeong Young,Ganesan, K.,Lin, I-Nan Elsevier 2019 Ceramics international Vol.45 No.17

<P><B>Abstract</B></P> <P>Investigation of dynamic changes in friction behavior of ultrananocrystalline diamond (UNCD) films is a complex mainly because of the rapid change in chemical composition at the sliding interfaces. To address this issue, for the first time, we report chemical phase analysis of transferfilm using the depth-resolved X-ray photoelectron spectroscopy (XPS) technique. The friction coefficient of the UNCD films was high during the initial run-in regime, but it gradually decreased to an ultralow value after longer sliding cycles at the ambient atmospheric tribo-condition. Depth-resolved XPS analysis showed a higher sp<SUP>3</SUP>/sp<SUP>2</SUP> carbon ratio during the initial run-in regime. This ratio decreased with increasing sliding cycles and consequently the friction coefficient decreased. However, a higher value of the friction coefficient throughout the run-in regime persisted at the high-vacuum tribo-condition. In this case, the sp<SUP>3</SUP>/sp<SUP>2</SUP> carbon ratio inside the transferfilm was quite high and no considerable changes were observed in the depth-resolved XPS analysis. This investigation confirmed that the dynamic friction behavior in UNCD films was manipulated by the sp<SUP>3</SUP>/sp<SUP>2</SUP> carbon ratio inside the transferfilm which showed tribo-atmospheric dependence.</P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>