Unplanned 30-Day Hospital Readmissions of Symptomatic Carotid and Vertebral Artery Dissection

Tapan Mehta,Smit Patel,Shailesh Male,Romil Parikh,Kathan Mehta,Kamakshi Lakshminarayan,Ramachandra Tummala,Mustapha Ezzeddine 대한뇌졸중학회 2018 Journal of stroke Vol.20 No.3

THEORY OF KARMA AND ITS KINDS-JAINISM

MEHTA, MUKUL RAJ 서울대학교 종교문제연구소 1998 종교와 문화 Vol.0 No.4

Isolated oculomotor nerve palsy secondary to non-aneurysmal subarachnoid hemorrhage

Mehta Shyle,Bathini Abhijith,Dubey Anwesha,Barpujari Awinita,Kassem Ahmad,Sulaiman Mohanad,Binning Mandy 대한뇌혈관외과학회 2022 Journal of Cerebrovascular and Endovascular Neuros Vol.24 No.3

We present a case series of two patients who developed unilateral cranial nerve III (CNIII) palsy following non-aneurysmal SAH (NASAH). Subarachnoid hemorrhage (SAH) can present with various signs and symptoms. Early diagnosis is paramount to determine treatment course. Thus, clinicians must be aware of the variable clinical presentations of this condition. Two patients were admitted to a single institution for SAH. Patient 1, 52-year-old male, presented with headache, left eye ptosis, and painless diplopia. A non-contrast head computed tomography (CT) demonstrated a SAH within the left sylvian fissure and blood surrounding the mesencephalon and falx. Patient 2, 70-year-old male, presented with mild headache, acute onset of blurry vision, and right eye ptosis. A non-contrast head CT demonstrated a diffuse SAH predominantly in the Sylvian and suprasellar cisterns. Patients were admitted to the neuro intensive care unit and underwent diagnostic angiograms to identify possible aneurysms. Magnetic resonance imaging and angiograms for both patients were negative. Patients were managed with best medical therapy and followed up in the outpatient setting. Unilateral CNIII palsy in the setting of NASAH was identified in both patients. Diagnostic angiograms were negative for aneurysms; therefore, SAH were determined to be spontaneous. We propose that unilateral CNIII palsy is a possible sign of NASAH.

Progress in the biosensing techniques for trace-level heavy metals

Mehta, J.,Bhardwaj, S.K.,Bhardwaj, N.,Paul, A.K.,Kumar, P.,Kim, K.H.,Deep, A. Pergamon Press ; Elsevier Science Ltd 2016 BIOTECHNOLOGY ADVANCES Vol.34 No.1

<P>Diverse classes of sensors have been developed over the past few decades for on-site detections of heavy metals. Most of these sensor systems have exploited optical, electrochemical, piezoelectric, ion-selective (electrode), and electrochemical measurement techniques. As such, numerous efforts have been made to explore the role of biosensors in the detection of heavy metals based on well-known interactions between heavy metals and biomolecules (e.g. proteins, peptides, enzymes, antibodies, whole cells, and nucleic acids). In this review, we cover the recent progress made on different types of biosensors for the detection of heavy metals. Our major focus was examining the use of biomolecules for constructing these biosensors. The discussion is extended further to cover the biosensors' performance along with challenges and opportunities for practical utilization. (C) 2015 Elsevier Inc. All rights reserved.</P>

Analysis of payload compartment venting of satellite launch vehicle

Mehta, R.C. Techno-Press 2017 Advances in aircraft and spacecraft science Vol.4 No.4

The problem of flow through the vent is formulated as an unsteady, nonlinear, ordinary differential equation and solved using Runge-Kutta method to obtain pressure inside payload faring. An inverse problem for prediction of the discharge coefficient is presented employing measured internal pressure of the payload fairing during the ascent phase of a satellite launch vehicle. A controlled random search method is used to estimate the discharge coefficient from the measured transient pressure history during the ascent period of the launch vehicle. The algorithm predicts the discharge coefficient stepwise with function of Mach number. The estimated values of the discharge coefficients are in good agreement with differential pressure measured during the flight of typical satellite launch vehicle.

Prediction of Shear Strength of Exterior RC Beam-Column Joints using Machine Learning Techniques

Mehta Vikas,Jang Sung Hyun,Chey Min Ho 대한토목학회 2023 대한토목학회 학술대회 Vol.2023 No.10

Ratiometric detection of Cu⁺ in aqueous buffered solutions and in live cells using fluorescent peptidyl probe to mimic the binding site of the metalloprotein for Cu⁺

Mehta, Pramod Kumar,Oh, Eun-Taex,Park, Heon Joo,Lee, Keun-Hyeung Elsevier 2018 Sensors and actuators. B Chemical Vol.256 No.-

<P><B>Abstract</B></P> <P>Ratiometric detection of Cu<SUP>+</SUP> in aqueous buffered solutions and live cells is highly recomended. We synthesized a fluorescent probe (<B>1)</B> based on the peptide receptor to mimic the binding site of the metalloprotein (CusF) for Cu<SUP>+</SUP>. <B>1</B> sensitively and selectively detected Cu<SUP>+</SUP> among various biological relevant metal ions in aqueous solutions at physiological pH through a ratiometric response. Job’s plot analysis indicated that <B>1</B> formed a 2:1 complex with Cu<SUP>+</SUP> and the binding affinity of <B>1</B> for Cu<SUP>+</SUP> was measured to be 5.73×10<SUP>−21</SUP> M<SUP>2</SUP> from a competition experiment with bathocuproine disulfonate. The probe showed significant ratiometric responses to Cu<SUP>+</SUP> over a wide range of pH (6.5∼10.5). The binding mode study showed that the imidazole and indole groups of the peptide receptor played a critical role in the tight binding to Cu<SUP>+</SUP>. <B>1</B> penetrated successfully in living A549 cells and detected intracellular Cu<SUP>+</SUP> ions in Golgi apparatus through ratiometric response. Giving the recent growing interests in fluorescent imaging of Cu<SUP>+</SUP>, the development of a fluorescent ratiometric probe (<B>1)</B> based on the peptide receptor to mimic the binding site of the metalloprotein for Cu<SUP>+</SUP> will provide a potential tool for detection of intracellular metal ions in live cells.</P> <P><B>Highlights</B></P> <P> <UL> <LI> The fluorescent peptidyl probe for Cu(I) was easily synthesized in high yield (75%). </LI> <LI> Highly sensitive and selective response to Cu(I) among various biological relevant metal ions. </LI> <LI> Ratiometric response to Cu(I) and the intensity ratio (I<SUB>472</SUB>/I<SUB>396</SUB>) at 472 and 396nm increased by about 130 fold. </LI> <LI> Cell penetration and ratiometric detection of intracellular Cu(I) in the Golgi apparatus in live cells. </LI> </UL> </P>

Graphene quantum dot modified screen printed immunosensor for the determination of parathion

Mehta, J.,Bhardwaj, N.,Bhardwaj, S.K.,Tuteja, S.K.,Vinayak, P.,Paul, A.K.,Kim, K.H.,Deep, A. Academic Press 2017 Analytical biochemistry Vol.523 No.-

<P>The widespread use of pesticides has immense effect on increased crop productions. However, they are also responsible for posing detrimental health hazards and/or for contaminating the environment with chemical residues. A routine and an on-field detection of pesticide residues in different food, water, and soil samples has become a need of the hour for which biosensors can offer a viable alternative. The present work reports a functionalized graphene quantum dot (GQD) based screen printed electro-chemical immunosensor for the detection of parathion. The application of GQDs has permitted the realization of a sensitive, robust, and reproducible sensor unlike those carried out earlier for the similar purposes. This immunosensor exhibited a dynamic linear response for parathion within the range of 0.01 -10(6) ng/L with a very low detection limit of 46 pg/L. According to the analysis of potential interferences, the proposed sensor was specifically detecting parathion even in the presence of its metabolite, paraoxon. The investigations of the proposed sensing approach with respect to stability, response reproducibility, and regeneration have fully supported its potential practical applicability. (C) 2017 Elsevier Inc. All rights reserved.</P>

The Effect of Technology and Open Innovation on Women-Owned Small and Medium Enterprises in Pakistan

MEHTA, Ahmed Muneeb,ALI, Asad,SALEEM, Hina,QAMRUZZAMAN, Md.,KHALID, Rimsha Korea Distribution Science Association 2021 The Journal of Asian Finance, Economics and Busine Vol.8 No.3

Technological adaption and innovative activities foster small and medium enterprises (SMEs) growth, especially women-owned SMEs in Pakistan, However, the impact of technological adaption and innovative activities on SMEs growth in the context of Pakistan has been examined by very researchers. This study aims to identify the effect of technology and open innovation policies on the growth of women-owned SMEs and the present trends and management challenges for successful full implementation of open innovation. The study considered a sample of 693 women enterprises located in different cities in Pakistan. Open innovation is measured through eight innovative practices, reflecting the exploration and exploitation of technology in SMEs. Study findings revealed that women enterprises were involved in several open innovation policies during the last five years. Moreover, the study indicated no significant differences between manufacturing and service SMEs regarding open innovation practices; however, women enterprises are more impressively engaged in open innovation practices. Findings also reveal that women-owned SMEs follow open innovation, mainly for market-related intentions, to compete with competitors and meet customers' demands. Thus, it is suggested that government policy relating to thriving SMEs owned by women should be innovation-oriented. The study contributes to the theoretical and practical implications. Further, the study is helpful for SMEs, researchers, practitioners, and decision-makers.

Synthesis and Characterization of Some Quinazoline Derivatives as Potential Antimicrobial Agents under Microwave Irradiation

Mehta, Sarika,Swarnkar, Neelam,Vyas, Madhuri,Vardia, Jitendra,Punjabi, Pinki B.,Ameta, Suresh C. Korean Chemical Society 2007 Bulletin of the Korean Chemical Society Vol.28 No.12

Under the framework of green chemistry, an efficient and extremely fast procedure for the synthesis of 5a-h through four-step procedure starting from 2-arylidenetetralin-1-one 1a-d under microwave irradiation is described. A considerable increase in the reaction rate has been observed with better yield. The structures of the synthesized compounds have been characterized on the basis of their elemental analysis and spectral data. Synthesized compounds 5a-h was evaluated for their antimicrobial activity. Some of the compounds exhibited appreciable activity.